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26 juil. 2024 · We show a steep and near-complete replacement of circulating variants with Delta between May and August 2024 in metropolitan New York. We observed an increase of the Delta sublineage AY.25 (14% in vaccinated, 7% in unvaccinated), its spike mutation S112L, and AY.44 (8% in vaccinated, 2% in unvaccinated) with its nsp12 mutation F192V. 18 janv. 2024 · It demonstrates the urgency and importance of sustained investment in genomic surveillance strategies to timely identify the emergence of any potential viral pathogen or associated variants, which in turn is key to epidemic and pandemic preparedness. Keywords: SARS-CoV-2, Viral evolution, Genomic surveillance, Epidemic-pandemic preparedness Go to:. 15 sept. 2024 · In the case of SARS-CoV-2 in Africa, this means extending the geographic coverage of sequencing capacity to capture the dynamic genomic epidemiology in as many locations as possible. In a meta-analysis of the first 10,000 SARS-CoV-2 sequences generated in 2024 from Africa ( 15 ), several blind spots were identified with regard to genomic surveillance on the continent. 10 oct. 2024 · The transition from Delta variant to Omicron was characterized by a disappearance of viruses with mutations in the N-terminal domain (NTD) region (E156del, F157del, and R158G), and an appearance. 21 juil. 2024 · Genomic surveillance is important for pandemic preparedness. By deep sequencing of wastewater samples, we monitored the genetic dynamics of circulating SARS-CoV-2 virus variants in Austria from. 22 juil. 2024 · The novel respiratory disease COVID-19 has reached the status of worldwide pandemic and large efforts are currently being undertaken in molecularly characterizing the virus causing it, SARS-CoV-2. The genomic variability of SARS-CoV-2 specimens scattered across the globe can underly geographically specific etiological effects. In the present study, we gather the 48,635 SARS-CoV-2 complete. 28 mars 2024 · In this study, we aimed to investigate the global diversity of SARS-CoV-2 genomic surveillance, the global distribution, properties and extent of public availability of genomes. In addition, we. 6 mars 2024 · Our results provide a comprehensive view of the genomic epidemiology of SARS-CoV-2during the first 25 months into the pandemic in Mozambique, and highlighting the prevalence of VOCs Beta, Delta, and Omicron during the second, third, and fourth waves. Data from this study shows that first imports and exports of SARS-CoV-2 in Mozambique were from South Africa and to North America, both in March. 11 avr. 2024 · The SARS-CoV-2 variants of concern (VOCs) Delta and Omicron spread globally during mid and late 2024, respectively. In this study, we compare the dissemination dynamics of these VOCs in the. 16 juin 2024 · Here, we investigated the potential drivers of the surge by genomic analysis of 1056 SARS-CoV-2 positive samples collected in Seychelles between 14 March 2024 and 31 December 2024. The Seychelles genomes were classified into 32 Pango lineages, 1042 of which fell within four variants of concern, i.e., Alpha, Beta, Delta and Omicron. Abstract. Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million fatalities and the daily number of people infected increasing rapidly. Here we describe the currently available data on the emergence of the SARS-CoV-2. 1 juin 2024 · COVID-19 resulted in extensive morbidity and mortality worldwide. SARS-CoV-2 evolved rapidly, with increasing transmission due to Variants of Concern (VOC). Identifying VOC became important but genome submissions from low-middle income countries (LMIC) remained low leading to gaps in genomic epidemiology. We demonstrate the use of a specific mutation RT-PCR based approach to identify VOC in. 1 août 2024 · During December, 2019 to January, 2024 about 7540558 whole genome of SARS-CoV-2 were traced worldwide. Four variants of concern including beta, gamma, delta and omicron with their probable transmission history were indicated by four different color lines. Star and circle indicated probable origin places. Nature Communications (Jul 2024) . Genomic epidemiology of Delta SARS-CoV-2 during transition from elimination to suppression in Aotearoa New Zealand. 18 juil. 2024 · The bioinformatics method COJAC enables improved population-level surveillance of the emergence and spread of SARS-CoV-2 variants in wastewater. 21 sept. 2024 · Abstract. The use of real-time genomic epidemiology has enabled the tracking of the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), informing evidence-based public. 12 juil. 2024 · This incursion resulted in the largest outbreak seen in New Zealand caused by the Delta Variant of Concern. Here we generated 3806 high quality SARS-CoV-2 genomes from cases reported in New Zealand between 17 August and 1 December 2024, representing 43% of reported cases. We detected wide geographical spread coupled with undetected community. 11 nov. 2024 · Overall, the genomic and epidemiological data were most consistent with the hypothesis that a new variant with higher infectivity, Delta, was driving the unexpected overwhelming surge in Delhi. Recent in vitro data supports the possibility of a higher replication rate for Delta, thereby explaining potentially higher viral loads in RT-PCR data. 26 juil. 2024 · We show a steep and near-complete replacement of circulating variants with Delta between May and August 2024 in metropolitan New York. We observed an increase of the Delta sublineage AY.25 (14% in vaccinated, 7% in unvaccinated), its spike mutation S112L, and AY.44 (8% in vaccinated, 2% in unvaccinated) with its nsp12 mutation F192V in. 1 avr. 2024 · Abstract The spread of SARS-CoV-2 created a pandemic crisis with > 150,000 cumulative cases in > 65 countries within a few months. The reproductive number (R) is a metric to estimate the. 1 avr. 2024 · Abstract. The spread of SARS-CoV-2 created a pandemic crisis with > 150,000 cumulative cases in > 65 countries within a few months. The reproductive number (R) is a metric to estimate the transmission of a pathogen during an outbreak. Preliminary published estimates were based on the initial outbreak in China. This analysis led to further validation that genomic variation was occurring even during lockdown that was aimed at reducing the outbreak and was predictive of recurring surges in infections using > 20,000 genomes (Fig. 5). Low numbers of new cases were observed (Fig. 5 inset) was associated with a variable GENI score (February 2024). As the. Analysis of SARS‑CoV‑2 genomic epidemiology reveals disease transmission coupled to variant emergence and allelic variation D J Darwin R. Bandoy1,2& Bart C. Weimer 1* The spread of. 8 déc. 2024 · Genomic surveillance of SARS-CoV-2 reveals highest severity and mortality of delta over other variants: evidence from Cameroon Joseph Fokam, Rene Ghislain Essomba, Richard Njouom, Marie-Claire. 18 janv. 2024 · Abstract. The COVID-19 pandemic has brought significant challenges for genomic surveillance strategies in public health systems worldwide. During the past thirty-four months, many countries faced several epidemic waves of SARS-CoV-2 infections, driven mainly by the emergence and spread of novel variants. In that line, genomic surveillance has. Epidemiological analysis confirmed that early introductions of SARS-CoV-2 originated from mainland Europe (the majority from Italy and Spain). We identified subsequent early outbreaks in the community, within healthcare facilities and at an international conference. 14 oct. 2024 · Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India. Science 374, 995-999 (2024). DOI:10.1126/science.abj9932. 11 nov. 2024 · A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology. Nat. Microbiol. 5, 1403–1407 (2024). 10.1038/s41564-020-0770-5 [PMC free article] [Google Scholar]. 3 juin 2024 · Abstract. In April 2024, after successfully enduring three waves of the SARS-CoV2 pandemic in 2024, and having reached population seropositivity of about 50%, Delhi, the national capital of India was overwhelmed by the fourth wave. Here, we trace viral, host, and social factors contributing to the scale and exponent of the fourth.