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Heroin, methamphetamine and ketamine have been the most commonly abused drugs in Taiwan. The presence of these drugs and their metabolites in postmortem specimens has been routinely monitored in our laboratory mostly by gas chromatographic-mass spectrometric methods. This study aimed to evaluate a more effective approach to simultaneously quantify these analytes i. Samples 1 mL were extracted via solid-phase extraction, evaporated and reconstituted in the mobile phase for injection into the LC—MS-MS system. Respective deuterated analogs of these analytes were used as internal standards. Mass spectrometric analysis was performed by electrospray ionization in positive-ion dynamic multiple reaction monitoring mode with optimized collision energy for respective precursor ion selected for each analyte, and the monitoring of two transition ions. Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. 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Ray H Liu. South Birmingham, AL You-Zung Hsieh. Shu-Pao Wu. E-mail: spwu mail. Revision received:. Select Format Select format. Permissions Icon Permissions. Abstract Heroin, methamphetamine and ketamine have been the most commonly abused drugs in Taiwan. Issue Section:. You do not currently have access to this article. Download all slides. Sign in Get help with access. Society of Forensic Toxicologists members Sign in through society site. Institutional access Sign in through your institution Sign in through your institution. Get help with access Institutional access Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. If you are a member of an institution with an active account, you may be able to access content in one of the following ways: IP based access Typically, access is provided across an institutional network to a range of IP addresses. 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