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The specificity and mechanism of the Scott reaction for cocaine screening were studied. Our experiment using 30 drugs showed that the precipitate-forming reaction of the first step above was not specific for cocaine. Promazine, promethazine, chlorpromazine, imipramine, lidocaine and diltiazem showed positive reaction when 5 mg or more of these drugs were used. These findings indicated that the specificity of the Scott reaction is markedly affected by the amount of a drug used. The stoichiometric study indicated that cocaine binds to cobaltous thiocyanate at a molar ratio of 2 : 1. Based on this finding together with the specificity of the Scott reaction, we postulated a structure of cocaine-cobaltous thiocyanate. Chemical and Pharmaceutical Bulletin. Biological and Pharmaceutical Bulletin. Journal of Health Science. Already have an account? Sign in here. Eisei kagaku. Journal home All issues About the journal. Corresponding author. Keywords: cocaine , cobaltous thiocyanate , complex formation , cross reactivity , stoichiometry. Article overview. References 5. Related articles 0. Figures 0. Content from these authors. Supplementary material 0. Result List. Previous article Next article. Related articles. Share this page. Register Already have an account?

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Kitakyushu buy cocaine

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Kitakyushu buy cocaine