Female Half Life

Female Half Life
If playback doesn't begin shortly, try restarting your device.
Videos you watch may be added to the TV's watch history and influence TV recommendations. To avoid this, cancel and sign in to YouTube on your computer.
An error occurred while retrieving sharing information. Please try again later.
0:00 / 1:00:50 • Watch full video Live

Please be respectful of copyright. Unauthorized use is prohibited.
This story appears in the January 2017 issue of National Geographic magazine.
Juan Sebastián Elcano completed the first known circumnavigation of the globe in September 1522. The Basque navigator led the tattered remains of Magellan's fleet back to Spain after the commander's death in 1521.
The mesmerizing sight brings back a long-cherished tradition—and an uptick in tourism
Biologists have a definition for teaching that very few animals actually meet, such as orcas and meerkats. Here are a few more from the head of the class.
The Persian Gulf nation’s plan will double its land mass—at a steep cost to its vibrant marine life.
Why animal teachers are so rare—and remarkable
Business and activism collide at a Texas horse auction
Where the buffalo roam, endangered prairies thrive
Everyday products may be harming the environment
Babies may practice crying months before they’re born
Dogs’ risk of dementia increases by half every year
5 surprising ways hemp helps the planet
Bahrain lacks land, so it's building more: lavish artificial islands
These ancient Dutch sunken roads hide stunning natural beauty
Rewilding the UK, one abandoned lot at a time
He has been fixing grandfather clocks for more than 40 years
These six islands existed in the imaginations of ancient explorers
This man was actually first to sail around the world
Color and magic fill Bali’s skies with the return of a beloved kite festival
How a derelict countryside bloomed into an ecoparadise
Why this ancient 'King of the World' was so proud of his library
Frank Drake, pioneer in the search for alien life, dies at 92
COVID-19 took a unique toll on undocumented immigrants
230-million-year-old fossil is Africa’s oldest known dinosaur
In space, flames become otherworldly
Lessons from nature – bringing waste back into the cycle
NASA’s most powerful rocket ever prepares for launch
See the ocean’s glow-in-the-dark world on a fluorescent night dive
Burning Man shows how a riotous festival can be accessible
Seaweed is a superfood you can forage. Here’s how.
See America’s parks with those who first called them home
These fabled ‘ghost’ islands exist only in atlases
Why are people so dang obsessed with Mars?
The era of greyhound racing in the U.S. is coming to an end
See how people have imagined life on Mars through history
See how NASA’s new Mars rover will explore the red planet
Why are people so dang obsessed with Mars?
The era of greyhound racing in the U.S. is coming to an end
See how people have imagined life on Mars through history
See how NASA’s new Mars rover will explore the red planet
Why are people so dang obsessed with Mars?
The era of greyhound racing in the U.S. is coming to an end
See how people have imagined life on Mars through history
See how NASA’s new Mars rover will explore the red planet
Follow us National Geographic Facebook National Geographic Twitter National Geographic Instagram
The typical eastern tiger swallowtail (Papilio glaucus) is either all dark or all yellow—but this bilateral gynandromorph has a yellow side that's male and a dark side that's female.
What’s a bilateral gynandromorph? A bird, crustacean—or butterfly—that’s a 50-50 split of male and female traits.
The difference in appearance between a species’ males and females is called sexual dimorphism. The term implies that there’s a bisecting line between sexes, a clear divide. But in the animal kingdom, a lot of creatures straddle it.
The natural world is replete with hermaphrodites, animals that may outwardly appear male or female but have the reproductive organs of both. Their less common cousins are gynandromorphs, animals that are a mosaic of male and female traits—say, the size and coloring of one with the genitalia of the other.
Rarer yet is the bilateral gynandromorph, an animal that’s half him and half her, split at the midline. The phenomenon has been documented in birds, crustaceans—and butterflies.
Evolutionary biologist Josh Jahner explains “what most scientists think happens” to form these outliers: Butterflies’ sex chromosomes are the reverse of humans’—males have two alike (ZZ), females two different (ZW). A female’s egg sometimes has two nuclei, a Z and a W. When they’re “double fertilized” by a male’s Z sperm, Jahner says, the resulting embryo is half each sex.
How rare are these specimens? In a 1980s study, a research team that raised nearly 30,000 butterflies found only five bilateral gynandromorphs among them. Colleagues at the University of Nevada, Reno have been “really excited,” Jahner says, to find four since 2011.
Jahner says gynandromorphs in his lab have tried but failed to lay eggs, likely because of an irregularity in their reproductive systems. So though their breed sports striking fusions of color, it’s a beauty they apparently can’t pass on.
HABITAT/RANGE: Woods, parks, and suburbs in the eastern half of the United States and parts of Canada
OTHER FACTS: The yellow side is male and the dark side is female on this bilateral gynandromorph eastern tiger swallowtail (shown about 1.5 times life-size). The term combines the Greek gyn, or female, and andro, or male.
Copyright © 1996-2015 National Geographic Society Copyright © 2015-2022 National Geographic Partners, LLC. All rights reserved

Ads keep us online. Without them, we wouldn't exist. We don't have
paywalls or sell mods - we never will. But every month we have large bills
and running ads is our only way to cover them. Please consider unblocking us. Thank you from GameBanana <3

14 LA clan skin Avaiable! :) It Release 1/20/02 ----------------------------------------------------------------------------------------------------------- LA-Armor LA-Boss LA-Camo LA-Devil LA-Female<---Now on List LA-Flyer LA-Gasmask LA-Leader LA-Male LA-Manager LA-Master LA-Ninja LA-Shark Include Special Editon skin is: LA-Sinister_Clown ----------------------------------------------------------------------------------------------------------- LA-Female is bad pissing girl! it have Crossbow on back plus extra arrow on her pocket! Handgun pocket! cool LA body suit,Eye Glow make up face! Hair on body suit! What a sexy lady! :) enjoy it ----------------------------------------------------------------------------------------------------------- Make sure you put in Half-Life folder in C:\SIERRA\Hale-Life\valve\models\Player "But Make your own folder file" Go to "Window Explorer" not Explorer internet! go to "C:\SIERRA\Hale-Life\valve\models\Player" then how make you own folder? "First you do click right on your mouse then go to "New" then in NEW click "Folder" then you see on screen say "New Folder"? click it again on your mouse then Type it a "model name" like LA- Whatever those name! LOL! anyway you have model name already then open model zip file then put All .bmp, .mdl,and .txt file in Foler :) enjoy it dude :) Bryan:MDP ----------------------------------------------------------------------------------------------------------- brought to you by : http://hlweb.sunlitsurf.com/ , www.severian.org, www.tgpclan.com

Clipboard, Search History, and several other advanced features are temporarily unavailable.

Dashboard
Publications
Account settings
Log out

Advanced

Clipboard

Format

Abstract

PubMed

PMID

Format:

Summary (text)
PubMed
PMID
Abstract (text)
CSV

Subject:

1 selected item: 31010782 - PubMed

Format:

Summary
Summary (text)
Abstract
Abstract (text)

Create a new collection

Add to an existing collection

Name must be less than 100 characters

Unable to load your collection due to an error
Please try again

Unable to load your delegates due to an error
Please try again

Would you like email updates of new search results?

Saved Search Alert Radio Buttons

Yes

No

Frequency:

Monthly
Weekly
Daily

Which day?

The first Sunday
The first Monday
The first Tuesday
The first Wednesday
The first Thursday
The first Friday
The first Saturday
The first day
The first weekday

Which day?

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday

Report format:

Summary
Summary (text)
Abstract
Abstract (text)
PubMed

Send at most:

1 item
5 items
10 items
20 items
50 items
100 items
200 items

Send even when there aren't any new results

Number of items displayed:

5
10
15
20
50
100

Page navigation

Title & authors

Abstract

Similar articles

Cited by

MeSH terms

Substances

Related information

LinkOut - more resources

Affiliations

1 Department of Obstetrics and Gynecology. Mayo Clinic College of Medicine, Rochester, MN, USA.

2 Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

3 Department of Pharmacology, Mayo Clinic College of Medicine, Rochester, MN, USA.

4 Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Department of Pharmacology, Mayo Clinic College of Medicine, Rochester, MN, USA.

5 Women's Health, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.

6 Department of Obstetrics and Gynecology. Mayo Clinic College of Medicine, Rochester, MN, USA. Electronic address: Green.isabel@mayo.edu.

Alyssa M Larish et al.

J Sex Med .

2019 Jun .

Format

Abstract

PubMed

PMID

Affiliations

1 Department of Obstetrics and Gynecology. Mayo Clinic College of Medicine, Rochester, MN, USA.

2 Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

3 Department of Pharmacology, Mayo Clinic College of Medicine, Rochester, MN, USA.

4 Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Department of Pharmacology, Mayo Clinic College of Medicine, Rochester, MN, USA.

5 Women's Health, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.

6 Department of Obstetrics and Gynecology. Mayo Clinic College of Medicine, Rochester, MN, USA. Electronic address: Green.isabel@mayo.edu.

Rogalski MJ, Kellogg-Spadt S, Hoffmann AR, Fariello JY, Whitmore KE.
Rogalski MJ, et al.
Int Urogynecol J. 2010 Jul;21(7):895-9. doi: 10.1007/s00192-009-1075-7. Epub 2010 Jan 12.
Int Urogynecol J. 2010.

PMID: 20066399

Carrico DJ, Peters KM.
Carrico DJ, et al.
Urol Nurs. 2011 Sep-Oct;31(5):279-84, 299.
Urol Nurs. 2011.

PMID: 22073898

Clinical Trial.

Crisp CC, Vaccaro CM, Estanol MV, Oakley SH, Kleeman SD, Fellner AN, Pauls RN.
Crisp CC, et al.
Int Urogynecol J. 2013 Nov;24(11):1915-23. doi: 10.1007/s00192-013-2108-9. Epub 2013 May 17.
Int Urogynecol J. 2013.

PMID: 23681047

Clinical Trial.

Padoa A, McLean L, Morin M, Vandyken C.
Padoa A, et al.
Sex Med Rev. 2021 Jan;9(1):76-92. doi: 10.1016/j.sxmr.2020.04.002. Epub 2020 Jul 4.
Sex Med Rev. 2021.

PMID: 32631813

Review.

Faubion SS, Shuster LT, Bharucha AE.
Faubion SS, et al.
Mayo Clin Proc. 2012 Feb;87(2):187-93. doi: 10.1016/j.mayocp.2011.09.004.
Mayo Clin Proc. 2012.

PMID: 22305030
Free PMC article.

Review.

Shrikhande A, Ullger C, Seko K, Patil S, Natarajan J, Tailor Y, Thompson-Chudy C.
Shrikhande A, et al.
Pain Rep. 2021 Aug 30;6(3):e949. doi: 10.1097/PR9.0000000000000949. eCollection 2021 Sep-Oct.
Pain Rep. 2021.

PMID: 34476302
Free PMC article.

Review.

Cornett EM, Amarasinghe SN, Angelette A, Abubakar T, Kaye AM, Kaye AD, Neuchat EE, Urits I, Viswanath O.
Cornett EM, et al.
Neurol Int. 2021 Feb 18;13(1):64-78. doi: 10.3390/neurolint13010007.
Neurol Int. 2021.

PMID: 33670456
Free PMC article.

Review.

Gracely A, Cameron AP.
Gracely A, et al.
Drugs Aging. 2021 Jan;38(1):1-16. doi: 10.1007/s40266-020-00810-w. Epub 2020 Oct 23.
Drugs Aging. 2021.

PMID: 33094445

Review.

Format:

AMA

APA

MLA

NLM

Send To

Clipboard

Email
Save

My Bibliography
Collections

Citation Manager

[x]

NLM

NIH

HHS

USA.gov

An official website of the United States government

The .gov means it’s official.

Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.

The site is secure.

The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.

Background:

Vaginal diazepam is frequently used to treat pelvic floor tension myalgia and pelvic pain despite limited knowledge of systemic absorption.

Aim:

To determine the pharmacokinetic and adverse event profile of diazepam vaginal suppositories.

Methods:

We used a prospective pharmacokinetic design with repeated assessments of diazepam levels. Eight healthy volunteers were administered a 10-mg compounded vaginal diazepam suppository in the outpatient gynecologic clinic. Serum samples were collected at 0, 45, 90, 120, and 180 minutes; 8, 24, and 72 hours; and 1 week following administration of a 10-mg vaginal suppository. The occurrence of adverse events was assessed using the alternate step and tandem walk tests, the Brief Confusion Assessment Method, and numerical ratings. Plasma concentrations of diazepam and active long-acting metabolites were measured. Pharmacokinetic parameters were calculated by standard noncompartmental methods.

Results:

The mean peak diazepam concentration (C max ) of 31.0 ng/mL was detected at a mean time (T max ) of 3.1 hours after suppository placement. The bioavailability was found to be 70.5%, and the mean terminal elimination half-life was 82 hours. The plasma levels of temazepam and nordiazepam peaked at 0.8 ng/mL at 29 hours and 6.4 ng/mL at 132 hours, respectively. Fatigue was reported by 3 of 8 participants.

Clinical implications:

Serum plasma concentrations of vaginally administered diazepam are low; however the half-life is prolonged.

Strengths & limitations:

Strengths include use of inclusion and exclusion criteria aimed at mitigating clinical factors that could adversely impact diazepam absorption and metabolism, and the use of an ultrasensitive LC-MS/MS assay. Limitations included the lack of addressing the efficacy of vaginal diazepam in lieu of performing a pure pharmacokinetic study with healthy participants.

Conclusion:

Vaginal administration of diazepam results in lower peak serum plasma concentration, longer time to peak concentration, and lower bioavailability than standard oral use. Providers should be aware that with diazepam's
Blonde Babe Teen
Nude Casting Couch-X
Fat Mature Lick

Female Half Life

Report Page