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Puzzled but flattered by the ATA. Now, hypothetically, someone using Methylphenidate recreationally might want to potentiate the effects using various methods. As other people suggested changing the route of admission will enhance the effects for the same dose - basically anything hitting your bloodstream fast, especially if it bypasses your liver, will hit our fictional pre. As other people suggested changing the route of admission will enhance the effects for the same dose - basically anything hitting your bloodstream fast, especially if it bypasses your liver, will hit our fictional prescription drug abuser much harder. Snorting has been mentionned. So to speak. Smoking is another option. A more elegant solution would be to convert the substance to a freebase, which would have a much lower evaporation temperature. Methylphenidate is not active sublingually, but there is another route that gives you very quick access to the bloodstream and bypasses the liver. Yup, I referring to sticking it up your bottom. That would work for sure. Beyond ROA, you can endeavour to boost the levels of the monoamine neurotransmitters that Methylphenidate acts upon. The gentle way would be to load up on the amino acids your body used to make those neurotransmitters, in the hope more of them will be made. Failing this L-tyrosine would get your body to produce more L-dopa, and hopefully ultimately make more of the enjoyable neurotransmitters available. Or you could try combining it with a Monoamine Oxidase Inhibitor - natural or pharmaceutical. Such a combination would be rather dangerous, and potentially lethal. A final way of potentiating the effects is to act upon the normal metabolisation routes. As many other drugs, Methylphenidate is metabolised by Cytochrome P45 - grapefruit juice is known to be very efficient at inhibiting this particular enzyme. That might be the simplest option. Have a glass or two of grapefruit juice a couple of hours before normal oral administration. This means more of the drug will hit your bloodstream to start with less is lost when going from your GI tract to your blood via the liver and that it will stay in your bloodstream for longer. Some are dangerous, some merely idiotic, all are hypothetical. Using Ritalin as a drug of abuse is not very smart. So yeah. But hey, who am I to judge? Either by taking it on an empty stomach or mixing it with sodium bicarbonate or an antiacid, or both. Taking it with a MAOI would increase the effectiveness exponentially as well but it would bring an increased risk of side effects. Mixing it with alcohol would increase your blood concentration of it too, but this is very dangerous. If you need to increase the effectiveness then taking it with a low dose of turmeric a reversible MAOI that fights inflammation and piperine could increase your dopamine as well as serotonin somethi. Taking a daily omega complex supplement may be helpful as well. You may also want to try taking some protein once it starts kicking in because of the benefits of that bunch of amminoacids on energy. Zinc can also help in increasing your energy. Other things you could do are adding citicoline on top of this mg is what I take , magnesium to relax the muscles because methylphenidate increases noradrenaline which tenses you and speeds up your heart rate. A bit of dark chocolate when starting the day may help as well just make sure you avoid tea or coffee at all costs. CoQ and B complex may give you an energy boost as well. If you add Reishi mushroom on top of that it may be too much so try to avoid it. I would not recommend supplementing with L-Tyrosine as it may give you a racing heart and too much anxious energy. If you feel too jittery maybe some garlic, blueberry, chamomille, and meditation would help calm you a bit. And finally, if you decide to follow any of these advices then you must have asked your doctor first. Take a week break from stimulants. Drink a whey protein shake shortly after taking the stimulant. Works wonders. Get regular exercise -- 3o minutes of cardio at least 3 times a week. Also makes a huge difference when it comes to stimulant tolerance. Methylphenidate is basically a simplified synthetic version of cocaine. Methylphenidate crushed between two spoons then chopped and snorted gives a very similar high to cocaine. This is why methylphenidate often comes in pills that are designed not to be crushable. Using it this way will have no benefit for ADHD. It will just give you a short term high followed by the same kind of problems as a cocaine addiction. Take 10mg of Olanzapine for 3 to 5 days. The day you stop taking olanzapine, take your dosage of methylphenidate. You will have a high similar to speed that will last around 7 hours. Sign In. Quora uses cookies to improve your experience. Read More. Methylphenidate Ritalin. Attention Deficit Hyperactivity Disorder. How-to Question. How do I potentiate effects of methylphenidate? Ad by Grammarly. Writing something important? Join over 20 million Grammarly users and see what better, clearer writing can do for you. Learn More. Quora User. As other people suggested changing the route of admission will enhance the effects for the same dose - basically anything hitting your bloodstream fast, especially if it bypasses your liver, will hit our fictional pre Continue Reading. Related Questions. More Answers Below. How does a person with ADHD without medication because of the downsides of stimulant meds learn to focus on one endeavor long enough to live up to their potential? Or does it have a cummulative toxic effect s? What does it feel like to take methylphenidate Ritalin? Why is methylphenidate Ritalin a stimulant while bupropion is not a stimulant? Answered July 14, If you need to increase the effectiveness then taking it with a low dose of turmeric a reversible MAOI that fights inflammation and piperine could increase your dopamine as well as serotonin somethi Continue Reading. Sponsored by YouHodler. Earn 4. Answered April 16, Katie Powell. Is Ritalin worth taking? Why or why not? What are the pros and cons of using pseudoephedrine as a substitute for methylphenidate in adult ADD? Answered June 10, Sponsored by Power Life. Celebrity trainer: I feel better at 60 thanks to these 4 foods. Tony Horton reveals the revolutionary at home trick that saved his life. Watch More. Which is the best extended release formulation of methylphenidate? If so many drugs primarily affect dopamine, why do they all have different effects? Can Ritalin stop working? What are the benefits of using the Ritalin drug? If you take Concerta in the early morning, can you rely on its effect to help with attention deficit if you needed your undivided attention late at night? Ritalin is a new med for me. What are the chances that my Dr. If ADHD and anxiety both increase dopamine level, what happens when someone with both conditions takes a stimulant? How long does methylphenidate stay in your system, and how can you get rid of it? I accidentally took a double dose of Ritalin. What should I expect during the next few hours?

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