Галерея 1452807
Галерея 1452807
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Affiliation
1 Beth Israel Medical Center, Department of Dental Medicine, New York, NY 10003.
C Barr et al.
J Clin Periodontol .
1992 Nov .
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1 Beth Israel Medical Center, Department of Dental Medicine, New York, NY 10003.
Ndiaye CF, Critchlow CW, Leggott PJ, Kiviat NB, Ndoye I, Robertson PB, Georgas KN.
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Review.
Shaikh MS, Shahzad Z, Tash EA, Janjua OS, Khan MI, Zafar MS.
Shaikh MS, et al.
Cells. 2022 Mar 30;11(7):1168. doi: 10.3390/cells11071168.
Cells. 2022.
PMID: 35406732
Free PMC article.
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Butera A, Gallo S, Pascadopoli M, Maiorani C, Milone A, Alovisi M, Scribante A.
Butera A, et al.
Microorganisms. 2022 Feb 1;10(2):337. doi: 10.3390/microorganisms10020337.
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PMID: 35208792
Free PMC article.
Butera A, Gallo S, Pascadopoli M, Taccardi D, Scribante A.
Butera A, et al.
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Antibiotics (Basel). 2022.
PMID: 35052995
Free PMC article.
Butera A, Gallo S, Maiorani C, Molino D, Chiesa A, Preda C, Esposito F, Scribante A.
Butera A, et al.
Microorganisms. 2020 Dec 29;9(1):69. doi: 10.3390/microorganisms9010069.
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PMID: 33383903
Free PMC article.
Ryder MI, Shiboski C, Yao TJ, Moscicki AB.
Ryder MI, et al.
Periodontol 2000. 2020 Feb;82(1):65-77. doi: 10.1111/prd.12321.
Periodontol 2000. 2020.
PMID: 31850628
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These data represent 20 months of follow-up on 114 homo/bisexual men. Periodontal changes were analyzed in relation to HIV-1 serostatus, immune status, age and plaque. Gingival index (GI), plaque index (PI), and relative attachment levels recorded by the computerized Florida disk probe were performed every 4 months. A threshold of > or = 3.0 mm of relative attachment loss (RAL) was selected as a significant longitudinal change. RAL > or = 3 mm occurred 6.16 times (95% CI = 1.95, 19.40) more frequently among subjects with T4 counts < 200 compared to subjects with counts of 200 or more. Among older subjects (age > or = 35 years), the incidence (33%) of RAL > or = 3 mm was significantly higher (p = 0.004) in more immunosuppressed subjects (T4 < 200) compared to the incidence (5%) in less immunosuppressed subjects (T4 > or = 200); this association was not significant in younger subjects less than 35 years old (p = 0.55). In 78 subjects present at all follow-up visits, averaged GI increased and were significantly higher in the seropositive subjects compared to seronegative subjects, but, GI was not related to T4 cell counts within the seropositive group. Separate linear regression of GI by PI by HIV serostatus revealed a significantly higher slope in the seropositive group compared to the seronegative group (p = 0.04), suggesting greater sensitivity to plaque in the seropositive group.
Conclusion:
immunosuppression, especially in combination with older age, may be a risk factor for attachment loss, and HIV seropositivity, independent of T4 cell counts, may be a risk factor for gingival inflammation.
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