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Czech Republic: Most patients do not have the financial means to buy cannabis from the pharmacies. The Czech Republic legalized the medical use of cannabis this year becoming effective on 1 April, but maintained strict restrictions on growing, selling and importing it. For most patients the solution is still growing the plant themselves. Some 20, patients who are estimated to be eligible for cannabis treatment have no chance to get it legally - although so far police have largely ignored renegade growers who technically would face prison. Patients and medical experts blame interference by the Health Ministry, which has long fiercely opposed legalizing the medical use of cannabis. The ministry denies deliberately blocking access to medical cannabis, but few question that its policies have raised steep barriers for patients to access cannabis legally. The Health Ministry banned health insurance companies from covering the cost of medical cannabis, and set the maximum amount patients are allowed at 30 grams per month, an amount Zabransky says often falls woefully short of providing effective relief. The government also allowed imports of just four types of cannabis that can be obtained only from the Netherlands, where it is produced by the company Bedrocan, at a cost of about 10 US dollars about 7. Associated Press of 15 November Food and Drug Administration FDA has allowed the conduction of clinical studies with Epidiolex, their cannabis extract that contains Cannabidiol CBD as its active ingredient, for use in treating children with Dravet syndrome, a rare and severe form of infantile-onset, genetic, drug-resistant epilepsy syndrome. The company hopes to start the trials in To date, a total of children with epilepsy receive this medication. Press release by GW Pharmaceuticals of 15 November In pain patients oral THC dronabinol caused similar psychoactive effects to the intake of dronabinol by inhalation of cannabis. Scientists performed a randomized controlled trial of single dose placebo, 10 or 20 mg oral THC in 30 chronic non-cancer pain patients taking opioids and not using cannabis. ARCI peak effects at 2 hours were similar to peak effects of smoked cannabis at 30 minutes. Clin J Pain. Switzerland: Sativex will be available soon GW Pharmaceuticals announced that the company received marketing authorization for their cannabis extract Sativex for the treatment of spasticity in multiple sclerosis. Press release by GW Pharmaceuticals of 27 November Australia: Government of New South Wales rejects proposal for medical use of cannabis Last November the NSW government established a parliamentary inquiry into the use of cannabis for medical purposes. The committee recommended AIDS and terminally ill patients be allowed to possess and use up to 15 grams of dry cannabis. However the NSW government has rejected the proposal. Rheumatology Update of 22 November Amada N, et al. PeerJ ;1:e There was a negative correlation between the number of CB2 receptors in the spinal cord and severity of joint damage. Burston JJ, et al. PLoS One ;8 11 :e These medications are intended for use in osteoporosis. Kumar P, et al. Biochem Biophys Res Commun. In another 1. Ahlner J, et al. Scand J Public Health. Posttraumatic stress disorder was associated with alterations of the endocannabinoid oleoylethanolamide. Schaefer C, et al. Luteolin is a flavonoid present in many plants such as celery, green pepper and olive oil. Impellizzeri D, et al. Arthritis Res Ther ;15 6 :R Cannabidiol CBD , anandamide and hydrocortisone reduced the damage of the bowel mucosa caused by interleukin 17A. Harvey BS, et al. Regular members can sign up for the new member area of the IACM to access exclusive content. You need to become a regular member of the IACM to access the new member area. Online Events

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