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The potential for this work to change and save many lives is extraordinary; people with PTSD often suffer such severe anxiety and depression that they withdraw from their lives and even commit suicide. Unfortunately, the research is expensive. If you would like to help, consider making a donation. The safest way to take MDMA and most other drugs is orally, by swallowing the drug. The digestive system is fairly tough, having evolved to handle all sorts of nasty things like poisons, spoiled food, bacteria, etc. Certainly it dissolves easily , although alkaloids MDMA and many other drugs are often very bitter-tasting. Having a bottle of water or juice or who knows what spiked with MDMA does create a danger of accidental poisoning. So if you do want to drink your molly, be careful not to leave the spiked beverage sitting around where others might find it! Yes, MDMA is generally illegal to make , have, or sell. As a result, MDMA is more or less illegal in most possibly all countries. For example, a gram of MDMA contains perhaps eight doses. But a gram of LSD contains around 10, doses! So, it does have a smell. How much LSD would you need to have on you in order for it to smell strongly enough for a dog to detect? Instead, they are trained to identify specific drugs. Some dogs are trained to sit down next to the item and wait. As a result, most dogs will only alert on a couple of different drugs. The drug sniffing dog is one of the most notoriously abused police tactics: For more information on what your rights are, check out Flex Your Rights. MDMA can reduce blood flow to your skin, which makes it harder to lose heat to your surroundings. It can also greatly increase metabolism, causing your body to produce a lot more heat. Angry parents and medical bills are never as big a problem as being dead. So, yes; real MDMA can kill you. The safest thing to do is not use drugs, but the next best thing is to use in moderation. Which is to say, the wiring tends to work pretty much the same in dogs, rats, humans, etc. The first problem is dosage. A wrong assumption could result in a fatal overdose for your dog. MDMA overdoses can be a spectacular death ; your body temperature runs out of control, you start to bleed internally, and your organs break down one after another. Assuming you could figure out what the right dosage is, your dog might not handle getting high very well. If not, they may be severely traumatized or even killed. Have a question, crazy or otherwise? Feel free to contact me. Or, swing by the Bluelight forums and join the discussion! This has led some people to speculate that MDMA made with this new method might have a different balance of isomers. Isomers are slightly different forms of the MDMA molecule, much the way a right and left shoe are almost identical, but mirror images of each other. The other isomer, R - , is mostly a serotonin releaser and could be thought of as the warmth and empathy of the MDMA high. PMK glycidate the starting material for the currently most popular method has a bias; each molecule starts out as one isomer or another. As a result, the end product is still randomly formed, giving a Which seems like it would solve the debate, but there is one potential catch: The new method might in some cases introduce new contaminants that could, in theory, affect the high. You can e-mail me , or join the discussion at Bluelight. Tandy hailed this record level of seizures as proof that the drug war was working. Roaring success is all a matter of perspective, it seems. I found the answer. Long-term use of meth can take a heavy toll on a person, of course, but few examples of meth wear-and-tear are as graphic as the sort of severe tooth deterioration seen here. Bacteria like to live on our teeth, since they get fed whenever we eat. In order to make sure they can literally stick around in the mouth the bacteria turn sugar into the sticky stuff we know as plaque. The metabolism of the bacteria creates a lot of acid as a waste product. The outer layer of a tooth the white part we see is enamel. The enamel is mostly a crystal of calcium phosphate, which acid can slowly eat away. Chewing gum increases saliva production. Our main behavioral defense is brushing our teeth, since brushing can remove most of the bacteria and plaque that have built up during the day. Heavy meth use is a sort of perfect storm for tooth destruction. It reduces saliva production part of a water-conserving stress response that also contributes to hyponatremia deaths among ecstasy users , making it easier for acid levels to build up. Heavy meth users tend not to visit a dentist, either for regular checkups or even when there clearly is deterioration. The acid acts like tiny magnets, holding the meth molecules together into crystals. If you removed the acid, you would have methamphetamine freebase, which is an oily liquid; a bit hard to transport and sell. Stimulants like meth and ecstasy, for that matter also tend to cause bruxism clenching and grinding your teeth. Nobody gets addicted from one dose. The only entirely safe drug use is not to use. If you do use, safer drug use means limiting dosages and the frequency of use. If your usage or side effects creep upwards over time, take a break for several months. Perhaps taking a new interest in what may become a commercially valuable drug, Merck, the company that first created MDMA in , has gone through their own records to find out what exactly they did create the substance for. Nobody knew MDMA was a psychoactive drug at first. Animal experiments were performed, but the details have been lost beyond some notes that MDMA was somewhat toxic and promoted muscle contraction, etc. In MDMA appeared again at Merck in the form of a brief note that flies exposed to the substance became unconscious, then died. The first human tests may have occurred in or shortly thereafter. Given that emotionally troubled people are also at greater risk of drug addiction, childhood mental health intervention may prove to be an invaluable tool for combating drug abuse and addiction later in life. The use of ayahuasca for shamanic practices and healing rituals dates back thousands of years in South America. There are about members in the US although the church has a far larger presence in Brazil. The group came under fire when customs intercepted a shipment of the sacramental tea apparently 14 previous shipments of the drug-laced liquid had gone unnoticed. Faced with the loss of their central religious sacrament and threats of arrest, the Church sued the US government, claiming that the Religious Freedom Restoration Act a law passed in primarily to protect the rights of peyote using Native American tribes exempted them from the Controlled Substances Act which outlaws DMT. The government countered that there was a compelling interest as required by the RFR Act to stop the use of ayahuasca to 1. Protect the health of Church members; 2. Prevent diversion of the tea to the black market; and 3. To uphold international UN drug control treaties. The court ruled that the government had failed to make a convincing argument on any of these grounds, upholding the decision of a lower court that the Church had the right to practice their religion by using ayahuasca. While certainly a triumph for the UDV, this ruling may also pave the way for other religious groups who use psychoactive drugs as part of their practices such as the Rastafarians , who use marijuana, albeit in a less ritualized manner than the UDV uses ayahuasca. Read the Supreme Court Ruling. Lurid tales of drinks spiked with incapacitating drugs have long been a press favorite, whipping up public hysteria over drugs like GHB and Rohypnol, in spite of such cases paling in numbers compared to alcohol-facilitated rapes. British researchers, however, have recently thrown some doubt on the scale of the problem in the form of a study of the toxicology results from over a thousand people who believed that they had been drugged in order to make them vulnerable to sexual assault. These are people so sure that they had been drugged that they went to the police and were drug tested. Still, the research paints a very surprising picture: Pre-publication copy of article without data tables. Can drug dogs smell acid LSD? Can you die from real MDMA? Is molly different these days because of a new way of making it? Can it really make holes in your brain? The history of MDMA. Read the journal article.

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