Галерея 2642532

Галерея 2642532

WIRTGEN

VÖGELE

HAMM

KLEEMANN

BENNINGHOVEN

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Affiliation

1 Department of Medicine, School of Medicine, University of New Mexico, Albuquerque 87131.

P Garcia-Peñarrubia et al.

J Exp Med .

1989 .

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1 Department of Medicine, School of Medicine, University of New Mexico, Albuquerque 87131.

Garcia-Peñarrubia P, Bankhurst AD, Koster FT.
Garcia-Peñarrubia P, et al.
J Immunol. 1989 Feb 15;142(4):1310-7.
J Immunol. 1989.

PMID: 2644352

Garcia-Peñarrubia P, Lennon MP, Koster FT, Kelley RO, Bankhurst AD.
Garcia-Peñarrubia P, et al.
Infect Immun. 1989 Jul;57(7):2057-65. doi: 10.1128/iai.57.7.2057-2065.1989.
Infect Immun. 1989.

PMID: 2731983
Free PMC article.

Kang YH, Carl M, Maheshwari RK, Watson LP, Yaffe L, Grimley PM.
Kang YH, et al.
Lab Invest. 1988 Feb;58(2):196-209.
Lab Invest. 1988.

PMID: 2448547

Schmidt S, Ullrich E, Bochennek K, Zimmermann SY, Lehrnbecher T.
Schmidt S, et al.
Expert Rev Hematol. 2016 Dec;9(12):1119-1127. doi: 10.1080/17474086.2016.1254546. Epub 2016 Nov 11.
Expert Rev Hematol. 2016.

PMID: 27791439

Review.

Babcock GF, Phillips JH.
Babcock GF, et al.
Surv Immunol Res. 1983;2(1):88-101. doi: 10.1007/BF02918399.
Surv Immunol Res. 1983.

PMID: 6359325

Review.

No abstract available.

Jahanbani F, Maynard RD, Sing JC, Jahanbani S, Perrino JJ, Spacek DV, Davis RW, Snyder MP.
Jahanbani F, et al.
PLoS One. 2022 Aug 9;17(8):e0272703. doi: 10.1371/journal.pone.0272703. eCollection 2022.
PLoS One. 2022.

PMID: 35943990
Free PMC article.

Elemam NM, Ramakrishnan RK, Hundt JE, Halwani R, Maghazachi AA, Hamid Q.
Elemam NM, et al.
Front Cell Infect Microbiol. 2021 Nov 5;11:733564. doi: 10.3389/fcimb.2021.733564. eCollection 2021.
Front Cell Infect Microbiol. 2021.

PMID: 34804991
Free PMC article.

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Khader SA, Divangahi M, Hanekom W, Hill PC, Maeurer M, Makar KW, Mayer-Barber KD, Mhlanga MM, Nemes E, Schlesinger LS, van Crevel R, Vankayalapati R(, Xavier RJ, Netea MG; Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18.
Khader SA, et al.
J Clin Invest. 2019 Sep 3;129(9):3482-3491. doi: 10.1172/JCI128877.
J Clin Invest. 2019.

PMID: 31478909
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Schmidt S, Tramsen L, Rais B, Ullrich E, Lehrnbecher T.
Schmidt S, et al.
Oncotarget. 2018 Apr 17;9(29):20891-20907. doi: 10.18632/oncotarget.25058. eCollection 2018 Apr 17.
Oncotarget. 2018.

PMID: 29755697
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Schmidt S, Tramsen L, Lehrnbecher T.
Schmidt S, et al.
Front Immunol. 2017 Nov 22;8:1623. doi: 10.3389/fimmu.2017.01623. eCollection 2017.
Front Immunol. 2017.

PMID: 29213274
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The in vitro effects of human NK cells on viability of Gram-negative and Gram-positive bacteria was investigated. PBLs depleted of glass-adherent cells showed a significant antibacterial activity that was increased as the concentration of NK cells became higher. Leu-11-enriched cells exhibited the most efficient bactericidal activity. Stimulation of NK cells with staphylococcal enterotoxin B for 16 h produced a significant increase in the antibacterial activity of all NK cells tested. The antibacterial activity of monocyte-depleted cells and Leu-11-enriched cells was also enhanced after culturing in vitro for 16-24 h without exogenous cytokines. Dependence of the antibacterial activity on the presence of serum in the culture medium was not found. Ultrastructural studies revealed close contact between NK cell membranes and bacteria, no evidence of phagocytosis, and extracellular bacterial ghosts, after incubation at 37 degrees C. Supernatants from purified NK cells exhibited potent bactericidal activity with kinetics and target specificity similar to that of effector cells. These results document the potent antibacterial activity of purified NK cells and suggest an extracellular mechanism of killing.

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