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We use cookies to operate our website. For more information about how we use cookies, please see our Website Terms of Use. Supporting Latinx Health Research. Login to edit your profile add a photo, awards, links to other websites, etc. Education and Training. My research focus is on the development of mass spectrometric techniques and their application to environmental biomonitoring, clinical toxicology, and therapeutic drug monitoring in MDR-TB patients. In biomonitoring, my laboratory is pioneering the application of high resolution mass spectrometry to the suspect screening of environmental chemicals in biological samples. We have have also continuously developed innovative and sensitive liquid chromatography- mass spectrometry LC-MS methods for measuring environmental chemicals e. In I established the Pshychoactive Substances Consortium and Analysis Network PSCAN , a consortium of ten medical centers prospectively collecting cases that may have NPS etiology to pair comprehensive clinical data with NPS analysis data in their corresponding biological samples with the aim of potentially defining toxidromes specific to various NPS classes. The panel is currently being used for drug adherence monitoring among multi-drug resistant TB patients. Gerona Lab Site. In The News. Research Activities and Funding. ORNG Applications. Featured Publications. Collaboration Interests. Researchers can login to make corrections and additions, or contact us for help. Arthritis Rheumatol. PMID: Plasma concentrations of phenibut and mitragynine in a single patient. Clin Toxicol Phila. PLoS One. Abarca R, Gerona R. Clin Pharmacokinet. Glyphosate exposure and preterm birth: A nested case-control pilot study. Reprod Toxicol. J Emerg Med. J Med Toxicol. Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects. ACS Chem Neurosci. Glyphosate exposure in early pregnancy and reduced fetal growth: a prospective observational study of high-risk pregnancies. Environ Health. Open Forum Infect Dis. View in: PubMed Mentions: 2. Front Psychiatry. View in: PubMed Mentions: 1. Drug testing in the era of new psychoactive substances. Adv Clin Chem. Gerona RR , French D. Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism. Nat Microbiol. Obstetric risk in pregnancy interacts with hair cortisone levels to reduce gestational length. Front Glob Womens Health. Microbiol Res. A critical review of drug testing policy in the Philippines. Drug Science Policy and Law. View in: Publisher Site Mentions:. Bisphenol-A analogs induce lower urinary tract dysfunction in male mice. Biochem Pharmacol. Environ Sci Technol. Am J Case Rep. RSC Med Chem. View in: PubMed Mentions: 8. Quantity of phenibut in dietary supplements before and after FDA warnings. Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco. A pilot study of glyphosate, and preterm birth among blacks and whites. Organophosphate and organohalogen flame retardant exposure and thyroid hormone disruption in women firefighters and office workers from San Francisco. Running the Red Queen's race-investigating environmental phenols as potential contributors to preterm birth. Fertil Steril. Elevated levels of perfluoroalkyl substances in breast cancer patients within the Greater Manila Area. A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum. J Antimicrob Chemother. Toxicol Sci. Drug Test Anal. Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites. Sci Rep. J Anal Toxicol. Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting. BMC Infect Dis. Measuring TB drug levels in the hair in adults and children to monitor drug exposure and outcomes. Int J Tuberc Lung Dis. Development and validation of a liquid chromatography-tandem mass spectrometry method for quantifying delamanid and its metabolite in small hair samples. A pilot investigation of couple-level phthalates exposure and in vitro fertilization IVF outcomes. View in: PubMed Mentions:. Sources of exposure to urinary phthalates among couples undergoing infertility treatment. Int J Hyg Environ Health. J Vis Exp. BPA and risk assessment - Authors' reply. Lancet Diabetes Endocrinol. Biopreserv Biobank. Antimicrob Agents Chemother. Chapter Am J Trop Med Hyg. Association of differential symptoms of stress to hair cortisol and cortisone concentrations among pregnant women in Kenya. BPA: have flawed analytical techniques compromised risk assessments? Simultaneous analysis of 29 synthetic cannabinoids and metabolites, amphetamines, and cannabinoids in human whole blood by liquid chromatography-tandem mass spectrometry - A New Zealand perspective of use in Evidence of a potential mechanism for Kratom-related cardiac arrest. Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance. Exposure to perfluoroalkyl substances in a cohort of women firefighters and office workers in San Francisco. Integrating exposure knowledge and serum suspect screening as a new approach to biomonitoring: An application in firefighters and office workers. ERJ Open Res. Organic diet intervention significantly reduces urinary pesticide levels in U. Environ Res. Chemical Contaminants from Plastics in the Animal Environment. Deaths in Colorado Attributed to Kratom. N Engl J Med. Clonazolam: a novel liquid benzodiazepine. Toxicology Communications. An outbreak of synthetic cannabinoid exposures reported to a regional poison center: 'K2' identified as 5F-ADB. A novel synthetic cannabinoid Cumylcyano-BINACA resulting in hyperthermia, rhabdomyolysis, and renal failure in a year-old patient: it's not meningitis. Pediatr Emerg Care. Curr Biol. Environ Health Perspect. Severe illness associated with reported use of synthetic cannabinoids: a public health investigation Mississippi, Stimulant drugs are associated with violent and penetrating trauma. Am J Emerg Med. Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study. The chemistry and pharmacology of synthetic cannabinoid SDB and its regioisomeric fluorinated and methoxylated analogs. View in: PubMed Mentions: 5. A Case of Opioid Overdose? Or Is It?. The Journal of Applied Laboratory Medicine. Or Is It? J Appl Lab Med. French D , Gerona RR. Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis. New Psychoactive Substances in Pediatric Patients. Pediatr Clin North Am. Journal of Drug Metabolism and Toxicology. Suspect screening of maternal serum to identify new environmental chemical biomonitoring targets using liquid chromatography-quadrupole time-of-flight mass spectrometry. J Expo Sci Environ Epidemiol. Clemastine fumarate as a remyelinating therapy for multiple sclerosis ReBUILD : a randomised, controlled, double-blind, crossover trial. J Psychoactive Drugs. Ann Intern Med. Nat Med. Prehosp Emerg Care. Ann Emerg Med. Acad Emerg Med. Fentanyl and other synthetic opioids sold as counterfeits in deadly new trend. The Conversation. View Publication. A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs. Direct measurement of Bisphenol A BPA , BPA glucuronide and BPA sulfate in a diverse and low-income population of pregnant women reveals high exposure, with potential implications for previous exposure estimates: a cross-sectional study. Non-targeted screening for novel psychoactive substances among agitated emergency department patients. Quantitative analysis of powdered caffeine products purchased from the Internet using liquid chromatography-quadrupole time-of-flight mass spectrometry. State of Alaska Epidemiology Bulletin. Labs make new, dangerous synthetic cannabinoid drugs faster than we can ban them. Synthetic Cannabinoid-Related Illnesses and Deaths. Altered mental status and end organ damage associated with the use of gacyclidine: a case series. Internet-purchased ibogaine toxicity confirmed with serum, urine, and product content levels. Pediatr Nephrol. Identification of N-Hydroxy-para-aminobenzoic acid in a cyanotic child after benzocaine exposure. Invalid controls undermine conclusions of FDA studies. Acute kidney injury associated with smoking synthetic cannabinoid. Health care worker exposures to the antibacterial agent triclosan. J Occup Environ Med. Comprehensive analysis of 'bath salts' purchased from California stores and the internet. A case of rivaroxaban associated intracranial hemorrhage. West J Emerg Med. Armenian P , Gerona RR. A round robin approach to the analysis of bisphenol A BPA in human blood samples. Morbidity and mortality weekly report. Prolonged ventilatory failure and flaccid quadriparesis after ingestion of poison hemlock. Muscle Nerve. Cardiotoxicity in a citalopram and olanzapine overdose. Comment regarding the stability of active ingredients in long-expired prescription medications--reply. High times, low sats: diffuse pulmonary infiltrates associated with chronic synthetic cannabinoid use. Synthetic cannabinoid use associated with acute kidney injury. Morbidity and Mortality Weekly Report. A hour case of priapism from an over-the-counter herbal supplement. Ann Pharmacother. Stability of active ingredients in long-expired prescription medications. Arch Intern Med. Simultaneous detection of multiple designer drugs in serum, urine, and CSF in a patient with prolonged psychosis. Psychosis from a bath salt product containing flephedrone and MDPV with serum, urine, and product quantification. Bath salts. Clin Lab Med. Catecholaminergic polymorphic ventricular tachycardia found in an adolescent after a methylenedioxymethamphetamine and marijuana-induced cardiac arrest. Crit Care Med. Estimation of tamoxifen metabolite concentrations in the blood of breast cancer patients through CYP2D6 genotype activity score. Breast Cancer Res Treat. J Intensive Care Med. Confirmed glyburide poisoning from ingestion of 'street Valium'. Mol Biol Cell. Role of phosphoinositide signaling in the control of insulin exocytosis. Mol Endocrinol. J Biol Chem. This graph shows the total number of publications by year. To see the data as text, click here. To return to the graph, click here. This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine NLM classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. Start with: newest oldest Include: line numbers double spacing all authors publication IDs. Roy's Networks. Concepts Derived automatically from this person's publications. Co-Authors People in Profiles who have published with this person. Similar People People who share similar concepts with this person. Same Department. Home Contact us. Download vCard.

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Girona where can I buy cocaine

The Journal publishes articles on basic or clinical research relating to nephrology, arterial hypertension, dialysis and kidney transplants. It is governed by the peer review system and all original papers are subject to internal assessment and external reviews. The journal accepts submissions of articles in English and in Spanish languages. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Cocaine use is associated with multiple complications, the most common being cardiovascular and neurological disorders. Regular and continual use can lead to severe arterial hypertension AH and terminal chronic renal failure. We present the case of a year-old man, a habitual user of inhaled cocaine for 6 years, seen at the emergency department with dyspnoea on minimal exertion and headaches. Creatinine kinase levels were normal, and neither microhematuria nor proteinuria were found. The patient denied having taken cocaine in the last month due to his worsening general health, but a urine sample was not taken to rule it out. Haemodialysis was begun via a right jugular catheter with evident clinical improvement. Of note in his medical history were 2 admissions to another hospital. The first was 2. Doppler echocardiography showed severe concentric hypertrophy of the left ventricle and moderately depressed systolic function. The Doppler echocardiogram and catecholamine levels were normal. Kidney function recovered completely without dialysis. The second admission, 6 months before this one, was due to chest pain after consuming cocaine; the level of troponin enzymes was normal, but level of plasma creatinine of 2. Therefore, the patient continued to take irbesartan, amlodipine, carvedilol, and torsemide to control his blood pressure. Later, the patient stopped having medical check-ups. The medium and small-sized arteries showed significant lumen reduction with hyalinization of the intima and media, and intimal proliferation Figure 1. Immunofluorescence was negative. The most common kidney complications due to cocaine abuse are rhabdomyolysis or severe AHT. This triggers tissue hypoxia with myocytic necrosis, direct muscle toxicity, hyperpyrexia, and an increase in muscle activity with repeated trauma due to the agitation after consumption. This is the first case in our hospital of chronic kidney failure with the need for replacement therapy due to cocaine use. He also suffered from heart disease in the form of severe hypertrophy of the left ventricle with a depressed ejection fraction; a pathology described in and related with cocaine consumption. Besides, cocaine is known to lead to ischaemic cardiomyopathy in the form of angina pectoris, acute myocardial infarction, and episodes of cardiac arrest due to arrhythmias, even occurring in sporadic or one-off cocaine users. As nephrologists, it is necessary to understand the extensive range of diseases that cocaine can produce in the kidneys, taking into consideration its high, ever-increasing rates of consumption. Figure 1. Arteries with significant lumen reduction due to the hyalinization and proliferation of the intima and media. ISSN: Previous article Next article. November Pages More article options. DOI: Cocaine use, high blood pressure and chronic kidney disease. Sans Lorman b. Hospital de Figueres, Figueres, Girona. This item has received. Article information. Full Text. To the Editor, Cocaine use is associated with multiple complications, the most common being cardiovascular and neurological disorders. Nefrologia ; Cocaine use and kidney damage. Nephrol Dial Transplant ; Severe renal arterio-arteriolosclerosis after cocaine use. Am J Kidney Dis ;38 3 Clin J Am Soc Nephrol ; Cocaine-induced acute renal failure without rhabdomyolysis. Cardiovascular complications of cocaine use. N Engl J Med ; 5 Subscribe to our newsletter. Print Send to a friend Export reference Mendeley Statistics. This work is licensed under a Creative Commons Attribution 4. Instructions for authors Submit an article Ethics in publishing Language Editing services. Article options. Are you a health professional able to prescribe or dispense drugs?

Girona where can I buy cocaine