Галерея 3345031
⚡ ПОДРОБНЕЕ ЖМИТЕ ЗДЕСЬ 👈🏻👈🏻👈🏻
Галерея 3345031
Tema:
Idioma:
afar
abjasio (o abjasiano)
avéstico
afrikáans
akano
amhárico
aragonés
árabe
asamés
asturiano
Athabascan
avar (o ávaro)
aimara
azerí
baskir
bielorruso
búlgaro
bhoyapurí
bislama
bambara
bengalí
tibetano
bretón
bosnio
catalán
checheno
chamorro
corso
cree
checo
eslavo eclesiástico antiguo
chuvasio
galés
danés
alemán
maldivo (o dhivehi)
dzongkha
ewé
griego (moderno)
inglés
esperanto
español (o castellano)
estonio
euskera
persa
fula
finés (o finlandés)
fiyiano (o fiyi)
feroés
francés
frisón (o frisio)
irlandés (o gaélico)
gaélico escocés
gallego
guaraní
guyaratí (o guyaratí)
manés (gaélico manés o de Isla de Man)
hausa
hebreo
hindi (o hindú)
hiri motu
croata
haitiano
húngaro
armenio
herero
interlingua
indonesio
occidental
igbo
yi de Sichuán
iñupiaq
ido
islandés
italiano
inuktitut (o inuit)
japonés
javanés
georgiano
Karakalpak
kongo (o kikongo)
kikuyu
kuanyama
kazajo (o kazajio)
groenlandés (o kalaallisut)
camboyano (o jemer)
canarés
coreano
kanuri
cachemiro (o cachemir)
kurdo
komi
córnico
kirguís
latín
luxemburgués
luganda
limburgués
lingala
lao
lituano
luba-katanga (o chiluba)
letón
malgache (o malagasy)
marshalés
maorí
macedonio
malayalam
mongol
maratí
malayo
maltés
birmano
nauruano
noruego bokmål
ndebele del norte
nepalí
ndonga
neerlandés (u holandés)
nynorsk
noruego
ndebele del sur
navajo
chichewa
occitano
ojibwa
oromo
oriya
osético (u osetio, u oseta)
panyabí (o penyabi)
pali
polaco
pastú (o pastún, o pashto)
portugués
quechua
romanche
kirundi
rumano
ruso
ruandés (o kiñaruanda)
sánscrito
sardo
sindhi
sami septentrional
sango
cingalés
eslovaco
esloveno
samoano
shona
somalí
albanés
serbio
suazi (o swati, o siSwati)
sesotho
sundanés (o sondanés)
sueco
suajili
tamil
télugu
tayiko
tailandés
tigriña
turcomano
tagalo
setsuana
tongano
turco
tsonga
tártaro
twi
tahitiano
uigur
ucraniano
urdu
uzbeko
valenciano
venda
vietnamita
volapük
valón
wolof
xhosa
yídish (o yidis, o yiddish)
yoruba
chuan (o chuang, o zhuang)
chino
zulú
Asignatura:
Curso/nivel:
Edad:
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18+
Buscar:
Todas las fichas
Sólo de usuarios que sigo
Sólo mis fichas favoritas
Sólo mis propias fichas
Introduce tu nombre completo:
Curso/grupo:
Asignatura:
Introduce el email o código clave de tu profesor/a:
Términos y condiciones
Política de privacidad
Configuración de cookies
Denunciar infracción de copyright
Contacto
Por favor, permite el acceso al micrófono
Mira en la parte alta de tu navegador. Si ves un mensaje pidiendo tu permiso para acceder al micrófono, por favor permítelo.
Cerrar
ID: 3345031
Idioma: inglés
Asignatura: Physical Education (PE)
Curso/nivel: GRADE 3
Edad: 7-10
Tema principal: Vocabulary pe
Otros contenidos:
Añadir a mis cuadernos (0)
Descargar archivo pdf
Insertar en mi web o blog
Añadir a Google Classroom
Añadir a Microsoft Teams
Compartir por Whatsapp
Enviar mis respuestas a mi profesor/a
Дополнительная информация: SSL_ERROR_NO_CYPHER_OVERLAP
Владелец www.pinkbike.com неправильно настроил свой веб-сайт. Чтобы защитить вашу информацию от кражи, Firefox не соединился с этим веб-сайтом.
Отправка сообщений о подобных ошибках поможет Mozilla обнаружить и заблокировать вредоносные сайты
Сообщить
Попробовать снова
Отправка сообщения
Сообщение отправлено
использует защитную технологию, которая является устаревшей и уязвимой для атаки. Злоумышленник может легко выявить информацию, которая, как вы думали, находится в безопасности.
Dashboard
Publications
Account settings
Log out
Journal List
PLoS One
PMC3345031
Create a new collection
Add to an existing collection
Unable to load your collection due to an error
Please try again
Published online 2012 May 4. doi: 10.1371/journal.pone.0035863
Find articles by Kathleen C. Barnes
1
Department of Epidemiology, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, United States of America
2
Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America
3
Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Salvador, Bahia, Brazil
4
Programa para o Controle da Asma e Rinite Alérgica na Bahia, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil
Received 2011 Oct 19; Accepted 2012 Mar 27.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
The 7 IL13 SNPs among 222 founders in the Brazilian study sample.
Abbreviations: SNP, single-nucleotide polymorphism; UTR, untranslated region; MAF, minor allele frequency; Chr, chromosome. Chromosomal position according to db126; major and minor alleles in Brazilian data before and after forward slash, respectively; ancestral allele according to db126 data underlined. Atopy-related SNPs are indicated in bold and tagging SNPs that are not atopy-related are in regular font.
Generalized Estimating Equation association tests for individual SNPs with tIgE levels (N = 572) and Schistosoma mansoni egg counts (N = 397) under the additive model.
Abbreviations: Dir, direction of association; pos, positive; neg, negative.
a log(10)-transformed values adjusted for age, sex, smoking, and helminthic infection status.
b log(10)-transformed values adjusted for age, sex, and low, medium and high exposure to infested water sources.
c P-values and direction of association with high values are given for the beta-coefficient for the minor allele under the additive model.
d P-values are statistically significant with α = 0.05 for atopy-related SNPs (bold) and α = 0.005 for tagging SNPs that are not atopy-related (unbolded).
QTDT association results for individual IL13 SNPs with tIgE levels and Schistosoma mansoni egg count.
Abbreviations: Dir, direction of association; pos, positive; neg, negative; N offspring, number of informative offspring over number of offspring evaluated; neg., negative; pos., positive; QTDT, quantitative transmission disequilibrium test; S.m. count, Schistosoma mansoni egg count per gram of fecal matter; SNP, single-nucleotide polymorphism; tIgE, total serum IgE.
a log(10)-transformed values adjusted for age, sex, smoking, and helminthic infection status.
b log(10)-transformed values adjusted for age, sex, and low, medium and high exposure to infested water sources.
c Likelihood ratio tests were compared to obtain tests of evidence of association in the presence of linkage for models where (1) means were considered as composed of covariate effects and between- and within-family components and (2) means were considered as composed of covariate effects and between-family components only. For both models, the variance was set to be composed of polygenic and individual environmental effects.
d P-values are statistically significant with α = 0.05 for atopy-related SNPs (bold) and α = 0.005 for tagging SNPs that are not atopy-related (unbolded).
1. King CH, Dickman K, Tisch DJ. Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet; 2005; 365 :1561–9. [ PubMed ] [ Google Scholar ]
2. Pearce EJ, MacDonald AS. The immunobiology of schistosomiasis. Nat Rev Immunol; 2002; 2 :499–511. [ PubMed ] [ Google Scholar ]
3. Bethony JM, Quinnell RJ. Genetic epidemiology of human schistosomiasis in Brazil. Acta Trop; 2008; 108 :166–74. [ PubMed ] [ Google Scholar ]
4. Quinnell RJ. Genetics of susceptibility to human helminth infection. Int J Parasitol; 2003; 33 :1219–31. [ PubMed ] [ Google Scholar ]
5. Caldas IR, Campi-Azevedo AC, Oliveira LF, Silveira AM, Oliveira RC, et al. Human schistosomiasis mansoni: immune responses during acute and chronic phases of the infection. Acta Trop; 2008; 108 :109–17. [ PubMed ] [ Google Scholar ]
6. Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD. Interleukin-4 and interleukin-13 signaling connections maps. Science; 2003; 300 :1527–8. [ PubMed ] [ Google Scholar ]
7. Vercelli D. Genetics of IL-13 and functional relevance of IL-13 variants. Curr Opin Allergy Clin Immunol; 2002; 2 :389–93. [ PubMed ] [ Google Scholar ]
8. Ober C, Hoffjan S. Asthma genetics 2006: the long and winding road to gene discovery Genes Immun; 2006; 7 :95–100. [ PubMed ] [ Google Scholar ]
9. Meyers DA, Beaty TH, Colyer CR, Marsh DG. Genetics of total serum IgE levels: a regressive model approach to segregation analysis. Genet Epidemiol; 1991; 8 :351–9. [ PubMed ] [ Google Scholar ]
10. Gerrard JW, Rao DC, Morton NE. A genetic study of immunoglobulin E. Am J Hum Genet; 1978; 30 :46–58. [ PMC free article ] [ PubMed ] [ Google Scholar ]
11. Grant AV, Araujo MI, Ponte EV, Oliveira RR, Cruz AA, et al. High heritability but uncertain mode of inheritance for total serum IgE level and Schistosoma mansoni infection intensity in a schistosomiasis-endemic Brazilian population. J Infect Dis; 2008; 198 :1227–36. [ PubMed ] [ Google Scholar ]
12. Hoffjan S, Ober C. Present status on the genetic studies of asthma. Curr Opin Immunol; 2002; 14 :709–17. [ PubMed ] [ Google Scholar ]
13. Marquet S, Abel L, Hillaire D, Dessein H, Kalil J, et al. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet; 1996; 14 :181–4. [ PubMed ] [ Google Scholar ]
14. Muller-Myhsok B, Stelma FF, Guisse-Sow F, Muntau B, Thye T, et al. Further evidence suggesting the presence of a locus, on human chromosome 5q31-q33, influencing the intensity of infection with Schistosoma mansoni. Am J Hum Genet; 1997; 61 :452–4. [ PMC free article ] [ PubMed ] [ Google Scholar ]
15. van der Pouw Kraan TC, van Veen A, Boeije LC, van Tuyl SA, de Groot ER, et al. An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immun; 1999; 1 :61–5. [ PubMed ] [ Google Scholar ]
16. Cameron L, Webster RB, Strempel JM, Kiesler P, Kabesch M, et al. Th2 cell-selective enhancement of human IL13 transcription by IL13–1112C>T, a polymorphism associated with allergic inflammation. J Immunol; 2006; 177 :8633–42. [ PubMed ] [ Google Scholar ]
17. Arima K, Umeshita-Suyama R, Sakata Y, Akaiwa M, Mao XQ, et al. Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma. J Allergy Clin Immunol; 2002; 109 :980–7. [ PubMed ] [ Google Scholar ]
18. Kouriba B, Chevillard C, Bream JH, Argiro L, Dessein H, et al. Analysis of the 5q31-q33 locus shows an association between IL13–1055C/T IL-13–591A/G polymorphisms and Schistosoma haematobium infections. J Immunol; 2005; 174 :6274–81. [ PubMed ] [ Google Scholar ]
19. Gatlin MR, Black CL, Mwinzi PN, Secor WE, Karanja DM, et al. Association of the gene polymorphisms IFN-gamma +874, IL-13–1055 and IL-4–590 with patterns of reinfection with Schistosoma mansoni. PLoS Negl Trop Dis; 2009; 3 :e375. [ PMC free article ] [ PubMed ] [ Google Scholar ]
20. Katz N, Zicker F, RS Rocha RS, VB Oiveira VB. Reinfection of patients in schistosomiasis mansoni endemic areas after specific treatment. Revista do Instituto de Medicina Tropical de Sao Paulo; 1978; 20 :273–8. [ PubMed ] [ Google Scholar ]
21. Katz N, Coelho PM, Pellegrino J. Evaluation of Kato’s quantitative method through the recovery of Schistosoma mansoni eggs added to human feces. Journal of Parasitology; 1970; 56 :1032–3. [ PubMed ] [ Google Scholar ]
22. Tarazona-Santos E, Tishkoff SA. Divergent patterns of linkage disequilibrium and haplotype structure across global populations at the interleukin-13 (IL13) locus. Genes Immun; 2005; 6 :53–65. [ PubMed ] [ Google Scholar ]
23. Azevedo ES. Subgroup studies of black admixture within a mixed population of Bahia, Brazil. Ann Hum Genet; 44(Pt. 1980; 1) :55–60. [ PubMed ] [ Google Scholar ]
24. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics; 1986; 42 :121–30. [ PubMed ] [ Google Scholar ]
25. Abecasis GR, Cookson WO, Cardon LR. Pedigree tests of transmission disequilibrium. Eur J Hum Genet; 2000; 8 :545–51. [ PubMed ] [ Google Scholar ]
26. Abecasis GR, Cardon LR, Cookson WO. A general test of association for quantitative traits in nuclear families. Am J Hum Genet; 2000; 66 :279–92. [ PMC free article ] [ PubMed ] [ Google Scholar ]
27. Grant AV, Araujo MI, Ponte EV, Oliveira RR, Cruz AA, et al. Polymorphisms in IL10 are associated with total Immunoglobulin E levels and Schistosoma mansoni infection intensity in a Brazilian population. Genes Immun; 2011; 12 :46–50. [ PubMed ] [ Google Scholar ]
28. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, et al. The structure of haplotype blocks in the human genome. Science; 2002; 296 (5576):2225–9. [ PubMed ] [ Google Scholar ]
29. Gauderman WJ. Sample size requirements for matched case-control studies of gene-environment interaction. Stat Med; 2002; 21 :35–50. [ PubMed ] [ Google Scholar ]
30. Isnard A, Kouriba B, Doumbo O, Chevilla
В 65 лет она продолжает ебаться как кошка
Отдых на море с подружкой
Прекрасная девушка в красивом коротеньком платье красного цвета