RNA participates in all the aspects of the cell life cycle, and often mis-regulation leads to disease. Recent advances in understanding of RNA biochemistry, structure and dynamics have revealed the importance of RNA structure in cellular processes and disease. NMR spectroscopy is a unique and powerful technique that is suitable for characterizing various aspects of RNA and small molecule in early stage of drug discovery. This presentation will overview the versatile roles of NMR spectroscopy in RNA drug discovery for providing the structural basis for the rational drug design. Advanced techniques for simplifying crowded spectra of large RNAs will be discussed. A disease-related RNA and small molecule structural study will be included as an example to elaborate how NMR techniques are employed to tackle challenges in drug discovery. We constantly want to improve our service for our customers. In answering the following question you help us to serve your needs even better in the future: What best describes your situation? I can unsubscribe at any time, by contacting Bruker or clicking on the opt-out link in the email if available. Tuesday, 30 January , CET. Watch On Demand. Martial Piotto Pharma product manager of Biologics solutions. Topic Input value is invalid. First name. Last name. Work Phone. Job Title. Are you already in contact with your Bruker representative regarding any product inquiries? Yes No Please choose an option. Investing: Buying within a year Learning: Expanding my knowledge Purchasing: Actively in the buying process Searching: Investigating a technology What best describes your situation. By submitting this form I agree my personal data will be used to process my registration to the webinar. Yes - I agree. Thank you. The invitation link has been resent.

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NMR Spectroscopy in RNA Drug Discovery

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