Cones, Bosko, Hashish Naxos
Cones, Bosko, Hashish Naxos______________
Наши контакты (Telegram):
>>>НАПИСАТЬ ОПЕРАТОРУ В ТЕЛЕГРАМ (ЖМИ СЮДА)<<<
_______________
ВНИМАНИЕ !!! ВАЖНО !!!
В Телеграм переходить только по ССЫЛКЕ что ВЫШЕ, в поиске НАС НЕТ там только фейки !!!
Чтобы телеграм открылся он у вас должен быть установлен!
_______________
ITALIA PIU' MARCH 2020
Reporting from:. Your name. Your email. Send Cancel. Toggle navigation Menu. Help Need help? Selections 0 Clear all lists. Name of resource. Problem URL. Describe the connection issue. Search settings. Toggle facets Refine your results. Source type. Academic Journals Journal title. Additional selections in this facet will expand rather than narrow your search result. View results as: View Normal Brief. Sort by relevance relevance date most recent date oldest. Microscopic and functional changes observed with dynamic optical coherence tomography for severe refractory atopic dermatitis treated with dupilumab. Background: Atopic dermatitis AD is a chronic inflammatory disease. Clinical scores of AD severity were assessed at baseline T0 and after 1 and 3 months of treatment T1, T2. The quality and quantity of peri-implant soft tissues at the crestal portion of dental implants are important aspects to consider for a long-term successful implant-supported rehabilitation. Some relevant factors attributed to the implant health include mucosal thickness and keratinization. In this respect, many techniques and materials have been described to augment and improve buccal peri-implant soft tissues. Over the last few years, newly developed xenogeneic collagen matrices have been introduced in peri-implant plastic surgery to replace autogenous soft tissue grafts; however, data remain controversial so far. Thus, the purpose of the present report was to present a novel surgical technique conceived to augment buccal peri-implant soft tissues in combination with a volume-stable porcine collagen matrix. The rationale and the fundamental concepts that led to the use of a xenogeneic matrix to increase soft tissue volumes were also discussed. The treatment of cutaneous viral warts caused by human papillomavirus HPV infection is often subject to local recurrence and a long clinical and treatment course. The questionnaire was designed to obtain detailed information on wart treatment and compare NZCS efficacy with previous treatments. NZCS showed better efficacy and tolerability than other previous wart treatments. Clinical relevance of the International Society for Heart and Lung Transplantation consensus classification of primary graft dysfunction after heart transplantation: Epidemiology, risk factors, and outcomes. In this 2-center study we analyze outcomes and risk factors of P-GD according to the recent consensus conference classification endorsed by International Society for Heart and Lung Transplantation. Methods We included all adult HTs performed between and P-GD was graded as mild, moderate, and severe, according to International Society for Heart and Lung Transplantation recommendations, and analyzed separately from secondary GD. The primary end point was the combined occurrence of in-hospital death or emergency retransplantation. The end point occurred in 53 patients Overall, GD was a strong predictor of death-graft loss odds ratio, Several known risk factors influenced the risk for P-GD, and the combination of specific donor and recipient risk factors accounted for approximately times increased odds for P-GD. Donor age, recipient diabetes, ischemic time, and post-operative dialysis predicted non-recovery from P-GD. The amplified negative effect of donor and recipient factors on P-GD risk underscores the need for appropriate donor-recipient match. Monocyte Distribution Width MDW , a new cytometric parameter correlating with cytomorphologic changes occurring upon massive monocyte activation, has recently emerged as promising early biomarker of sepsis. This pilot study shows that MDW can be useful in the monitoring of COVID patients, as this innovative hematologic biomarker is: 1 easy to obtain, 2 directly related to the activation state of a fundamental inflammatory cell subset i. Background: bone augmentation by means of manually shaped titanium mesh is an established procedure to regenerate atrophic alveolar ridges and recreate a proper contour of the peri-implant bone anatomy. Conversely, current literature on the use of preformed titanium meshes instead of traditional grids remains lacking. Therefore, the aim of the present prospective study was to evaluate the use of preformed titanium mesh to support bone regeneration simultaneously to implant placement at dehiscence-type defects from clinical, radiological, and patient-related outcomes. Methods: 8 implants showing buccal dehiscence defects were treated with preformed titanium mesh directly fixed to flat abutments screwed to the implant. Intrasurgical clinical measurements and radiographic evaluations by means of cone-beam computed tomography scans were performed to assess the horizontal bone gain after 8 months from the augmentation surgery. Biological and patient-centered outcomes were also evaluated. A mean horizontal bone gain of 5. From a macroscopic aspect, the remodeled graft appeared well integrated with the host bone. Well vascularized newly formed bone-like tissue was observed in intimate contact with the implants. Conclusions: preformed titanium mesh may be effective in supporting simultaneous horizontal bone regeneration at dehiscence-type peri-implant defects. Titanium mesh exposure still remain an issue in this type of surgery. Psychobiological responses to unpleasant emotions in cannabis users. Aim of this paper is to investigate the psychobiological reactions to experimentally induced negative emotional states in active marijuana-dependent smokers and whether changes in emotional reactivity were reversed by prolonged abstinence. Twenty-eight patients were randomly included into group A fourteen active marijuana-dependent smokers or group B fourteen abstinent marijuana-dependent subjects. Emotional response evaluation of group B subjects was assessed after 6 months of abstinence. Fourteen healthy volunteers, matched for age and sex, were used as controls. Neutral and unpleasant set of pictures selected from the international affective picture system and the Self-Assesment Manikin procedure SAM have been used to determine ratings of pleasure and arousal. Before and after the experimental session, blood samples were collected to determine ACTH and cortisol plasma levels. Active cannabis users displayed significantly higher levels of pleasantness SAM scores and lower levels of arousal SAM scores compared to abstinent cannabis users and controls in response to emotional task. In a close parallel with psychological data, hormonal findings indicate a persistent hyperactivity of hypothalamus-pituitary-adrenal HPA axis in cannabis users, particularly among active marijuana smokers, and an impaired hormonal reaction to negative emotions, in comparison with healthy subjects. Ours findings, although obtained in a small number of subjects, suggest an association between active cannabis use, subjective reduced sensitivity to negative emotions and threat and HPA axis dysfunction. Although different studies have been undertaken to investigate the timing of the onset of major cardiovascular events, no data exist on temporal patterns of the onset of CH in subjects treated with OACs. Age, sex, time and location of the hemorrhagic lesion, type of the bleeding events idiopathic or post-traumatic , anticoagulant therapy warfarin or new oral anticoagulants - NOAs and time of ED admission i. Five hundred and seventeen patients Warfarin was taken by patients In-hospital mortality IHM was recorded in cases Cosinor analysis showed a peak of CH arrival between and h both in the whole population PR A further analysis between idiopathic and post-traumatic CH confirmed the presence of a 24 h pattern with a peak between and h PR A letter to the editor about Takotsubo cardiomyopathy TTC is presented. Introduction: An optimal aesthetic implant restoration is a combination of a visually pleasing prosthesis and adequate surrounding peri-implant soft tissue architecture. This study describes a novel workflow for one-step formation of the supra-implant emergence profile. Materials and Methods: Two randomized groups were selected. Ten control group participants received standard healing screws at the surgical stage. The modified healing abutment shape was extracted from a virtual library. The standard triangulation language STL files of a premolar and a molar were obtained considering the coronal anatomy up to the cement-enamel junction CEJ. After a healing period ranging from 1 to 3 months depending on the location of the surgical site, namely, mandible or maxilla, a digital impression was taken. In the test group, pain assessment at crown placement presented a mean value of 0. On the contrary, the control group showed a mean value of 5. Efficient automatic classifiers for the detection of A phases of the cyclic alternating pattern in sleep. This study aims to develop an automatic detector of the A phases of the cyclic alternating pattern, periodic activity that generally occurs during non-REM NREM sleep. Eight polysomnographic recordings from healthy subjects were examined. From EEG recordings, five band descriptors, an activity descriptor and a variance descriptor were extracted and used to train different machine-learning algorithms. A visual scoring provided by an expert clinician was used as golden standard. Four alternative mathematical machine-learning techniques were implemented: 1 discriminant classifier, 2 support vector machines, 3 adaptive boosting, and 4 supervised artificial neural network. The results of the classification, compared with the visual analysis, showed average accuracies equal to The SVM leads to accuracy of The performance achieved by the automatic classification is encouraging, since an efficient automatic classifier would benefit the practice in everyday clinics, preventing the physician from the time-consuming activity of the visually scoring of the sleep microstructure over whole 8-h sleep recordings. Finally, the classification based on learning algorithms would provide an objective criterion, overcoming the problems of inter-scorer disagreement. Characterization of A phases during the Cyclic Alternating Pattern of sleep \\\\\\\\\[\\\\\\\\\]. Nine descriptors were computed: band descriptors low delta, high delta, theta, alpha, sigma and beta ; Hjorth activity in the low delta and high delta bands; differential variance of the EEG signal. The information content of each descriptor in recognizing the A phases was evaluated through the computation of the ROC curves and the statistics sensitivity, specificity and accuracy. Results: The ROC curves show that all the descriptors have a certain significance in characterizing A phases. The average accuracy obtained by thresholding the descriptors ranges from Conclusions: The results show that it is possible to attribute a significant quantitative value to the information content of the descriptors. Significance: This study gives a mathematical confirm to the features of CAP generally described qualitatively, and puts the bases for the creation of automatic detection methods. Temporomandibular disorders TMDs involve a heterogeneous group of clinical conditions affecting the stomatognathic system and its related structures. Because the etiology of these disorders is still unclear, a wide range of therapeutic solutions has been proposed in the literature, including occlusal appliances, physical therapies, drugs, and biobehavioral modalities. Biobehavioral therapy could have a beneficial effect in the treatment of TMDs because of the reportedly high prevalence of psychological dysfunction in TMD patients. The authors reviewed the biobehavioral modalities used to achieve pain relief in patients affected by such disorders, with the aim of synthesizing data on the effectiveness these therapeutic approaches. Literature data suggest that the inclusion of biobehavioral interventions in the management of TMDs may be reasonable, even if no conclusions can be drawn about their long-term effectiveness. Mood disorders in subjects with bruxing behavior \\\\\\\\\[\\\\\\\\\]. Summary: Objective: An investigation was conducted on subjects to assess the existence of an association between mood psychopathology and bruxism. Methods: Validated clinical criteria were used to diagnose bruxism and a self-report validated questionnaire MOODS-SR was filled out by each patient for an evaluation of depression and mania symptoms of mood spectrum. Conclusions: Support to the existence of an association between bruxism and mood disorders has been provided. Further studies are strongly needed to clarify mechanisms underlying the described association. The rapid evolution of Next Generation Sequencing in clinical settings, and the resulting challenge of variant reinterpretation given the constantly updated information, require robust data management systems and organized approaches. In this paper, we present iVar: a freely available and highly customizable tool with a user-friendly web interface. It represents a platform for the unified management of variants identified by different sequencing technologies. Updated annotations can be periodically re-uploaded and associated with variants as historically tracked attributes, i. Data can be visualized through variant-centered and sample-centered interfaces. A customizable search function can be exploited to periodically check if pathogenicity-related data of a variant has changed over time. Patient recontacting ensuing from variant reinterpretation is made easier by iVar through the effective identification of all patients present in the database carrying a specific variant. We tested iVar by uploading VCF files and annotation files, obtaining a database of samples and 22, unique variants. Next-generation sequencing NGS -based cancer risk screening with multigene panels has become the most successful method for programming cancer prevention strategies. ATM germ-line heterozygosity has been described to increase tumor susceptibility. In particular, families carrying heterozygous germ-line variants of ATM gene have a 5- to 9-fold risk of developing breast cancer. Nowadays, more than missense variants and several truncating mutations have been identified in ATM gene. This work locuses on the microwave-assisted hydrothermal synthesis of praseodymium-doped zirconia and on the subsequent evaluation of the effect of synthesis conditions on powder properties. At atomic scale, as determined from perturbed angular correlation data, the XRI amorphous fraction of the as-obtained powders exhibits a tetragonal-like structure. The pure powder becomes partially stabilized and the doped powder is a substitutional solid solution of praseodymium in tetragonal zirconia. Sexual hormone serum levels and temporomandibular disorders. A preliminary study. In female patients, blood samples were collected in follicular and luteal phases of the same menstrual cycle, while only one blood sample was drawn in male patients. Serum levels of estradiol and progesterone were determined using a radioimmunoassay and the comparison between the two groups was performed using a t test. Considering the multifactorial etiology of TMD and the hypothesis that some joint tissues e. Reply \\\\\\\\\[\\\\\\\\\]. See catalog results. Guides Course- and topic-based guides to collections, tools, and services. Search '''Manfredini, Mario.