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Cocaine use produces behavioural alterations and cause psychotic symptoms, in some cases can induce paranoia and physical dependence. Cocaine binds to monoamine transporters thereby blocking transmitter reuptake, and its psychostimulant properties are the result of increase in synaptic levels of dopamine, serotonin and norepinephrine. Some people have a greater risk of becoming addicted to cocaine and at a genetic level; one of the possible causes of this susceptibility would be the presence of polymorphisms that affect genes involved in the regulation of the neuronal reward circuit. Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information. We use our own and third party cookies to analyze our services and show you advertising related to your preferences based on a profile developed from your browsing habits. Close Privacy Overview This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are as essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience. Necessary Necessary.

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