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This would allow psychiatrists to use these drugs in combination with psychotherapy for the treatment of conditions such as depression and post-traumatic stress disorder PTSD. The TGA cited limited evidence of therapeutic benefit, safety concerns, potential for abuse, and lack of suitably trained psychiatrists. But the final ruling, which was expected on April 22, has now been delayed while the TGA on the ''therapeutic value, risks, and benefits to public health'' of the change. The number of clinical trials has increased steadily in the past decade, with more than 70 studies completed since For example, last month, of 59 patients with major depression showed just two sessions of psilocybin-assisted therapy was as effective as a six-week course of the antidepressant escitalopram. The proportion of patients who no longer qualified for a major depression diagnosis after treatment was twice as high in the psilocybin group. These latest studies add to a growing number of trials from around the world showing the therapeutic benefit of psilocybin or MDMA in depression, PTSD, , , , and. Scientists are now investigating the use of psilocybin in other conditions for the first time, such as , , and and. Unlike many Schedule 8 medicines, psilocybin- or MDMA-assisted psychotherapy treatments are not taken regularly. The substance is usually used just with trained specialists as part of a psychotherapy program. Despite the safety concerns cited by the TGA, there haven''t been any serious adverse reported events due to or from dozens of clinical trials. Less serious effects can include temporary anxiety, paranoia, fear, nausea, post-treatment headaches, or mild increases in blood pressure and heart rate. However, one of the most comprehensive of the harms of commonly used illegal drugs found even illicit forms of psilocybin and MDMA are among the least harmful. In fact, ''mushrooms'' containing psilocybin had the lowest overall harm score, while illicit forms of clinically-used like cocaine, cannabis and ketamine were all more harmful than psilocybin or MDMA. We don''t know what dose of psilocybin would be lethal to humans, but it's estimated to be about than the therapeutic dose. No overdose deaths due to have ever been reported. Use of illicitly manufactured MDMA — which often contains other drugs or impurities — has occasionally caused deaths. But illicit use of MDMA of unknown dose and purity is much more dangerous than administration of pharmaceutical MDMA under medical supervision in a clinical environment. In recent years, respected academic and medical institutions around the world have launched dedicated centres for psychedelic and MDMA research, including and. The Australian government recently announced for research into the medical potential of psychedelics and MDMA. It's hard to reconcile the TGA's interim decision to retain Schedule 9 for substances with demonstrated benefit in several mental health conditions and fewer safety concerns than many existing Schedule 8 medicines. The US medicines regulator recently granted MDMA and psilocybin '' '' designation; a special status for highly promising drugs that speeds up their path to the clinic. The down-scheduling of psilocybin and MDMA could have enormous medical benefit for Australian patients, especially when Australia spent on mental health between We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above. Daily English Daily Arabic All. App Store. Share on Facebook Tweet on Twitter. Author: S. Here's why we believe that would be a good idea. If MDMA and psilocybin are reclassified, they would be administered in a supervised environment. Around 60 trials are underway in Europe and the United States involving or. Read more: The results of completed studies are very promising. Studies are showing MDMA and psilocybin can be effective in treating a variety of mental health problems. Of course, these trials use pharmaceutical-grade drugs administered by a doctor. A growing field In recent years, respected academic and medical institutions around the world have launched dedicated centres for psychedelic and MDMA research, including and. Read more: It's hard to reconcile the TGA's interim decision to retain Schedule 9 for substances with demonstrated benefit in several mental health conditions and fewer safety concerns than many existing Schedule 8 medicines. Tags Australia UnitedStates. Comments No comment. Most popular stories. Deepak Parekh says life insurers should be allowed to evolve further. 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