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Kiel Kaufen Sie Methamphetamin
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Kiel Kaufen Sie Methamphetamin
Méthamphétamine
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240 закладок наркотиков обнаружили на кладбищах Уфы
He became the first Briton ever to win a medal in alpine skiing. After that, things rapidly went downhill for Baxter. Within days, tests on a urine sample revealed traces of methamphetamine. After a 2-day hearing, the International Olympic Commission announced on March 21st that Baxter must return his bronze medal. His 3rd place would be removed from the Olympic record books. Alain Baxter had a longstanding medical condition, nasal congestion. Back in the UK, he regularly used British Vicks nasal inhalers. These use chemicals such as menthol, camphor and methyl salicylate wintergreen and exert their effect through shrinking inflamed membranes. Sadly although it looks the same, American Vicks contains compounds not found in the British version, including L-methamphetamine. L-methamphetamine is simply a decongestant, and has no stimulant activity. But its optical isomer, D-methamphetamine , is the stimulant commonly known as speed. Methamphetamine is the methyl-derivative of the amphetamine molecule, which also has optical isomers. The D- form is often called Dexedrine , and is another stimulant often used to treat insomnia, ADHD, narcolepsy, fatigue and sometimes depression. The methyl group that replaces the H in amphetamine to make methamphetamine is shown in blue in the structures above and below. IOC regulations simply forbid the use of 'methamphetamine'. They do not distinguish between the two isomers. The optical isomers of methamphetamine can be separated and distinguished by high pressure liquid chromatography HPLC using a chiral column. Baxter requested that the IOC tested his urine samples to confirm which isomer was present, a request that was declined. Methamphetamine contains a chiral carbon atom, and therefore exists as two optical isomers, non-superimposable mirror images of each other. The isomers have identical chemical reactions, solubilities and melting points. They just differ in their opposite rotations of plane-polarised light and, because they have different 3-D structures, they fit chiral protein receptors differently, and therefore have different effects upon the body. Laboratories in many places, notably throughout the USA, are engaged in clandestine manufacture of methamphetamine. The chemistry is well understood, and widely published, notably on the web, though not easy to achieve. It is the synthesis of methamphetamine that is illegal. Two methods that have been described both involve the reduction of ephedrine itself readily available using either lithium in liquid ammonia as the reducing agent, or else red phosphorous and iodine to generate HI for the reduction. A further process involves the reductive amination of phenylacetone, first converting it into the formyl amide of methamphetamine, then hydrolysing the amide with HCl aq. Much of this synthetic chemistry is difficult and dangerous outside a proper laboratory, fires and explosions, as well as chemical burns to individuals, are reportedly common. It promotes release of abnormal amounts of the important neurotransmitter dopamine. This has the effect of stimulating regions of the brain linked with vigilance and the action of the heart. For a short while, the user feels sharper, stronger and more energetic. It is believed that a significant proportion of the dopamine-producing cells in the brain can be damaged by prolonged exposure to even low levels of methamphetamine, and this is responsible for reduced levels of dopamine; this can affect memory-, attention- and decision-taking functions. Chronic methamphetamine abuse is reported to lead to significant reduction in grey matter in the brain, greater than those in dementia or schizophrenia patients, though this needs further clarification. Associated health risks involve social and family problems, including risky sexual behaviour. Drug-induced psychosis may result. Because the free amphetamine and methamphetamine molecules are rather insoluble oily liquids, they are usually handled as salts, such as methamphetamine hydrochloride. This dissociates in the body, liberating the free amine. Amphetamine itself was first made in , and methamphetamine in Under the nomenclature system of the time, amphetamine was originally called a lpha- m ethyl ph enyl et hyl amine , which was shortened to 'amphetamine'. It was not until that it was discovered that amphetamine raised blood pressure; in , after it was found to shrink mucous membranes, Smith, Kline and French marketed a nasal inhaler containing amphetamine as Benzedrine to treat nasal congestion. Within a short period of time, people found that it could be extracted from the wadding in inhalers and used for its 'high', so it became a prescription medicine. Amphetamine abuse had begun. Printed accounts often use 'amphetamine' as a generic title, without distinguishing between methamphetamine and amphetamine itself The presence of the methyl group on the side chain in both amphetamine and methamphetamine means that they are resistant to the monoamine oxidase enzyme which decomposes the kinds of amines that we ingest in foods like cheese, including phenylethylamine, also found in the brain. The first really large-scale amphetamine abuse occurred in Japan immediately after World War II, when stocks formerly used by the military and supplied by Germany flooded the market, and it took a strict campaign to bring things under control. After , they became prescription drugs in the USA and were widely prescribed as pick-me-ups. They were once used as a slimming aid, as they reduced appetite. Amphetamine tablets became known as 'pep pills. Under the influence of amphetamines, Jack Kerouac produced 'On the Road' in one continued frenzy of typing in three weeks of April though many of its ideas had already been published. Indeed, amphetamines were used widely by American, British, German and Japanese forces. Adolf Hitler had daily injections of methamphetamine from his personal physician during the last three years of the war. Bomber crews used amphetamines to maintain alertness on long night missions; watch-keepers on ships used them to stay alert too. But they are still in use as pep pills. On April 17th , USAF bomber pilots on amphetamine 'go pills' mistakenly bombed Canadian forces in Afghanistan, killing four and wounding eight. The USAAF says that the amphetamine was issued to keep them awake on long missions just like 60 years ago. They are Schedule II drugs. Illegal production in the USA has been associated with biker gangs as it has spread from San Francisco into the Midwest. Amphetamines powered much of s British youth culture, particularly the Mods. Here comes the nice, looking so good, He makes me feel like no-one else could. Among the many celebrated victims of methamphetamine abuse, Johnny Cash , the American singer, survived. He found God. Others were not so lucky. Methamphetamine started to be known as 'speed' in the early s, possibly a consequence of its use in 'speedballs' with heroin, possibly because of its go-faster characteristics. In the Haight-Ashbury region of San Francisco, the 'Summer of Love' in turned sour the following year when many residents had moved on from marijuana and psychedelics like LSD to injecting methamphetamine intravenously. The resulting epidemic of methamphetamine abuse and consequent illnesses and crime led to the neighbourhood changing to a less friendly, indeed dangerous, one, and its motto changed from 'peace and love' to 'speed kills'. For many years, methamphetamine was 'available' in tablet form or as a powder. In the late s, 'crystal meth' or 'ice' became available in Hawaii, produced in Far Eastern laboratories by careful recrystallisation of methamphetamine hydrochloride, resulting in quite large, clear, crystals see photo below. Though a salt, it is volatile enough to vapourise unchanged unlike amphetamine sulphate. Its use spread to the American mainland. Methamphetamine abuse has become a real problem right across the country, becoming the leading illicit drug in rural USA. At the Oslo Winter Olympics reportedly several speed skaters who had been taking amphetamines needed medical assistance. As others have remarked, this gave a whole new meaning to the expression 'speed skating'. However, at the Olympics held in Rome, the Danish cyclist Kurt Jensen collapsed and died of a heart attack from an amphetamine overdose, whilst on 13th July Tom Simpson photo right , World Champion and the first Briton to wear the famous yellow jersey, collapsed from heat exhaustion on Mont Ventoux during the Tour De France. A short distance later he collapsed and was taken to hospital by helicopter. Three hours later he was dead from heart failure. They found amphetamines in his jersey. Amphetamines allowed him to go beyond his pain threshold, but they also caused blood to flow away from the skin and thus increased the risk of heat stroke. Back to Molecule of the Month page.
Kiel Kaufen Sie Methamphetamin
Methamphetamine
Kiel Kaufen Sie Methamphetamin
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Kiel Kaufen Sie Methamphetamin