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Information provided by (Responsible Party):
Lisa Buckloh, PhD, Nemours Children's Clinic
This is a randomized, controlled pilot trial of Behavioral Family Systems Therapy for Teens with Type 2 Diabetes (BFST-DM2), an individual psychological intervention tailored to meet the needs of teens with type 2 diabetes. It is hypothesized that this behavioral family intervention will be feasible to implement with teens with type 2 diabetes and will have positive effects on treatment adherence, health outcomes like weight status and metabolic control, and psychological outcomes.
The incidence of type 2 diabetes mellitus (DM2) in youth is increasing dramatically with the rise in obesity in the U.S. and worldwide. DM2 in youth, as with adults, is clearly linked to modifiable risk factors such as obesity, sedentary lifestyle, and poor diet. Youth with DM2 are at increased risk for medical complications such as cardiovascular disease, retinopathy, and neuropathy, as well as psychological problems such as depression, anxiety, poor self-esteem, eating disorders, and poor coping and problem solving. Although there are studies demonstrating that family-based lifestyle and psychological interventions are successful in reducing obesity in youth and in improving metabolic control and adherence in youth with type 1 diabetes mellitus (DM1), very little has been published on potential lifestyle or psychological treatments for youth with DM2. Studies have shown that Behavioral Family Systems Therapy (BFST) has been effective in improving metabolic control, adherence, family communication, and problem solving in youth with DM1. This intervention could be effective in treating youth with DM2, as many of the skills necessary for good metabolic control, health outcomes, treatment adherence, and psychological adjustment are similar in both populations. This application proposes a randomized, controlled pilot trial of BFST-DM2, an individual psychological intervention tailored to meet the needs of teens with DM2. BFST will be adapted to make this intervention more feasible and relevant with minority and low-income populations and also to focus on weight management, exercise, and nutrition. The BFST-DM2 intervention includes 12 (90-minute) sessions over 6 months. Areas targeted for improvement will include metabolic control, weight/body mass index, treatment adherence, family lifestyle choices (activity, diet), family communication, and problem solving. One of the main aims of this pilot study is to gather exploratory information on the effectiveness of the BFST-DM2 intervention on measures of health outcomes, medical adherence, lifestyle changes, and family problem-solving and communication skills. In addition, it is an aim to estimate treatment effect size to determine the sample size needed to power a larger multi-site trial of the BFST-DM2 intervention. Other aims include determining factors associated with feasibility (recruitment, retention, participation, generalizability) as well as to modify the intervention to be culturally sensitive and to be more relevant to the individual needs of the DM2 adolescent population. The BFST-DM2 intervention will be compared with standard medical therapy on measures of health outcomes (metabolic control, body mass index, weight, waist circumference, body fat) physical activity (accelerometer), nutritional intake, treatment adherence, psychological adjustment (self-esteem, quality of life), family communication, and problem solving. The researchers will analyze predictors of treatment outcome and the treatment effects at the immediate post-treatment interval (6 months from baseline). Health outcomes and medical adherence data also will be collected 12 months from baseline to determine maintenance of treatment effects over time.

MedlinePlus Genetics related topics:
TypeΒ 2Β diabetes

Psychological intervention: Families randomized to the intervention group will receive 12 sessions of Behavioral Family Systems Therapy for Teens with type 2 diabetes (BFST-DM2) over 6 months.
BFST for Teens with Type 2 Diabetes: 12 (90 minute sessions) over 6 months of Behavioral Family Systems Therapy (BFST), delivered by a Licensed clinical social worker. BFST consists of 4 components: problem-solving, communication skills training, cognitive restructuring, and functional and structural family therapy.
Other Name: BFST - Behavioral Family Systems Therapy
The participants assigned to the control group will receive their standard medical care for diabetes.
Body Mass Index (adjusted for height, gender, and age) - height and weight in kg and meters (kg/m^2) - change in BMI across time points is being studied - change in weight from baseline to 6 months and change in weight from baseline to 12 months
Metabolic control is measured using HbA1c values
Treatment Adherence is measured using the Diabetes Self Management Survey for Teens with Type 2 Diabetes.
Family problem-solving is measured using the Revised Diabetes Family Conflict Scale
Physical activity is measured by an accelerometer
Body fat percent change - measured by a hand-held body fat impedance device
Nutrition/food intake as measured by the Nutrition Data Systems for Research interview
Family communication skills are measured by the Family Communication (Interaction Behavior Code)
Teen Self-Perception/Self-esteem is measured by the Harter Self-Perception Profile
Teen Quality of Life is measured by The Pediatric Quality of Life Inventory (PedsQL)
Keywords provided by Lisa Buckloh, PhD, Nemours Children's Clinic:


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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03159221



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ClinicalTrials.gov Identifier: NCT03159221

Diabetes Mellitus, Type 2
Childhood Obesity


Behavioral: BFST for Teens with Type 2 Diabetes


Interventional
Β (Clinical Trial)



Behavioral Family Systems Therapy for Teens With Type 2 Diabetes: A Pilot
Jacksonville, Florida, United States, 32207
Lisa Buckloh, PhD, Clinical Research Psychologist, Nemours Children's Clinic

NCT03159221Β Β 

History of Changes


May 18, 2017
Β Β 
Key Record Dates

Individual Participant Data (IPD) Sharing Statement:

type 2 diabetes in adolescents
obesity in adolescents
behavioral family systems therapy


Diabetes Mellitus
Diabetes Mellitus, Type 2
Pediatric Obesity
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases


Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight



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Home Β» Publications Β» Family Matters Β» Issue 88 Β» What works with adolescents?
Family connections and involvement in interventions for adolescents problem behaviours

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https://clinicaltrials.gov/ct2/show/NCT03159221
https://aifs.gov.au/publications/family-matters/issue-88/what-works-adolescents
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