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Cuenca where can I buy cocaine
The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Cocaine benzoylmethyl ecgonine is a crystalline tropane alkaloid that is obtained from the leaves of the coca. Cocaine is an addictive illegal drug 1. Spain has become the top consumer of cocaine in continental Europe, according to a recent European Union study on drug use. Specifically, it is a dopamine reuptake inhibitor, a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor 2. Cocaine is a potent central nervous system stimulant. Short-term cocaine effects include: increased blood pressure, constricted blood vessels, mental alertness, dilated pupils, increased energy, increased heart rate and temperature and decreased appetite 3 , 4. Cardiovascular and neurologic are the predominant alterations. Digestive complications are infrequent. Pancreatic involvement is exceptional and only isolated cases have been reported 2 , 5. A 21 years old boy with epilepsy treated with lamotrigine was accepted at hospital with abdominal pain radiated straight through to the back, nausea and vomiting. Blood urea, oxygen saturation, serum calcium, coagulation parameters and triglyceride levels were normal. The patient denied alcohol ingestion or drugs consumption. Abdominal ultrasonography excluded gallstones and dilatation of the bile duct. A spiral computed tomography with contrast performed within 48 hours showed diffuse enlargement of the pancreas with minimal ascites Grade B of Balthazar. Cholangiography MRI was normal. Urine drugs test was positive for cocaine and the patient admitted to use insufflated cocaine as a recreational drug. He had taken cocaine 48hours before abdominal pain started. Alcohol consumption was ruled out. Clinical evolution was positive without complications and the patient was discharged within 6 days. After hospitalization, he has been controlled every three months during two years without new events. Cocaine consumption seems to be the cause of acute pancreatitis in this patient. The absence of other recognized etologies, the antecedent of insufflated cocaine consumption in the last 48 hours and the elevated LDH serum values made cocaine to be the cause of acute pancreatitis in this young patient. Cocaine consumption cause several medical problems 6. Heart attack, arrhythmias, stroke and convulsions are the most frequent. Psychiatric, pulmonary and renal complications have been described. Intestinal ischemia 9 , 10 , perforation 7 , retroperitoneal fibrosis, gastric ulcer 8 has been described. Pancreatic involvement is exceptional and only very few cases have been reported. Most of acute pancreatitis are related with alcohol consumption or gallstones. Pancreatic ischemia causes acute pancreatitis too. Cocaine blocks the presynaptic reuptake of the neutotransmitters norepinephrine and dopamine. It also causes monoaminooxidases inhibition and it has a direct anticholinergic action. This way alpha- adrenergic receptors are highly stimulated. Activation of the sympathetic nervous system by this mechanism produces vasoconstriction and ischemia 8. ISSN: Previous article Next article. Issue 8. Pages October Export reference. More article options. DOI: Download PDF. Corresponding author. This item has received. Article information. Full Text. Autor para correspondencia. N Eng J Med, , pp. Gastroenterol Clin Biol, 27 , pp. An Med Intern, 7 , pp. N Engl J Med, , pp. An Med Intern, 13 , pp. Complications related with cocaine abuse that require hospital admission.. Rev Clin Esp, , pp. Gastroenterol Hepatol, 31 , pp. Gastrointestinal manifestations of cocaine addiction.. Int J Clin Pharmacol Ther, 32 , pp. Cocaine abuse and intestinal ischemia: case report and literature review.. Cir Esp, 73 , pp. Superior mesenteric and celiac trunk ischemia alter administration of cocaine.. Rev Esp Enf Dig, 98 , pp. Subscribe to our newsletter. Print Send to a friend Export reference Mendeley Statistics. Recommended articles. Characterizing Hepatitis Delta in Spain and the gaps in its Location, morphology and invasiveness of lateral spreading Article options. Download PDF Bibliography. Are you a health professional able to prescribe or dispense drugs? Characterizing Hepatitis Delta in Spain and the gaps in its management.
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