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PLoS Genet

v.8(9); 2012 Sep

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PLoS Genet. 2012 Sep; 8(9): e1002962.
Published online 2012 Sep 27. doi: 10.1371/journal.pgen.1002962
Find articles by Irina Z. Plyusnina
Find articles by Rafael Villafuerte
1 Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
2 Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
3 CAS–MPG Partner Institute for Computational Biology SIBS, Shanghai, China
4 CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Vairão, Portugal
5 Departamento de Zoologia e Antropologia–Faculdade de Ciências da Universidade do Porto, Porto, Portugal
6 Fernan Vaz Gorilla Project, Port-Gentil, Gabon
7 Department of Biology, University of Turku, Turku, Finland
8 Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC, UCLM, JCCM), Ciudad Real, Spain
9 Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
10 Department of Behavioural Biology, University of Münster, Münster, Germany
11 IFM Biology, Division of Zoology, Avian Behaviour Genomics and Physiology Group, Linköping University, Linköping, Sweden
University of Washington, United States of America
The authors have declared that no competing interests exist.
Received 2012 Apr 23; Accepted 2012 Aug 6.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
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1 variance explained by domestication/species, mean across expressed genes.
2 absolute fold change, mean across expressed genes.
3 Fraction of all possible permutations of the domestication factor where the respective statistic is matched or exceeded.
1 SNVs where both alleles segregate in both the domesticated and the wild animals.
2 Because the guinea pig genome is not assembled into chromosomes, these data include X-chromosomal sequences.
3 domesticated (tame)/wild (aggressive).
Pairwise overlap of DE genes among domestication events.
Above diagonal: number of genes that are DE in both species, with Fisher's exact test p-values.
Below diagonal: Odds ratios of FET testing if DE genes in the one species predict expression direction in the other species, with Fisher's exact test p-values. Only the more significant direction is shown (see Materials and Methods for details).
Pairwise correlations between expression differences among domestication events.
Shown are correlations (Spearman's rho) of median expression differences between domesticated and wild animals across all expressed orthologues, with permutation-based p-values.
Gene expression across domesticated animals.
1 p-values are the fraction of 1,000 random permutations of the corresponding factor where the observed statistic is matched or exceeded.
2 number of genes with nominally significant (per-gene ANOVA p<0.05) effect for the domestication factor and with the same direction of expression change in the domesticated species. VSD: variance-stabilized data.
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Галерея 2645576
У похотливой женщины из Аризоны большая коллекция дилдо
Трахнул красивую в рот и в пизду

Галерея 3459979

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