Галерея 2671951

Галерея 2671951

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Neuropsychiatr Dis Treat

v.2(4); 2006 Dec

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Neuropsychiatr Dis Treat. 2006 Dec; 2(4): 445–453.
1 Center for Drug and Alcohol Programs, Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Charleston, SC, USA;
2 Ralph H. Johnson Department of Veteran Affairs Medical Center, Research and Development Services, Charleston, SC, USA
Correspondence: Tara Wright, Medical University of South Carolina, Institute of Psychiatry 5N, 67 President Street, Charleston, SC, 29425, USA, Tel +1 843 792 2727, Fax +1 843 792 5728, Email
ude.csum@thgirw
Copyright © 2006 Dove Medical Press Limited. All rights reserved
Keywords: acamprosate, alcohol, alcohol dependence, abstinence
a Forest Pharmaceuticals, Inc. 2005
b RiVea (naltrexone hydrochloride) Tablets patient package insert ( Mallinckrodt 2005 ).
c Antabuse (disulfiram) Tablets patient package insert ( Odyssey Pharmaceuticals, Inc. 2005 ).
Anonymous Acamprosate (Campral) for alcoholism. Med Lett Drugs Ther. 2005; 47 :1–3. [ PubMed ] [ Google Scholar ] [APA] American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994. [ Google Scholar ] Bachteler D, Economidou D, Danysz W, et al. The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat. Neuropsychopharmacology. 2005; 30 :1104–10. [ PubMed ] [ Google Scholar ] Besson J, Aeby F, Kasas A, et al. Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study. Alcohol Clin Exp Res. 1998; 22 :573–9. [ PubMed ] [ Google Scholar ] Boeijinga PH, Parot P, Soufflet L, et al. Pharmacodynamic effects of acamprosate on markers of cerebral function in alcohol-dependent subjects administered as pretreatment and during alcohol abstinence. Neuropsychobiology. 2004; 50 :71–7. [ PubMed ] [ Google Scholar ] Boismare F, Daoust M, Moore N, et al. A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved? Pharmacol Biochem Behav. 1984; 21 :787–9. [ PubMed ] [ Google Scholar ] Bouza C, Angeles M, Munoz A, et al. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction. 2004; 99 :811–28. [ PubMed ] [ Google Scholar ] Chick J, Howlett H, Morgan MY, et al. United Kingdom Multicentre Acamprosate Study (UKMAS): a 6-month prospective study of acamprosate versus placebo in preventing relapse after withdrawal from alcohol. Alcohol Alcohol. 2000; 35 :176–87. [ PubMed ] [ Google Scholar ] Czachowski CL, Legg BH, Samson HH. Effects of acamprosate on ethanol-seeking and self-administration in the rat. Alcohol Clin Exp Res. 2001; 25 :344–50. [ PubMed ] [ Google Scholar ] Dahchour A, De Witte P. Ethanol and amino acids in the central nervous system: assessment of the pharmacological actions of acamprosate. Prog Neurobiol. 2000; 60 :343–62. [ PubMed ] [ Google Scholar ] De Sousa A, De Sousa A. An open randomized study comparing disulfiram and acamprosate in the treatment of alcohol dependence. Alcohol Alcohol. 2005; 40 :545–8. [ PubMed ] [ Google Scholar ] Durbin P, Hulot T, Chabac S. In: Soyka M, editor. Pharmacodynamics and pharmacokinetics of acamprosate: an overview; Acamprosate in relapse prevention of alcoholism; Proceedings of the 1st Campral-symposium ESBRA; Stuttgart, Germany: Springer. 1995. pp. 47–64. [ Google Scholar ] Forest Pharmaceuticals Inc 2005. CAMPRAL (acamprosate calcium) delayed-release tablets prescribing information [online]. Accessed 20 June 2006. URL: http://www.campral.com Garbutt JC, West SL, Carey TS, et al. Pharmacological treatment of alcohol dependence: A review of the evidence. JAMA. 1999; 281 :1318–25. 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URL: http://www.pharmaceuticals.mallinckrodt.com/Products/Product.asp?ProductID=5406 Mann K, Lehert K, Morgan M. The efficacy of acamprosate in the maintenance of abstinence in alcohol-dependent individuals: results of a meta-analysis. Alcohol Clin Exp Res. 2004; 28 :51–63. [ PubMed ] [ Google Scholar ] Monterosso JR, Flannery BA, Pettinati HM, et al. Predicting treatment response to naltrexone: the influence of craving and family history. Am J Addict. 2001; 10 :258–68. [ PubMed ] [ Google Scholar ] Odyssey Pharmaceuticals, Inc 2005. Antabuse (disulfiram) Tablets patient package insert [online]. Accessed on 21 October 2005. URL: http://www.odysseypharm.com/productTable.asp?id=16 Olive MF, Nannini MA, Ou CJ, et al. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. Eur J Pharmacol. 2002; 437 :55–61. [ PubMed ] [ Google Scholar ] Paille FM, Guelfi JD, Perkins AC, et al. Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol. 1995; 30 :239–47. [ PubMed ] [ Google Scholar ] Palmer AJ, Neeser K, Weiss C, et al. The long-term cost-effectiveness of improving alcohol abstinence with adjunctive acamprosate. Alcohol Alcohol. 2000; 35 :478–92. [ PubMed ] [ Google Scholar ] Pelc I, Verbanck P, Le Bon O, et al. Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients. A 90-day placebo-controlled dose-finding study. Br J Psychiatry. 1997; 171 :73–7. [ PubMed ] [ Google Scholar ] Poldrugo F, Haeger DA, Comte S, et al. A critical review of pharmacoeconomic studies of acamprosate. Alcohol Alcohol. 2005; 40 :422–30. [ PubMed ] [ Google Scholar ] Rivara FP, Garrison MM, Ebel B, et al. Mortality attributable to harmful drinking in the United States, 2000. J Stud Alcohol. 2004; 65 :530–6. [ PubMed ] [ Google Scholar ] Rubio G, Jimenez-Arriero MA, Ponce G, et al. Naltrexone versus acamprosate: one year follow-up of alcohol dependence treatment. Alcohol Alcohol. 2001; 36 :419–25. [ PubMed ] [ Google Scholar ] Rychlik R, Siedentop H, Pfeil T, et al. Cost-effectiveness of adjuvant treatment with acamprosate in maintaining abstinence in alcohol dependent patients. Eur Addict Res. 2003; 9 :59–64. [ PubMed ] [ Google Scholar ] Saivin S, Hulot T, Chabac S, et al. Clinical pharmacokinetics of acamprosate. Clin Pharmacokinet. 1998; 35 :331–45. [ PubMed ] [ Google Scholar ] Sass H, Sokya M, Mann K, et al. Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry. 1996; 53 :673–80. [ PubMed ] [ Google Scholar ] Scott LJ, Figgitt DP, Keam SJ, et al. Acamprosate: A review of its use in the maintenance of abstinence in patients with alcohol dependence. CNS Drugs. 2005; 19 :445–64. [ PubMed ] [ Google Scholar ] Shuckit M, Tapert S. Alcohol. In: Galanter M, Kleber HD, editors. Textbook of substance abuse treatment. 3rd ed. Washington DC: American Psychiatric Publishing, Inc; 2004. pp. 151–166. [ Google Scholar ] Sinclair JD. Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism. Alcohol Alcohol. 2001; 36 :2–10. [ PubMed ] [ Google Scholar ] Spanagel R, Holter SM, Allingham K, et al. Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur J Pharmacol. 1996; 305 :39–44. [ PubMed ] [ Google Scholar ] Substance Abuse and Mental Health Services Administration . Summary of National Findings. Vol. 1. Rockville, MD: Dept of Health and Human Services; 2002. Results from the 2001 National Household Survey of Drug Abuse. [ Google Scholar ] Streeton C, Whelan G. Naltrexone, a relapse prevention maintenance treatment of alcohol dependence: a meta-analysis of randomized controlled trials. Alcohol Alcohol. 2001; 36 :544–52. 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Articles from Neuropsychiatric Disease and Treatment are provided here courtesy of Dove Press
[APA] American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994. [ Google Scholar ] [ Ref list ]
Grant BF, Dawson DA, Stinson FS, et al. The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991–1992 and 2001–2002. Drug Alcohol Depend. 2004; 74 :223–34. [ PubMed ] [ Google Scholar ] [ Ref list ]
Rivara FP, Garrison MM, Ebel B, et al. Mortality attributable to harmful drinking in the United States, 2000. J Stud Alcohol. 2004; 65 :530–6. [ PubMed ] [ Google Scholar ] [ Ref list ]
US Department of Health and Human Services . Tenth Special Report to Congress on Alcohol and Health. Bethesda, MD: US Dept of Health and Human Services; 2000. [ Google Scholar ] [ Ref list ]
Walker RD, Howard MO, Lambert MD, et al. Psychiatric and medical comorbidities of veterans with substance use disorders. Hosp Community Psychiatry. 1994; 45 :232–7. [ PubMed ] [ Google Scholar ] [ Ref list ]
Substance Abuse and Mental Health Services Administration . Summary of National Findings. Vol. 1. Rockville, MD: Dept of Health and Human Services; 2002. Results from the 2001 National Household Survey of Drug Abuse. [ Google Scholar ] [ Ref list ]
Whitworth AB, Fischer F, Lesch OM, et al. Comparison of acamprosate and placebo and long-term treatment of alcohol dependence. Lancet. 1996; 347 :1438–42. [ PubMed ] [ Google Scholar ] [ Ref list ]
Shuckit M, Tapert S. Alcohol. In: Galanter M, Kleber HD, editors. Textbook of substance abuse treatment. 3rd ed. Washington DC: American Psychiatric Publishing, Inc; 2004. pp. 151–166. [ Google Scholar ] [ Ref list ]
Sinclair JD. Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism. Alcohol Alcohol. 2001; 36 :2–10. [ PubMed ] [ Google Scholar ] [ Ref list ]
Wilde MI, Wagstaff AJ. Acamprosate. A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification. Drugs. 1997; 53 :1038–53. [ PubMed ] [ Google Scholar ] [ Ref list ]
Forest Pharmaceuticals Inc 2005. CAMPRAL (acamprosate calcium) delayed-release tablets prescribing information [online]. Accessed 20 June 2006. URL: http://www.campral.com [ Ref list ]
Littleton J, Zieglgansberger W. Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence. Am J Addict. 2003; 12 (Suppl 1):S3–11. [ PubMed ] [ Google Scholar ] [ Ref list ]
Anonymous Acamprosate (Campral) for alcoholism. Med Lett Drugs Ther. 2005; 47 :1–3. [ PubMed ] [ Google Scholar ] [ Ref list ]
Littleton J. Acamprosate in alcohol dependence: How does it work? Addiction. 1995; 90 :1179–88. [ PubMed ] [ Google Scholar ] [ Ref list ]
Knopfel TH, Zeise ML, Cuenod M, et al. L-homocysteic acid but not L-glutamate is an endogenous N-methyl-D-aspartic acid receptor preferring agonist in rat neocortical neurons in vitro. Neurosci Lett. 1987; 81 :188–92. [ PubMed ] [ Google Scholar ] [ Ref list ]
Scott LJ, Figgitt DP, Keam SJ, et al. Acamprosate: A review of its use in the maintenance of abstinence in patients with alcohol dependence. CNS Drugs. 2005; 19 :445–64. [ PubMed ] [ Google Scholar ] [ Ref list ]
Ueno S, Harris RA, Messing RO, et al. Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior. Alcohol Clin Exp Res. 2001; 25 (Suppl 5):76S–81S. [ PubMed ] [ Google Scholar ] [ Ref list ]
Dahchour A, De Witte P. Ethanol and amino acids in the central nervous system: assessment of the pharmacological actions of acamprosate. Prog Neurobiol. 2000; 60 :343–62. [ PubMed ] [ Google Scholar ] [ Ref list ]
Boeijinga PH, Parot P, Soufflet L, et al. Pharmacodynamic effects of acamprosate on markers of cerebral function in alcohol-dependent subjects administered as pretreatment and during alcohol abstinence. Neuropsychobiology. 2004; 50 :71–7. [ PubMed ] [ Google Scholar ] [ Ref list ]
Saivin S, Hulot T, Chabac S, et al. Clinical pharmacokinetics of acamprosate. Clin Pharmacokinet. 1998; 35 :331–45. [ PubMed ] [ Google Scholar ] [ Ref list ]
Durbin P, Hulot T, Chabac S. In: Soyka M, editor. Pharmacodynamics and pharmacokinetics of acamprosate: an overview; Acamprosate in relapse prevention of alcoholism; Proceedings of the 1st Campral-symposium ESBRA; Stuttgart, Germany: Springer. 1995. pp. 47–64. [ Google Scholar ] [ Ref list ]
Bouza C, Angeles M, Munoz A, et al. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction. 2004; 99 :811–28. [ PubMed ] [ Google Scholar ] [ Ref list ]
Boismare F, Daoust M, Moore N, et al. A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved? Pharmacol Biochem Behav. 1984; 21 :787–9. [ PubMed ] [ Google Scholar ] [ Ref list ]
Gewiss M, Heidbreder C, Opsomer L, et al. Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour. Alcohol Alcohol. 1991; 26 :129–37. [ PubMed ] [ Google Scholar ] [ Ref list ]
Spanagel R, Holter SM, Allingham K, et al. Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur J Pharmacol. 1996; 305 :39–44. [ PubMed ] [ Google Scholar ] [ Ref list ]
Holter SM, Landgraf R, Zieglgansberger W, et al. Time course of acamprosate action on operant ethanol self-administration after ethanol deprivation. Alcohol Clin Exp Res. 1997; 21 :862–8. [ PubMed ] [ Google Scholar ] [ Ref list ]
Czachowski CL, Legg BH, Samson HH. Effects of acamprosate on ethanol-seeking and self-administration in the rat. Alcohol Clin Exp Res. 2001; 25 :344–50. [ PubMed ] [ Google Scholar ] [ Ref list ]
Olive MF, Nannini MA, Ou CJ, et al. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. Eur J Pharmacol. 2002; 437 :55–61. [ PubMed ] [ Google Scholar ] [ Ref list ]
Bachteler D, Economidou D, Danysz W, et al. The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat. Neuropsychopharmacology. 2005; 30 :1104–10. [ PubMed ] [ Google Scholar ] [ Ref list ]
Pelc I, Verbanck P, Le Bon O, et al. Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients. A 90-day placebo-controlled dose-finding study. Br J Psychiatry. 1997; 171 :73–7. [ PubMed ] [ Google Scholar ] [ Ref list ]
Sass H, Sokya M, Mann K, et al. Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry. 1996; 53 :673–80. [ PubMed ] [ Google Scholar ] [ Ref list ]
Paille FM, Guelfi JD, Perkins AC, et al. Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol. 1
Женщина в зрелом возрасте приходит к гинекологу чтобы подставить для осмотра свои отверстия
Трахает в жопу двух телок и кончает
Ее глаза полны похоти и страсти

Галерея 2671951

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