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Drug use is often associated with risky and unsafe behavior. However, the acute effects of cocaine and cannabis on performance monitoring processes have not been systematically investigated. The aim of the current study was to investigate how administration of these drugs alters performance monitoring processes, as reflected in the error-related negativity ERN , the error positivity Pe and post-error slowing. A double-blind placebo-controlled randomized three-way crossover design was used. Sixty-one subjects completed a Flanker task while EEG measures were obtained. Neither drug affected post-error slowing. These results demonstrate diametrically opposing effects on the early and late phases of performance monitoring of the two most commonly used illicit drugs of abuse. Conversely, the behavioral adaptation phase of performance monitoring remained unaltered by the drugs. N2 - Drug use is often associated with risky and unsafe behavior. AB - Drug use is often associated with risky and unsafe behavior. Opposite effects of cannabis and cocaine on performance monitoring. Section Psychopharmacology Psychopharmacology. Overview Fingerprint. Abstract Drug use is often associated with risky and unsafe behavior. Access to Document Fingerprint Dive into the research topics of 'Opposite effects of cannabis and cocaine on performance monitoring'. Together they form a unique fingerprint. View full fingerprint. European Neuropsychopharmacology , 26 7 , — In: European Neuropsychopharmacology. In: European Neuropsychopharmacology , Vol. Published by Elsevier B. European Neuropsychopharmacology.

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The aim of the current study was to investigate how administration of these drugs alters performance monitoring processes, as reflected in the error-related.

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