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Not a MyNAP member yet? Register for a free account to start saving and receiving special member only perks. The Health Effects of Cannabis and Cannabinoids. This activity was supported by Grant No. Woodruff Foundation; Truth Initiative; U. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. The health effects of cannabis and cannabinoids: The current state of evidence and recommendations for research. The National Academy of Sciences was established in by an Act of Congress, signed by President Lincoln, as a private, nongovernmental institution to advise the nation on issues related to science and technology. Members are elected by their peers for outstanding contributions to research. Marcia McNutt is president. The National Academy of Engineering was established in under the charter of the National Academy of Sciences to bring the practices of engineering to advising the nation. Members are elected by their peers for extraordinary contributions to engineering. Mote, Jr. The National Academy of Medicine formerly the Institute of Medicine was established in under the charter of the National Academy of Sciences to advise the nation on medical and health issues. Members are elected by their peers for distinguished contributions to medicine and health. Victor J. Dzau is president. The three Academies work together as the National Academies of Sciences, Engineering, and Medicine to provide independent, objective analysis and advice to the nation and conduct other activities to solve complex problems and inform public policy decisions. The National Academies also encourage education and research, recognize outstanding contributions to knowledge, and increase public understanding in matters of science, engineering, and medicine. Reports document the evidence-based consensus of an authoring committee of experts. Reports typically include findings, conclusions, and recommendations based on information gathered by the committee and committee deliberations. Reports are peer reviewed and are approved by the National Academies of Sciences, Engineering, and Medicine. Proceedings chronicle the presentations and discussions at a workshop, symposium, or other convening event. The statements and opinions contained in proceedings are those of the participants and have not been endorsed by other participants, the planning committee, or the National Academies of Sciences, Engineering, and Medicine. For information about other products and activities of the National Academies, please visit nationalacademies. ZIVA D. ADRE J. This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report:. Donald P. Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations nor did they see the final draft of the report before its release. The review of this report was overseen by Eric B. Berkowitz , Columbia University Medical Center. They were responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution. This report reflects contributions from a number of individuals and groups. The committee takes this opportunity to recognize those who so generously gave their time and expertise to inform its deliberations. To begin, the committee would like to thank the sponsors of this study for their guidance and support. The committee greatly benefited from the opportunity for discussion with individuals who attended and presented at their open session meetings see Appendix D. The committee is thankful for the many contributions of these individuals. The committee could not have done its work without the support and guidance provided by the National Academies project staff: Leigh Miles Jackson, study director; Jennifer Cohen, program officer; Kelsey Geiser, research associate; R. Brian Woodbury, research associate; Sara Tharakan, research associate; Matthew Masiello, research assistant; and Marjorie Pichon, senior program assistant. The committee is also grateful to Hope R. Hare and Doris Romero for their administrative and financial. Many other staff within the National Academies provided support to this project in various ways. Finally, Robert Pool is to be credited for his superb editorial assistance in preparing this report. Study Context and Approach. Report Recommendations. Study Charge. Report Organization. History of Cannabis. The Cannabis Plant. Cannabis-Derived Products. Clinical Features of Cannabis Intoxication. Cannabinoid-Based Medications. Synthetic Cannabinoids as Recreational Drugs. Cannabis Contaminants and Adulterants. Prevalence of Cannabis Use in the United States — Cannabis Regulation in the United States. Policy Landscape. Executive Branch Policies. Congressional Branch Policies. Public Opinion. Policy and Research. Chronic Pain. Chemotherapy-Induced Nausea and Vomiting. Anorexia and Weight Loss. Irritable Bowel Syndrome. Tourette Syndrome. Amyotrophic Lateral Sclerosis. Sleep Disorders. Posttraumatic Stress Disorder. Schizophrenia and Other Psychoses. Research Gaps. Acute Myocardial Infarction. Pulmonary Function. Chronic Obstructive Pulmonary Disease. Respiratory Symptoms, Including Chronic Bronchitis. Immune Competence. Susceptibility to and Progression of Infectious Disease. Research Gap. All-Cause Mortality. Occupational Injury. Motor Vehicle Crashes. Overdose Injuries and Death. Pregnancy Complications for the Mother. Fetal Growth and Development. Neonatal Conditions. Later Outcomes. Academic Achievement. Employment and Income. Social Relationships and Other Social Roles. Bipolar Disorder. Problem Cannabis Use. Abuse of Other Substances. Regulatory and Supply Barriers. Methodological Challenges. Address Research Gaps. Improve Research Quality. Improve Surveillance Capacity. Address Research Barriers. A Glossary. B Study Approach. C Systematic Reviews. D Public Session Agendas. Eight of these states and the District of Columbia have also legalized cannabis for recreational use. In addition to the growing availability of legalized cannabis, there has also been a rapid expansion in the types of available cannabis products, including edibles, oils, and a variety of inhaled substances. The growing acceptance, accessibility, and use of cannabis raise important public health concerns, and there is a clear need to establish what is known and what needs to be known about the health effects of cannabis use. The committee was tasked with conducting a comprehensive review of the current evidence regarding the health effects of using cannabis and cannabis-derived products. In the current report, the committee presents a rigorous and thoughtful summary of the landscape of cannabis and health and puts forth recommendations to help advance the research field and better inform public health decisions. I wish to express my deepest gratitude to my fellow committee members who worked so hard and with good grace to accomplish this task. As with other National Academies of Sciences, Engineering, and Medicine reports, the work of the committee would have been. Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agenda—outlining gaps in current knowledge and opportunities for providing additional insight into these issues—that summarizes and prioritizes pressing research needs. Based on feedback from you, our users, we've made some improvements that make it easier than ever to read thousands of publications on our website. Jump up to the previous page or down to the next one. Also, you can type in a page number and press Enter to go directly to that page in the book. Switch between the Original Pages , where you can read the report as it appeared in print, and Text Pages for the web version, where you can highlight and search the text. To search the entire text of this book, type in your search term here and press Enter. Ready to take your reading offline? Click here to buy this book in print or download it as a free PDF, if available. Do you enjoy reading reports from the Academies online for free? Sign up for email notifications and we'll let you know about new publications in your areas of interest when they're released. Get This Book. Visit NAP. Looking for other ways to read this? No thanks. Page i Share Cite. Suggested Citation: 'Front Matter. Page ii Share Cite. Copyright by the National Academy of Sciences. All rights reserved. Page iii Share Cite. Page iv Share Cite. Page v Share Cite. Page vi Share Cite. Page vii Share Cite. Reviewers This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. Furstenberg, Jr. Page viii Share Cite. Ware , McGill University. Page ix Share Cite. Acknowledgments This report reflects contributions from a number of individuals and groups. Page x Share Cite. Page xi Share Cite. Page xii Share Cite. Page xiii Share Cite. Page xiv Share Cite. Page xv Share Cite. Page xvi Share Cite. Page xvii Share Cite. Page xviii Share Cite. Marie C. Login or Register to save! Stay Connected!
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More information is needed on the positive and negative health effects of marijuana, according to a new report released January 12, by the National Academies of Sciences, Engineering and Medicine. Marijuana is now approved for medicinal or recreational use in 28 states plus the District of Columbia, but federal government restrictions have made it difficult to conduct rigorous research on the drug. Chan School of Public Health, examined more than 10, marijuana studies. They found that the much of the current body of evidence does not provide any clear guidelines regarding populations that may benefit or be harmed by marijuana, or on the effects of different dosages and delivery mechanisms. The committee did report some conclusive findings. On the plus side, marijuana has been shown to ease chronic pain and chemotherapy-induced nausea in cancer patients. But other substantial evidence suggests that marijuana can negatively affect fetal development among women who use marijuana during pregnancy. It is also linked with greater risk of chronic bronchitis and other worsened respiratory symptoms. The overall lack of evidence-based information poses a public health risk, according to the committee. Skip to content News. News Menu. Search for:.
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Lack of conclusive evidence on marijuana’s health effects poses public health risk
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