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A pragmatic, 4-week, 4-group, between-subjects, factorial randomised controlled trial conducted at a specialist NHS outpatient addictions clinic and hospital clinical research facility to determine if mental imagery of past and future positive \\\\\\\\\\\\\[recovery oriented\\\\\\\\\\\\\] and negative \\\\\\\\\\\\\[cocaine aversive\\\\\\\\\\\\\] events can help reduce cue-induced cocaine craving and cocaine use. Cocaine, a powerful stimulant drug, is used by 2. There are currently no approved medication-assisted treatments or specific psychosocial interventions for CUD. For many people, repeated administration of cocaine over a short duration of time creates vivid episodic memories of euphoria which can inform future craving content. Craving or strong urges are a distinctive feature of CUD and are often reported as involuntary, distressing and uncontrollable. Research has demonstrated that craving experiences can be voluntarily evoked or elicited by conditioned drug cues in the environment and internal processes such mood or physical sensations. The associations between cues and use are established through classical and instrumental reward-based conditioning and are important for the development and maintenance of CUD. Enhanced attention to cocaine cues develops and remains heightened for at least six months into abstinence. Craving-related experiences are informed by memories of intense reward, physical sensations and include pro-drug beliefs, appraisals, expectancies and vivid mental imagery. Drug-imagery is often initially pleasurable and affectively charged and can motivate drug-seeking behaviour. If impeded or delayed, drug imagery highlights a deficit and can be experienced as distressing and intrusive. Treatment of intrusive images has been successful in various psychological disorders using imagery rescripting. Imagery rescripting has recently been used in memory-focused cognitive therapy to help reduce cocaine craving. Reducing intrusive image-induced negative affect through positive imagery is important for relieving psychological distress but there is also evidence that aversive imagery may reduce maladaptive approach behaviours. This will be a pragmatic, 4-week, 2x2, between-subjects, factorial randomised controlled trial. Informed consenting adult participants will be randomised to one of four conditions: - future-based prospective recovery-oriented imagery; - future-based prospective cocaine-aversive imagery; - past autobiographical recovery-oriented imagery; or - past autobiographical cocaine-aversive imagery. Participants will undergo a craving induction procedure designed to elicit cue-induced craving. In response to elevated craving, participants will be asked to reduce their craving levels using a mental imagery intervention. Following the procedure in the research facility, participants will be given a digital audio player to take home. This will contain a recording of the imagery condition they are allocated to. Participants will be asked to listen to this recording each day during a day follow-up, and ad libertatem when experiencing cocaine craving. After 14 days participants will be invited for a follow up conducted at the community addictions clinic. Название вмешательства: Mental Imagery for Craving Reduction. Описание: a behavioural mental imagery intervention where participants are asked to generate specific mental images to reduce cue-induced craving for cocaine use disorder. Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a future without cocaine use. Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a future where cocaine is causing significant distress. Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a past event without cocaine use. Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a past event where cocaine use has caused significant distress. This information was retrieved directly from the website clinicaltrials. If you have any requests to change, remove or update your study details, please contact \\\\\\\\\\\\\[email protected\\\\\\\\\\\\\]. As soon as a change is implemented on clinicaltrials. Разрешить куки Управление настройками. Разрешить рекламу и аналитику Нет Да Создайте персонализированный рекламный профиль Нет Да Создайте персонализированный профиль контента Нет Да Выберите персонализированный контент Нет Да Измеряйте эффективность рекламы Нет Да Измеряйте эффективность контента Нет Да Применяйте маркетинговые исследования, чтобы получить представление об аудитории Нет Да Разрабатывать и улучшать продукты Нет Да Обеспечение безопасности, предотвращение мошенничества и отладка Нет Да Технически доставлять рекламу или контент Нет Да. Разрешить куки Сохранить настройки. Study to test Levothyroxine Formulation in Hypothyroid Patients. BTL Industries Ltd started a new clinical trial for toning of buttocks. Cocaine Use Disorder. Тип вмешательства: Behavioral Название вмешательства: Mental Imagery for Craving Reduction Описание: a behavioural mental imagery intervention where participants are asked to generate specific mental images to reduce cue-induced craving for cocaine use disorder. Фамилия: Camille Goetz Телефон: Эл. Метка: Future-based recovery-oriented imagery Тип: Experimental Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a future without cocaine use Метка: Future-based cocaine-aversive imagery Тип: Experimental Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a future where cocaine is causing significant distress Метка: Past recovery-oriented imagery Тип: Experimental Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a past event without cocaine use Метка: Past cocaine-aversive imagery Тип: Experimental Описание: Mental Imagery for Craving Reduction: mental imagery aimed at describing a past event where cocaine use has caused significant distress.

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