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Medical Fraud, Mislabeling, Contamination: All Common in CBD Products
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Official websites use. Share sensitive information only on official, secure websites. Cannabidiol CBD is an oil derived from the cannabis plant. People are consuming it under the misapprehension that it is safe, however, CBD has negative side effects and may interfere with the functioning of other medications and may be contaminated. Consumer demand for CBD has increased due to aggressive marketing and fraudulent health claims. In the rush to market CBD, there has been little consideration of the concerns that must be addressed before CBD is given full acceptance. This article will explore those concerns. There are claims that CBD from hemp used as a medicine or food is always legal. This is not accurate. The Agriculture Improvement Act of changed federal law regarding the production and marketing of hemp. Hemp is defined as cannabis and its derivatives with extremely low less than 0. These changes removed hemp from the federal Controlled Substances Act, which means that it will no longer be an illegal substance under federal law. These compounds are subject to the same requirements as FDA-regulated products containing any other substance regardless of the source of the substance. This deceptive marketing of unproven treatments raises significant public health concerns, as it may keep some patients from accessing appropriate, recognized therapies to treat serious and even fatal diseases. Black-market CBD products have not been evaluated by the FDA to determine if they are safe as foods or effective or safe for any medical use, and if safe, what the proper dosage would be. In addition, they are not administered with any federally approved medical protocols as are prescription drugs and there may be no warnings for how they interact with other drugs, or whether they have dangerous side effects. Its approval was based on well-controlled FDA clinical trials. This is a purified form of CBD in a reliable dosage form and a reproducible route of delivery. Since it is manufactured according to FDA standards by a reliable company that has followed the rules, we can assume it is free from adulterants and contaminants. Its side effects and other clinical data are publicly available. This type of data is not provided by the black-market CBD products. There are a number of papers discussing the pros and cons of CBD as a medicine that can be viewed on the National Library of Medicine website at www. Some studies, notwithstanding their many deficiencies, provide some support for the hypothesis that CBD may exert some beneficial effects, but is has yet to be proven to be both effective and safe. Studies suggest that black-market CBD is not very reliable or safe. There were other defects in the mislabeled products. Only Accuracy of labeling depended on product type, with vaporization liquid most frequently mislabeled THC was detected up to 6. Only one product had a 1-to-1 ratio, which some research suggests is associated with fewer side effects and improved clinical benefit compared with higher ratios of THC to CBD. The testing indicated the edible cannabis products may have very little CBD. Oil based products also had a higher range of concentration. This study also notes that products containing THC could have sufficient enough concentrations to produce intoxication in children. Lead can cause poisoning, speech, and language problems, neurologic toxicity, and reproductive problems. Mold can cause allergic and respiratory problems, and yeasts can cause infection in people with compromised immune systems. The recall noted that acute lead poisoning could cause pain, muscle weakness, paresthesia, abdominal pain, nausea, vomiting, diarrhea, constipation, poor appetite, weight loss, symptoms associated with encephalitis, metallic taste in the mouth, shock, hemolysis, and kidney damage. In order to make claims of treatment or medical use, products must obtain approval from the FDA after submitting their data. There may be interactions between CBD and immunosuppressive drugs used in transplants or chemotherapy and with warfarin as there may be the potentiation of anticoagulant effects with marijuana, including CBD. CBD may interact with other medicines, including prescription and over-the-counter medicines, vitamins, herbal supplements, and any cannabis-based products. CBD may decrease how fast the liver metabolizes the drug. This may possibly increase the effects and side effects. CBD may potentially interact in a negative way with anti-epileptic drugs such as: carbamazepine Tegretol , phenytoin Dilantin , phenobarbital Luminal, Solfoton, Tedral , primidone anti-seizure. Users should be cautious before taking CBD with: sedatives, herbs, and supplements that cause drowsiness, seizure medications, drugs that are broken down and changed by the liver. The adverse reactions to CBD include: hepatocellular injury, somnolence and sedation, suicidal behavior and ideation, hypersensitivity reactions—allergic reactions, negative interaction with anti-epilepsy drugs such as Tegretol, Dilantin, luminal, Solfoton, Tedral, primidone , interactions with immunosuppressive drugs used in transplants or chemotherapy and with warfarin. CBD use can impair kidney function and cause anemia. The side effects of CBD can include: drowsiness, decreased appetite, diarrhea, transaminase elevations, fatigue, feeling unwell malaise , rash, difficulty sleeping insomnia, disordered sleep, and poor-quality sleep , infections, somnolence, decreased appetite, diarrhea, and asthenia. The research challenged the widely accepted premise that CBD is not intoxicating. High eye pressure is the primary risk factor for glaucoma, a leading cause of blindness. Although glaucoma is a listed indication for issuing sham medical marijuana cards, the most recent evidence is that cannabis in either tetrahydrocannabinol THC or cannabidiol CBD are both harmful to the eye and have a deleterious effect on glaucoma. Chronic cannabis use causes damage and loss of retina ganglion cells as does the disease glaucoma. Moreover, ganglion cells are central nervous system tissue, like the cells of the brain, and may serve as a surrogate marker for brain cell loss. This might account for neurological problems associated with heavy cannabis use such as memory loss, lethargy, and poor motivation, permanent IQ loss in youthful users, aggression, psychosis, etc. Half a century of research has found no benefit to any cannabis products in ophthalmology. Use of sham medical marijuana, CBD, or any form of cannabis is not recommended for glaucoma or any other eye condition by the American Academy of Ophthalmology or the Glaucoma Society. No physician should ever recommend cannabis use for any of the many forms of glaucoma. Black Market CBD may be sold without warnings being provided. People should be warned about the known adverse reactions to CBD. People should be cautioned about operating hazardous machinery, including motor vehicles, until they are reasonably certain that CBD does not affect them adversely e. Use of CBD may increase the risk of suicidal thoughts and behavior. Hypersensitivity reactions can occur with use of CBD. It is not known if CBD is safe and effective in children under two years of age. CBD for elderly persons could be dangerous due to the greater frequency of decreased liver or cardiac function, and of concomitant disease or other drug therapy. They may put themselves or their baby at serious risk by using these marijuana products. CBD products may also be contaminated with substances that may pose a risk to the fetus or breastfed baby such as pesticides, heavy metals, bacteria, and fungus. Studies in laboratory animals show male reproductive toxicity, including in the male offspring of CBD-treated pregnant females. This includes decrease in testicular size, inhibition of sperm development, and decreased testosterone. CBD may affect drug test results. There are many recent lawsuits filed against CBD manufacturers and more are on the way. A California case claims that the company engaged in false and deceptive practices and that their products could not be sold legally. A California case claimed that the defendant company made false claims that CBD could help the symptoms of autism and that could treat illnesses such as hepatitis, cancer, and Tourette syndrome. A New York case alleges false medical claims for marijuana and for violations of the federal securities laws. The FDA is currently undertaking a large long-term study of black-market CBD products to understand the characteristics of CBD products in order to make informed decisions about how best to protect public health. The FDA will report again on the results from both the near and long-term studies when complete data sets are available. David G. CIVEL educates lawyers on the legal rights of the victims of the marijuana industry. This article should not be considered legal or medical advice. This is for informational purposes only. Use of and access to these materials does not in itself create an attorney-client, or any professional relationship, between David G. The readers should consult the study and make their own interpretation as to its accuracy. Be advised that case law and statutory and regulatory laws cited herein may have been amended or changed by publication date. As a library, NLM provides access to scientific literature. Mo Med. Find articles by David G Evans. Copyright by the Missouri State Medical Association. Open in a new tab. Disclosure This article should not be considered legal or medical advice. Similar articles. Add to Collections. Create a new collection. Add to an existing collection. Choose a collection Unable to load your collection due to an error Please try again. Add Cancel.
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