Expiration Dating For Multiple Dose Vials Of Injectables

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Questions about Multi-dose vials | Injection Safety | CDC
Multi-dose Vials - Expectations for Managing Multi-dose . . .
PDF Policy for the use of multiple dose vials of injectable . . .
Questions about Single-dose/Single-use Vials | Injection . . .
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If a multi- dose has been opened or accessed (e .g ., needle-punctured) the vial should be dated and discarded within 28 days unless the manufacturer specifies a different (shorter or longer) date for that opened vial . If a multi- dose vial has not been opened or accessed (e .g ., needle-punctured), it should be discarded according to the manufacturer's expiration date .
Expiration Dating : Multi- dose vials are to be discarded 28 days after first use unless the manufacturer specifies otherwise (shorter or longer) . Once the container has been punctured, an updated expiration date must be determined and applied to the container .
5 .4 . Multi- dose vials may be used to prepare more than one dose . The storage time will be limited once the first dose is withdrawn from the vial . Multi- dose vials once opened must be kept refrigerated during the in-use storage time unless stated otherwise in the product information and labelled with the time and date opened .
A single- dose or single-use vial is a vial of liquid medication intended for parenteral administration (injection or infusion) that is meant for use in a single patient for a single case, procedure, injection . Single- dose or single-use vials are labeled as such by the manufacturer and typically lack an antimicrobial preservative .
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Expiration Dating For Multiple Dose Vials Of Injectables