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KidsHealth /
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Klinefelter Syndrome

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Turner Syndrome

Triple X Syndrome

XYY Syndrome

Male Reproductive System

Sexual Development

Genetics

Klinefelter Syndrome

Growth Problems

Delayed Puberty

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Klinefelter syndrome is a fairly common genetic condition found in males only.
Many boys with Klinefelter syndrome — also known as XXY syndrome — have no signs or symptoms, and some don't even know they have it until later in life.
The XXY condition that causes Klinefelter syndrome can't be changed, but medical treatment and working with therapists can help a boy's development and lessen the condition's effects. Even without treatment, most boys with Klinefelter syndrome grow up to live productive, healthy lives.
Boys who have Klinefelter syndrome are born with it. It's also called XXY because they have an extra X chromosome
in most or all their cells.
Usually, a person has 46 chromosomes in each cell, divided into 23 pairs, which includes two sex chromosomes. Half the chromosomes are inherited from the father and the other half from the mother. The chromosomes contain genes, which determine an individual's characteristics, such as eye color and height. Boys typically have one X chromosome and one Y chromosome, or XY, but boys with XXY syndrome have an extra X chromosome, or XXY.
Klinefelter syndrome is not caused by anything the parents did or did not do. The disorder is a random error in cell division that happens when a parent's reproductive cells are being formed.
If one of these defective cells contributes to a successful pregnancy, the baby will have the XXY condition in some or all his cells. Some boys will even have more than two X chromosomes (XXXY or XXXXY, for example), which increases the risk of severe symptoms and other health concerns.
When a boy is born with the XXY condition in only some cells, it's called mosaic Klinefelter syndrome . Often, boys and men with this condition have milder signs and symptoms than others with the XXY condition.
Not all boys with Klinefelter syndrome will have noticeable symptoms. Other boys can have symptoms that are physically apparent or problems with speech, learning, and development.
Babies with Klinefelter syndrome typically have weak muscles, reduced strength, and quiet personalities. They also can take longer to do things like sit up, crawl, walk, and speak.
Compared with other kids their age, boys with Klinefelter syndrome might have some or all of these symptoms:
Klinefelter syndrome typically causes a boy's testicles to grow at a slower rate than those of other boys. It also prevents the testicles from producing normal amounts of sperm and the hormone testosterone .
Testosterone affects the way a boy develops both physically and sexually. Low hormone levels and problems with sperm production make it difficult or sometimes impossible for a boy with Klinefelter syndrome to father a child later in life.
Many boys with Klinefelter syndrome show symptoms related to their development of social and language skills. They may have trouble paying attention. A lot of boys learn to talk late or have trouble using words to express their emotions. They also can have trouble with things like learning to spell, read, and write.
Socially, they tend to have quiet personalities. They rarely cause trouble and are often more helpful and thoughtful than other boys. They're often shy and sensitive, and many are less self-confident and less active than other boys their age.
Most boys aren't likely to have major health problems, but the condition can bring some other challenges later in life. Klinefelter syndrome puts males at greater risk of breast cancer, some other cancers , and some other diseases like type 2 diabetes, varicose veins and problems with blood vessels, problems with sexual function, and osteoporosis (weak bones) later in life.
Most boys with Klinefelter syndrome can have sex when they become men, usually with the help of testosterone treatment. But problems with their testicles prevent them from making enough normal sperm to father children. Most men with the condition are infertile and can't father a child the usual way. Options for becoming natural parents are limited, but fertility researchers are working on new treatments. By the time someone with Klinefelter syndrome is ready to become a dad, there may be new options available related to saving sperm from the testicles.
Since Klinefelter syndrome can be hard to notice, many parents don't know their son has it until he grows up or shows delays in puberty. Sometimes, parents who are worried about their son's development consult a doctor, and the diagnosis reveals Klinefelter syndrome. This can help, because the earlier a boy is diagnosed with Klinefelter syndrome, the more effective the treatments usually are.
To diagnose Klinefelter syndrome, doctors usually begin by asking about any learning or behavior issues and examining the boy's testicles and body proportions. They'll check a blood sample for the extra X chromosome. Before birth, the condition may be found through chromosomal analysis or noninvasive prenatal testing (NIPT). NIPT is done on the fluid surrounding the fetus, tissue from the placenta, or the blood from the mother. After birth, doctors can make a diagnosis with a chromosome karyotype test
or microarray test
from the baby. Doctors also can do hormone testing, usually by taking a blood sample to check for unusual hormone levels.
There's no way to change the XXY condition if a boy is born with it, but treatments can help relieve some symptoms. As with many conditions, beginning treatment early can make it much more effective.
Testosterone replacement therapy (TRT) works by increasing a boy's testosterone levels into the normal range. Additional testosterone can help a boy with Klinefelter syndrome develop bigger muscles and a deeper voice, as well as promote growth of the penis and facial and body hair. It can also help improve bone density and reduce the growth of a boy's breasts. Testosterone therapy cannot increase the size of a boy's testicles or prevent or reverse infertility, though.
Educational support services can help boys and teens with Klinefelter syndrome keep pace in school. Many benefit from extra help with schoolwork. If your son has Klinefelter syndrome, let his teachers and school nurse know and see what kind of support is available. He may be eligible for an individualized education plan (IEP) or 504 education plan , which both can provide help for kids with special needs. Speech therapy and physical therapy can help boys with Klinefelter syndrome learn to speak, read, and write better, or improve muscle strength and coordination. Other forms of therapy include behavioral, mental health, and occupational therapy . These can help improve low self-confidence, shyness, and delayed social development.
Because boys with Klinefelter syndrome can have problems with schoolwork and sports, they may feel like they don't fit in with other kids their age. They're more likely to have low self-esteem, which can make things harder socially and academically. But by the time they're men, most will have normal social relationships with friends, family members, and others.
If your son struggles in school or has trouble making friends, talk to your doctor, school principal, or school counselor. Counselors and therapists can give boys practical skills to help them feel more confident in social settings. And many schools provide educational services that can help your son succeed.
Despite physical differences and other problems, with the right medical care, early intervention, and ongoing support, a boy with Klinefelter syndrome can lead a normal, healthy, and productive life.
Note: All information on KidsHealth® is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.
© 1995-2022 The Nemours Foundation. Nemours® and KidsHealth® are registered trademarks of the Nemours Foundation. All rights reserved.
Images provided by The Nemours Foundation, iStock, Getty Images, Veer, Shutterstock, and Clipart.com.

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использует защитную технологию, которая является устаревшей и уязвимой для атаки. Злоумышленник может легко выявить информацию, которая, как вы думали, находится в безопасности.

Human pheromones, on the other hand, are highly individualized, and not always noticeable. In 1986 Dr. Winifred Cutler, a biologist and behavioral endocrinologist, codiscovered pheromones in our underarms. She and her team of researchers found that once any overbearing underarm sweat was removed, what remained were the odorless materials containing the pheromones.
Dr. Cutler's original studies in the '70s showed that women who have regular sex with men have more regular menstrual cycles than women who have sporadic sex. Regular sex delayed the decline of estrogen and made women more fertile. This led the research team to look for what the man was providing in the equation. By 1986 they realized it was pheromones.
There's more on how pheromones affect women's menstrual cycles. Think back to college, or to growing up if you had sisters. Most women who live with or near other women adjust their menstrual cycle timing to each other. A recent study at the University of Chicago by Martha McClintock exposed a group of women to a whiff of perspiration from other women. It caused their menstrual cycles to speed up or slow down depending on the time in the month the sweat was collected -- before, during or after ovulation . This was the first proof that people produce and respond to pheromones.
Although it's now clear that pheromones exist, the way our body processes them has yet to be determined. Animals have a vomeronasal organ (VNO), which perceives the substance and then leads them to mate. Some anatomists don't think humans have a VNO; others think they've found pits inside our nostrils that might be VNOs, but may not work.
Despite the gap in our knowledge, these remarkable studies about pheromones and menstrual cycles have brought to light the idea that pheromones could be used as fertility treatments for couples who want to conceive, or as contraceptives for those who don't. And couples who are having sexual problems could use pheromones combined with traditional therapy to enhance desire. It's also possible, some researchers say, that pheromones could be a mood enhancer, alleviating depression and stress . And the most far-reaching hypothesis so far is that pheromone treatment could control prostate activity in men to reduce the risk of cancer .
If you're looking for the man or woman of your dreams , unsuspecting pheromones in your body scent are most likely playing a large and very clever role in mate attraction. According to an article in " Psychology Today," how our body odors are perceived as pleasant and sexy to another person is a highly selective process. We usually smell best to a person whose genetically based immunity to disease differs most from our own. This could benefit you in the long run, making for stronger, healthier children.
Seventy-four percent of the people who tested a commercial pheromone called Athena, developed by Dr. Cutler, experienced an increase in hugging, kissing and sexual intercourse. Maybe the best advice to those looking for a mate or wanting to take their relationship to a new level is to take a good long sniff!
Here's how to avoid the most common mistakes.
What do you know about locking lips?
© 2005 - 2022 WebMD LLC. All rights reserved.
WebMD does not provide medical advice, diagnosis or treatment.

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