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For full functionality, it is necessary to enable JavaScript. Here are instructions how to enable JavaScript in your web browser. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries. Learn more in our Privacy Policy. We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. We may share your information with third-party partners for marketing purposes. To learn more and make choices about data use, visit our Advertising Policy and Privacy Policy. Log in with your Medical News Today account to create or edit your custom homepage, catch-up on your opinions notifications and set your newsletter preferences. Sign up for a free Medical News Today account to customize your medical and health news experiences. It is also called 4-methylmethcathinone 4-MMC , or 4-methylephedrone, and should not be confused with methadone, which is a totally different substance. Mephedrone is considered a recreational drug. This means that people use it occasionally for enjoyment, and there is no medical justification for its psychoactive effects. Mephedrone is a psychoactive drug. Psychoactive drugs produce distinctive emotional and social effects. The effects of mephedrone are similar to those of ecstasy MDMA. It is an amphetamine and a cathinone. However, the study also states that the negative effects are potentially more severe. An amphetamine is a drug that stimulates the central nervous system CNS. If used too much, it can be physically and psychologically addictive. Cathinone is a naturally occurring stimulant found in the Khat plant of East Africa. Its structure and effects are similar to those of ephedrine and amphetamine. Public health officials are concerned about synthetic cathinones and other types of 'new psychoactive substances' NPS , or 'legal highs. An NPS is an unregulated substance that mimics existing drugs. They often have altered chemical structures that help them avoid becoming illegal. They are sometimes called legal highs because the change in chemical means they are no longer illegal. Some countries have adapted their drug laws and made such drugs illegal, regardless of their exact chemical content. It can come in the form of tablets, capsules, or white powder. Users may swallow, snort, or inject mephedrone, but snorting is the most common way of taking the drug. Users of mephedrone say that it gives a feeling of stimulation, and that it boosts the following functions:. People using mephedrone report that the effects of mephedrone last about an hour. They are similar to a combination of ecstasy and cocaine. Mephedrone is a recreational drug without any medical application. Many users believe that its occasional use is not habit-forming, but this has not been proven. Studies suggest that it induces a 'binge-like craving. Methadone is a pharmaceutical medication. It is a synthetic opiate used as a very powerful painkiller to treat people who are addicted to heroin. This medicaton is a legal substitute for heroin in treatment programs, and is given to patients in the form of a green liquid at drug treatment clinics. Research has indicated that prolonged use of mephedrone can lead to paranoia , depression , hallucinations, and severe panic attacks , as well as adverse effects on the heart, arteries, and kidneys. Excessive stimulation of the CNS can lead to headaches , insomnia , and a rapid heartbeat. People who snort the drug may have nosebleeds and damage to the tissues and structures inside the nose. The drug can cause grinding of the teeth, nausea, vomiting, and a suppressed appetite. It has also been linked to impotence. A number of deaths have been linked to use of the drug. Growing numbers of people are injecting the drug. This involves a risk of infection, for example with hepatitis C or HIV , or damage to veins, leading to an abscess, a blood clot, or gangrene. Unlike many other recreational drugs, such as amphetamines and ecstasy, mephedrone was not first developed as a medicine but in backstreet laboratories. It has not been tested on humans. As a result, it is not known what the medium-term, long-term, or many of the short-term effects might be. Users may take larger doses to get the same effect, so it cannot be seen as less harmful than ecstasy or amphetamines. More scientific research is needed into the effects of mephedrone. Most countries had already banned or restricted its use by Experts say it is too early to tell whether the drug is addictive or not, because it has not been in use for long enough to fully study the long-term effects of mephedrone use. A significant number of users take another dose after an hour, when the effects start to wear off. As a result, users may consume more than they intended to, and they may find it hard to stop. More evidence is needed to determine whether the drug can cause addiction. The drug appears to have first become available in , according to a European Union knowledge tool called The Psychonaut Research Project. It was at this time the purchase of the drug started to be discussed on forums. The first reported seizure of mephedrone happened in French police sent a tablet they assumed to be ecstasy for analysis. However, the chemical structure turned out to be different. However, mephedrone was synthesised far earlier, in , under a different name — toluyl-alpha-monomethylaminoethylcetone. Similar drugs surfaced in Israel before being made illegal in , around the time it was emerging across Europe. An emergency ban was placed on mephedrone and related substances in the United States in It is a Schedule 1 controlled substance under Federal law and banned in most states. The ban was made permanent in the U. Article last updated by Adam Felman on Fri 23 February All references are available in the References tab. DEA moves to emergency control synthetic stimulants. Addiction, 4 , The preclinical pharmacology of mephedrone; not just MDMA by another name. British Journal of Pharmacology, 9 , Mephedrone 4-methylmethcathinone -related deaths \\\\\\\\\\\\\[Abstract\\\\\\\\\\\\\]. Journals of Analytical Toxicology, 35 3 , Does it cause impotence? Is 4-methylephedrone, an 'Ecstasy' of the 21st century? Annales de Toxicologie Analytique, 21 4 , Psychopharmacology, , Acute behavioral effects, hyperthermic, and pharmacokinetic profile in rats. Frontiers in Psychiatry, 8 , Synthetic cathinones 'Bath salts'. MNT is the registered trade mark of Healthline Media. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Privacy Terms Ad policy Careers. This page was printed from: Get the most out of Medical News Today. Subscribe to our Newsletter to recieve: Professionally-verified articles Daily or weekly updates Content custom-tailored to your needs Create an account. More Sign up for our newsletter Discover in-depth, condition specific articles written by our in-house team. Please accept our privacy terms We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. Sign in Log in with your Medical News Today account to create or edit your custom homepage, catch-up on your opinions notifications and set your newsletter preferences. Register for a free account Sign up for a free Medical News Today account to customize your medical and health news experiences. Register take the tour. Reviewed by Alan Carter, PharmD. Fast facts about mephedrone Mephedrone is a psychoactive, recreational drug that has no medicinal use. It is a stimulant and has similar effects to ecstasy. It may trigger paranoia, headaches , heart palpitations, damage to the nasal passages, and other health problems. Some fatalities have been linked to its use. Mephedrone is a synthetic, psychoactive stimulant. Mephedrone is a recreational drug that carries a number of health risks. This content requires JavaScript to be enabled. Please use one of the following formats to cite this article in your essay, paper or report: If no author information is provided, the source is cited instead. While obesity can raise heart failure risk at any age, the risk is higher in those with a lifetime history of obesity compared with only recent obesity. Type 2 diabetes and cognitive decline: New research examines cognitive function and brain atrophy in both people with and without type 2 diabetes over the course of approximately 5 years. How to prevent festive weight gain without exercising. A new study investigates whether a simple, brief intervention might help people avoid putting on extra pounds over the holiday season. How to make kefir more healthful using sound. Kefir is credited with a range of health benefits. Recently, researchers tried to boost levels of one of its active ingredients using ultrasound. What is the best way to sober up? Can you treat opiate withdrawal symptoms at home? What you should know about date rape drugs. Subscribe Your privacy is important to us.

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