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Carfentanil or carfentanyl is an analog of the synthetic opioid analgesic fentanyl. The toxicity of carfentanil in humans and its ready commercial availability has aroused concerns over its potential use as a weapon of mass destruction by rogue nations and terrorist groups. Carfentanil was first synthesized in by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. The effects of carfentanil, including overdose, can be reversed by naloxone. In , a team of researchers at the British chemical and biological defence laboratories at Porton Down found carfentanil and remifentanil in clothing from two British survivors of the Moscow theater hostage crisis and in the urine from a third survivor. The team concluded that the Russian military used an aerosol mist of carfentanil and remifentanil to subdue Chechen hostage takers. Authors of a previous paper in the Annals of Emergency Medicine surmised from the available evidence that the Moscow emergency services had not been informed of the use of the agent, but were instructed to bring opioid antagonists. Not knowing to expect hundreds of patients exposed to high doses of strong opioids, the emergency workers did not bring enough naloxone or naltrexone the two most commonly-used opioid antagonists to counteract the carfentanil and remifentanil and save the lives of many of the victims. According to an Associated Press article from , 'Chemical weapon for sale: Authorities in Latvia and Lithuania reported seizing carfentanil as an illicit drug in the early s. In June the Royal Canadian Mounted Police seized one kilogram of carfentanil shipped from China in a box labeled 'printer accessories'. According to the Canada Border Services Agency, the shipment contained 50 million lethal doses of the drug, more than enough to wipe out the entire population of the country, in containers labeled as toner cartridges for Hewlett-Packard LaserJet printers. What to Know About Carfentanil', reports over cases of overdose related to fentanyl and fentanyl analogues and several deaths connected to the drug since August in several of the United States, including Ohio , West Virginia , Indiana , Kentucky and Florida. Carfentanil is added to or sold as heroin because it is less expensive, easier to obtain until China added it to its list of controlled substances on 1 March , it was legal for Chinese firms to advertise and sell carfentanil over the Internet, offering advice to customers in other countries on how to import it illegally and easier to make than heroin. The article quoted Andrew C. We are also concerned that groups like ISIS could order it commercially. Carfentanil has been controlled in China since 1 March Carfentanil is specifically controlled as a Class A drug since \\\\\\\\\\\\\\\\\[20\\\\\\\\\\\\\\\\\]. From Wikipedia, the free encyclopedia. Not to be confused with Carfenil. Anlage I Authorized scientific use only UK: Moscow theater hostage crisis. Retrieved December 14, Retrieved 12 April The Journal of Zoo Animal Medicine. Journal of Analytical Toxicology. A medical toxicology perspective'. Annals of Emergency Medicine. Are we missing the signs? Highly potent and on the rise in Europe'. International Journal of Drug Policy. Retrieved 17 April Tip of the Iceberg? Office of Public Sector Information. Retrieved 15 June Analgesics N02A , N02B. Meclofenamic acid Mefenamic acid. Cannabidiol Cannabis Nabilone Nabiximols Tetrahydrocannabinol dronabinol. Gabapentin Gabapentin enacarbil Pregabalin Ziconotide. Carbamazepine Lacosamide Local anesthetics e. Agonists abridged; see here for a full list: Retrieved from ' https: Views Read Edit View history. This page was last edited on 15 September , at By using this site, you agree to the Terms of Use and Privacy Policy. Calcium blockers Gabapentin Gabapentin enacarbil Pregabalin Ziconotide.

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