Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review.2019

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review.2019


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Функции для здоровья и связанные с ними молекулярные механизмы компонентов чая: обновленный обзор, 2019 г.

Сгенерированная сводка:

Заключение В заключение, полифенолы, полисахариды, сапонины, пигменты, пуриновые алкалоиды и свободные аминокислоты в чае могут быть основными биологически активными компонентами, которые способствуют его разнообразным оздоровительным функциям.
Как правило, биодоступность фитохимических веществ чая относительно низкая, и некоторые технологии, такие как технология модификации, технология капсул и нанотехнология, могут улучшить их биодоступность, что приводит к повышению биоактивности.
Необходимо дополнительно прояснить механизмы, лежащие в основе оздоровительных функций чая, особенно молекулярные мишени.
Синергетические эффекты чая и его очищенных биоактивных компонентов с другими биологически активными ингредиентами пищевых продуктов заслуживают дальнейшего изучения для улучшения его оздоровительных функций.
В целом чай является многообещающим диетическим компонентом, и его потребление показывает множество функций для здоровья.


Abstract:

Conclusion

In conclusion, polyphenols, polysaccharides, saponins, pigments, purine alkaloids, and free amino acids in tea can be the major bioactive components that contribute to its diverse health functions. Generally, the bioavailability of tea phytochemicals is relatively low, and some technologies, like modification technology, capsule technology, and nanotechnology, can improve their bioavailability, resulting in the increased bioactivities. The antioxidant, anti-inflammatory, immuno-regulatory, anticancer, cardiovascular-protective, anti-diabetic, anti-obesity, and hepato-protective effects have been widely demonstrated by in vitro, in vivo, and human studies, with various mechanisms of actions. Tea brewing and tea-based products are generally considered safe to consumers, as harmful impacts on animals and human have seldom been reported. Although heavy metals, pesticide residues, and mycotoxins could be detected in certain samples of tea, they are usually below the MRLs. Therefore, tea consumption can be recommended to the public for chronic disease prevention and treatment. In addition, tea can be processed into beverages, functional foods, and pharmaceuticals. In the future, the bioavailability of tea phytochemicals should be intensively investigated, and more technologies should be developed to improve their bioavailability. Underlying mechanisms of the health functions of tea, especially the molecular targets, need to be further clarified. In addition, more well-designed clinical trials are necessary to further verify its health functions. Besides, the synergetic effects of tea and its purified bioactive components with other food bioactive ingredients are worth further study to promote its health functions. Last but not least, more attention should also be paid to the safety of tea, such as contamination by heavy metals, pesticides, and mycotoxins, as well as the potential adverse impact of high doses of tea bioactive components. Overall, tea is a promising dietary component, and its consumption shows many health functions.

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