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Results of the randomized NOPHO ALL2008 asparaginase study (Peg-Asparaginase every 2 vs 6 week for patients aged 1-17 years) and investigation of asparaginase antibodies/silent inactivation are ...
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What is NOPHO? NOPHO - the Nordic Society of Paediatric Haematology and Oncology - is a Nordic association for paediatric oncology (childhood cancer). NOPHO has been an organisation for Nordic paediatric oncologists, both clinically and within research, since 1982.
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Kjeld Schmiegelow, MD, Rigshospitalet University Hospital, Copenhagen, Denmark, shares the key findings from the population-based Nordic/Baltic acute lymphoblastic leukemia (ALL) Nordic Society for Paediatric Haematology and Oncology (NOPHO) ALL2008 protocol. Overall, it was found that adult and pediatric patients have a distinct distribution of high-risk genetic factors and that there was a ...
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OS for childhood ALL is now >90%, but high-risk (HR) cases still need to improve. The NOPHO ALL2008 protocol restricted very intensive HR chemotherapy to patients with an inferior early minimal residual disease (MRD) response or HR genetics, and we here report the results for this subset.
Key findings from the NOPHO ALL2008 experience: advances in ALL diagnosis and treatment VJHemOnc - Video Journal of Hematology & HemOnc 15.4K subscribers Subscribed
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