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Prof Tsatsakis has published well over works articles in journals, books and abstracts proceedings , over of them in ISI journals. Prof Tsatsakis has given over keynote and plenary lectures in international congresses and has been the promoter and chair of numerous Symposiums and workshops in International Forum. He has coordinated as a PI in over 60 scientific research and technology projects and has established worldwide collaborations. Tsatsakis has a long-standing activity as Editor in toxicology journals, he is currently Editor in chief of Toxicology Reports and editor of Food and Chemical Toxicology and has served as editor and guest editor in many other journals, such as Toxicology, Food and Chemical Toxicology, Toxicology Letters. The main research interests of Professor Tsatsakis include biomonitoring and risk assessments of xenobiotics as well as links of chronic exposure to them at low doses with health problems and diseases. He developed numerous biomarkers of exposure and of effects for various chemicals, in particular pesticides, pharmaceuticals, etc. His motivation and basic concept highlights the important role of academia involvement in social life problems. The postulation of real-life risks simulation based on low dose combined long term exposures related to health issues, is a crucial element and the central driving force for application of theory to practice on safety evaluations in 21 century. Katsikantami I. Estimation of daily intake and risk assessment of organophosphorus pesticides based on biomonitoring data — The internal exposure approach. Food Chem. Toxicol, , 57— Kouretas D. Editorial: Alternative tobacco products: Toxicology and health issues. Buha A. Overview of cadmium thyroid disrupting effects and mechanisms. Imtiaz M. Physiological and anthocyanin biosynthesis genes response induced by vanadium stress in mustard genotypes with distinct photosynthetic activity. Docea A. Veremchuk, L. Impact evaluation of environmental factors on respiratory function of asthma patients living in urban territory. Surichan S. Front Pharmacol. Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity. Int J Oncol. Environmental impacts of genetically modified plants: A review. Environ Res. Quantification of 4-Methylimidazole in soft drinks, sauces and vinegars of Greek market using two liquid chromatography techniques. Food ChemToxicol. Resveratrol as MDR reversion molecule in breast cancer: An overview. Human exposure to chemical mixtures: Challenges for the integration of toxicology with epidemiology data in risk assessment. Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study. Environmental metal contamination and health impact assessment in two industrial regions of Romania. Sci Total Environ. Amphiphilic poly-N-vinylpyrrolidone nanoparticles as carriers for non-steroidal, anti-inflammatory drugs: In vitro cytotoxicity and in vivo acute toxicity study. Basophil mediated pro-allergic inflammation in vehicle-emitted particles exposure. A global assessment of phthalates burden and related links to health effects. Environ Int. Toxicological and efficacy assessment of post-transition metal Indium phthalocyanine for photodynamic therapy in neuroblastoma. Amphiphilic poly-Nvynilpyrrolidone nanoparticles: Cytotoxicity and acute toxicity study. Protein bio-corona: critical issue in immune nanotoxicology. Arch Toxicol. Sex differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma. Nephrotoxicity in rabbits after long-term nandrolonedecanoate administration. Toxicol Lett. Long-term exposure to cypermethrin and piperonylbutoxide cause liver and kidney inflammation and induce genotoxicity in New Zealand white male rabbits. Toxicology as an academic discipline in European Universities. Int JOncol. Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics. Longterm exposure of rabbits to imidaclorpid as quantified in blood induces genotoxic effect. Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use Review. Cardiotoxicity in rabbits after long-term nandrolonedecanoate administration. Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. Natural products-friends or foes? Cancer microenvironment and inflammation: role of hyaluronan. Front Immunol. Biomonitoring of bisphenol A in hair of Greek population. Oxid Med Cell Longev. Environmental contaminants and target organ toxicities - new insights into old problems. Anthracycline-dependent cardiotoxicity and extracellular matrix remodeling. Antioxidant effects of whey protein on muscle C2C12 cells. Biomonitoring of dialkylphosphate metabolites DAPs in urine and hair samples of sprayers and rural residents of Crete, Greece. Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants. Benzo\\\\\\\\\\\\\[a\\\\\\\\\\\\\]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorinmethyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism. Role of oxidative stress in chemical allergens induced skin cells activation. Could growth factor-mediated extracellular matrix deposition and degradation offer the ground for directed pharmacological targeting in fibrosarcoma? Curr Med Chem. Emerging health issues from chronic pesticide exposure: innovative methodologies and effects on molecular cell and tissue level. Cancer Lett. Role of paraoxonase 1 PON1 in organophosphate metabolism: implications in neurodegenerative diseases. A case report of motor neuron disease in a patient showing significant level of DDTs, HCHs and organophosphate metabolites in hair as well as levels of hexane and toluene in blood. Anticancer effects of the metabolic products of the resveratrol analogue, DMU structural requirements for potency. Eur J Med Chem. Determination of operator exposure levels to insecticide during bait applications in olive trees: study of coverall performance and duration of application. Int J Hyg Environ Health. Pediatr AllergyImmunol. J Lipid Res. Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P CYP1 enzymes. Biological evidence for the acute health effects of secondhand smoke exposure. Acute and short-term effects of secondhand smoke on lung function and cytokine production. Decorin-induced growth inhibition is overcome through protracted expression and activation of epidermal growth factor receptors in osteosarcoma cells. Mol Cancer Res. Regulation of hyaluronan and versican deposition by growth factors in fibrosarcoma cell lines. A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion. J ClinEndocrinolMetab. Penetration of newer quinolones in the empyema fluid. EurRespir J. Use of L-lysine fluorescence derivatives as tracers to enhance the performance of polarization fluoroimmunoassays. A study using two herbicides as model antigens. Anal Chem. Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification. Mammographic findings and occupational exposure to pesticides currently in use on Crete. Eur J Cancer. An anaemic infant in a coma. Pesticides Exposure and Risk of Hypospadias. In: Pesticides. Formulations, Effects, Fate. ISBN: , Viena, , pp. Tsatsakis A. New synthetic plant growth regulators. Proceedings Plant Morphogenesis: Molecular approaches K. Roubelakis- Angelakis and K. Tran Thanh Van, eds, Plenum Publ. Selected Proceedings and Abstracts. Tzatzarakis, C. Girvalaki, A. Vardavas, P. Stivaktakis, A. Nosyrev, G. Leon, A. Tsatsakis, C. Evaluation of e-cigarette liquid on labeling, packaging and technical features prior the adoption of the Tobacco Products Directive TPD in multiple European countries. Liesivuori J. Introduction to Social Toxicology. Katsikantami, V. Karzi, M. Tzatzarakis, E. Vakonaki, A. Stavroulaki, P. Xezonaki, S. Sifakis, A. Tsatsakis, A. Fragiadoulaki, P. Kalogeraki, I. Tsiaousis, A. Kalliantasi, A. Stratidakis, V. Karzi, C. Mamoulakis, A. Micronuclei frequency and blood cell number in a rabbit contrast-induced nephrotoxicity model with antioxidants as a preventive strategy. Apalaki, A. Kalliantasi, T. Nikolouzakis, I. Fragkiadoulaki, P. Stivaktakis, F. Karkala, G. Vaki, J. Tsiaoussis, A. The frequency of micronuclei, subsequent to administration of chemotherapeutic medicines in colon and rectal cancer. Vardavas, E. Ozcagli, P. Fragkiadaki, P. Stivaktakis, M. Tzatzarakis, K. Kaloudis, M. Tsardi, G. Datseri, J. Tsiaoussis, C. Tsitsimpikou, F. Carvalho, A. Tsatsakis, DNA damage after long-term exposure of rabbits to Imidacloprid and sodium tungstate, Toxicol. Tsatsakis, Biomonitoring of pesticides exposure for linking to diseases: The current status, problems and future needs, Toxicol. Tzatzarakis, V. Karzi, E. Vakonaki, E. Barbounis, C. Tsitsimpikou, A. Vardavas, I. Tsakiris, S. Psycharakis, A. Rizos, A. Tsatsakis, Bisphenol A in beverages and canned foods of the Greek market, Toxicol. Vakonaki, C. Kampouropoulou, P. Stivaktakis, S. Papachristou, D. Vynias, I. Tsakiris, A. Tsatsakis, Determination of diacetyl in butters and margarines by gas chromatography—mass spectrometry, Toxicol. Tsakiris, M. Tzatzarakis, A. Alegakis, P. Mitlianga, E. Vakonaki, I. Tsatsakis, J. Dumanov, D. Sarigiannis, A. Vakonaki, M. Kavvalakis, P. Stivaktakis, I. Heretis, E. Barbounis, A. Vardavas, M. Barmpas, A. Kavvalakis, M. Tzatzarakis, P. Bariotaki, A. Tsakalof, A. Vardavas, F. Babatsikou, D. Vynias, A. Mitlianga, M. Kavvalakis, E. Goumenou, P. Tsatsakis, Monitoring of pesticides residues in Greek bottled wine, Toxicol. Persefoni, T. Christina, V. Fotini, S. Polychronis, S. John, T. Konstantinos, T. Maria, K. Demetrios, T. Aristidis, Histopathological findings, telomerase activity and oxidative stress in kidney tissue after long-term rabbits exposure to turinabol and methanabol, Toxicol. Morozova, E. Vakonaki, S. Petrochenko, M. Myagkova, E. Kanaki, S. Belivanis, A. Tsatsakis, Detection of antibodies in serum of drug users after an abstinence period of opiates use, Toxicol. Tzatzarakis, M. Savvopoulos, M. Kavvalakis, I. Nagaev, L. Kovatsi, S. Belivanis, E. Koutras, I. Nestoros, A. Tsatsakis, Comparative evaluation of deposition of cannabinoids, opiates and cocaine in hair samples from different anatomical sites, Toxicol. Stivaktakis, G. Maravgakis, M. Alegakis, E. Theodoropoulou, M. Kokkinakis, J. Liesivuori, A. Tsatsakis, Micronucleus assay in rabbits: A genotoxicity study of sub-acute levels of imidacloprid, Toxicol. Chorti, K. Poulianiti, A. Jamurtas, K. Kostikas, M. Tzatzarakis, D. Vynias, Y. Koutedakis, A. Flouris, A. Tsatsakis, Effects of active and passive electronic and tobacco cigarette smoking on lung function, Toxicol. Tsakiris, C. Dionysopoulou, M. Alegakis, M. Kokkinakis, E. Theodoropoulou, P. Mitlianga, J. Tsatsakis, Monitoring organochlorine metabolites in dietary milk and estimation of hazard index values, Toxicol. Tsatsakis, Pesticide exposure and health related issues in male and female reproductive system. Biomarkers of exposure and effects on pregnancy. Favas, A. Tsatsakis, M. Kokkinakis, M. Mparbounis, A. Alegkakis, P. Mitliagka, F. Papathanasiou, N. Niklis, Frequency and severity estimation of pesticide residues from organically cultivated olives and olive tree leafs in Greece, during , Toxicol. Detection of non specific organophosphate pesticide metabolites in human hair samples. Alegakis, A. Zafiropoulos, G. Tzanakakis, J. Liesivuori, C. Koutis, A. Principles and applications of capillary electrophoresis and microchips in forensic and clinical toxicology. Thesis: Synthesis and reactivity studies in the series of mercaptomethyl carboxy and methoxy carboxy derivatives of naphtalene. Advisor: Lisitsyn VN. Thesis: Chemical transformations and bioactivity of 2,7- and 2,6- naphthalene thio oxy acetic acids. Engineering, Mendeleyev University of Chemistry, Moscow. Nanomedicine - Nanotoxicology. New Water-soluble polymeric plant growth regulators. Hellenic Industrial Property Organisation. Water soluble polymeric systems of phytohormones with slow release Synthesis and application. No Controlled release drug systems: New water-soluble polymeric derivatives of indomethacine. Hellenic Industrial Property Organisation No , Pharmaceutical compositions: Bandages with immobilised sustained indomethacin formulation. Patent No , New antifungal agents with prolonged action. Methods of preparation and pharmaceutical formulation of non water soluble biologically active compounds. Russian Patent. Novel macroporous hydrogel systems. Preparation, properties and applications. Water-compatible polymer compositions for delivery of biologically active substances. Aristidis Michael Tsatsakis Professor. Organizing committee. University of Crete. ISBN: , Viena, , pp 6. Karamanos

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