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Cocaine may make some people have bowel movements. However, it may not necessarily be the drug, cocaine hydrochloride, that affects the digestive system. It may be due to other ingredients. Street dealers lace cocaine with other additives and drugs that can make a person need to go to the bathroom. People ingesting cocaine by mouth may have digestive system side effects. Nausea, vomiting, and constipation are other digestive effects of cocaine. Side effects can be short or long term. Long-term digestive effects of cocaine, such as perforation or bleeding, can be dangerous and potentially life threatening. Cocaine comes from the leaves of the coca plant, native to South America. The addictive substance is an alkaloid called cocaine hydrochloride. Cocaine hydrochloride causes many different effects on the body. In the short term, cocaine does not affect bowel movements. However, some people may have nausea. The long-term effects of using cocaine depend on how a person takes the drug. For example, using cocaine by mouth can cause severe bowel decay from reduced blood flow to the intestines. However, people do not usually have diarrhea with bowel decay. People may use cocaine, not knowing exactly what is in it. Street dealers may lace pure cocaine powder with fillers. This allows them to stretch their drug supply and increase profits. It is unclear if cocaine or other substances in the drug make people need to use the bathroom. Some people claim that having a bowel movement after snorting cocaine may be a psychological effect from feeling nervous and excited. However, medical research does not back these reports. Many factors contribute to how cocaine affects the body. The method of use and contaminants in cocaine can influence these. People usually snort cocaine in a powder form or rub it on their gums. Others may inject it directly into a vein or smoke it. The effects of the drug can last 15—60 minutes. However, the duration depends on how a person takes cocaine and how much they use. Cocaine stimulates the central nervous system by increasing the levels of the chemical messenger dopamine. Cocaine also causes an intense feeling of happiness and energy. It can also cause other effects, such as:. The long-term effects of using cocaine depend on how a person uses the drug. For example, people who snort cocaine may develop long lasting loss of smell and frequent nosebleeds. People who smoke it may develop asthma and have a higher risk of lung infections. Effects on the digestive system can occur in people who use cocaine by mouth. People may experience immediate digestive effects due to the contaminants and additives in cocaine. People typically only experience the digestive effects of cocaine if they ingest it by mouth. Pure cocaine does not immediately affect the digestive system, but extended use can cause severe bowel decay. Severe bowel decay involves the death of the cells lining the wall of the intestine due to restricted blow flow. Some drug dealers lace the cocaine fillers and cutting agents to extend their supply and make greater profits. Cocaine may contain substances such as laxatives and caffeine, making some people need to go to the bathroom. Some additives, such as fentanyl , can also cause constipation. Dealers may use additives such as:. People may also unknowingly ingest other drugs when using cocaine, such as amphetamines. Differing purities and different mixtures with additives can result in unique effects. While some people may poop after using cocaine, it may not occur every time. Cocaine increases the oxygen demand on the heart muscle cells and restricts blood flow by constricting blood vessels. In addition, cocaine can also affect platelets, which are cells involved in blood clotting. Cocaine can cause platelet aggregation, which leads to blood clots. These effects can strain the heart muscle and may cause serious complications such as a heart attack. Over time, cocaine can also accelerate the thickening of the blood vessel walls or atherosclerosis. People can also develop an irregular heartbeat from using cocaine. While there are no treatments for cocaine misuse that have Food and Drug Administration FDA approval, some treatment options include:. People may need to use the bathroom after using cocaine, but the drug may not have the same effect on everyone. Cocaine often contains additives and other drugs that can cause side effects, such as needing to have a bowel movement. Anecdotally, some people report needing to go to the bathroom after taking cocaine, as it causes heightened emotions. The length of time cocaine stays in a person's system depends on frequency of use and dosage, as well as other factors. Learn more. Learn more here. Cocaine is one of the most addictive and harmful drugs. Find out what cocaine is, its effects, what makes it addictive, and the health risks. If a person uses cocaine regularly and suddenly stops, they may experience withdrawal symptoms. Learn more about cocaine withdrawal here. Cocaine is a stimulant drug that is highly addictive. If a person uses cocaine, it can have both long- and short-term effects on their brain. Medical News Today. News Latest News. Podcasts All 3 ways to slow down type 2 diabetes-related brain aging Toxic metals in tampons: Should you be worried? Can tattoos cause blood or skin cancer? What makes a diet truly heart-healthy? Is intermittent fasting actually bad for your heart? Newsletters Sign Up. Follow Us. Why does cocaine make you poop? Medically reviewed by Alan Carter, Pharm. How it causes pooping Effects on the body Effects on digestion Other factors Complications Getting help Summary Cocaine may make some people have bowel movements. Why does cocaine make a person poop? How cocaine affects the body. Effects on the digestive system. Cocaine misuse can also cause the following symptoms, which require immediate medical attention:. Other contributing factors. Signs of serious health complications. Getting help for cocaine misuse. How we reviewed this article: Sources. Medical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Share this article. Latest news Study detects early Alzheimer's 'stealth' phase before symptoms set in. Can standing too much be harmful to heart health? Semaglutide boosts heart health, weight loss but may lead to gut problems. Tenecteplase more likely to lead to 'excellent' stroke recovery, study finds. Mitochondria may trigger Crohn's disease by disrupting the gut microbiome. Related Coverage. Cocaine: How long does it stay in your system? Medically reviewed by Deborah Weatherspoon, Ph. How does cocaine affect the heart? Medically reviewed by Dr. Payal Kohli, M. Everything you need to know about cocaine. Medically reviewed by University of Illinois. Cocaine withdrawal explained. What are the effects of cocaine on the brain?

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Official websites use. Share sensitive information only on official, secure websites. An year-old Japanese man visited our hospital with abdominal fullness accompanied by lower abdominal pain. He presented with small bowel obstruction due to multiple diospyrobezoars. The bezoars were successfully removed without any surgical intervention by the administration of Coca-Cola Zero through a long intestinal tube and subsequent endoscopic manipulation. Such a combination may be the treatment of choice for small bowel obstruction due to bezoars. Keywords: multiple diospyrobezoars, small bowel obstruction, long intestinal tube, endoscopic manipulation, Coca-Cola Zero. Diospyrobezoars are defined as masses of hard, indigestible material that form in the gastrointestinal tract. While most bezoars are asymptomatic and are incidentally found in the stomach, cases of small bowel obstruction due to bezoars have been reported, in which the bezoars were surgically removed 1. In contrast, there have been few descriptions of non-surgical treatment for small bowel bezoars 2 , 3. We herein report a case of small intestinal obstruction caused by multiple diospyrobezoars, which were successfully removed by the administration of Coca-Cola Zero through a long intestinal tube followed by endoscopic manipulation. An year-old Japanese man presented to our hospital with abdominal fullness accompanied by nausea, vomiting, and lower abdominal pain. These symptoms had progressed during the three previous days. He was unable to consume either food or liquids during this period. He had been diagnosed with diabetes mellitus and was treated using glimepiride. However, the patient had no history of abdominal surgery. A physical examination revealed abdominal distension and tenderness without a palpable mass or rebound tenderness. The laboratory data revealed inflammation and dehydration. Abdominal computed tomography CT revealed dilatation of the small intestine, and a bubbly mass impaction in the stomach and the proximal ileum Fig. Subsequent small bowel radiography through a long intestinal tube revealed multiple filling defects in the ileum, which ranged from cm in size Fig. Detailed inquiries on his history revealed that he had been routinely ingesting a large number of persimmons every day. We therefore considered a diagnosis of diospyrobezoars resulting in small intestinal obstruction. A Plain and B Enhanced transverse section computed tomography CT images reveal distension of the small intestine and multiple bubbly mass impaction within the stomach arrow and ileum arrowheads. Small bowel radiography through a long intestinal tube detected multiple filling defects arrows in the ileum. A bezoar of the most distal side was considered to have caused the obstruction arrowhead because the water-soluble contrast material did not flow beyond it. In consideration of his age and general condition, we first attempted to dissolve the bezoars with Coca-Cola Zero Coca-Cola, Tokyo, Japan. He complained of abdominal distension; thus, after aspirating as much of the patient's bowel contents as possible, mL of Coca-Cola Zero was administered through the intestinal tube. Two hours later, a certain volume of the administered liquid was aspirated. This procedure was repeated twice daily for three days. The patient's blood glucose level remained within the normal range. Subsequent small bowel radiography and abdominal CT revealed that the bezoars had moved to the terminal ileum Fig. Furthermore, using colonoscopy, we were able to confirm that the green-to-brownish bezoars were impacting within the terminal ileum Fig. Since the bezoars were not stiff, we disintegrated them using a polypectomy snare. This enabled us to extract the bezoars from the cecum Fig. Consequently, four bezoars were successfully removed from the terminal ileum. After the procedure, the patient became asymptomatic without small intestinal dilatation. A Computed tomography CT reveal that the bezoars had moved to the terminal ileum. B Colonoscopy revealing that the ileocecal valve had become edematous. C Green-to-brownish bezoars were impacted within the terminal ileum. D The bezoars were extracted to the cecum. Subsequent esophagogastroduodenoscopy EGD revealed two firm bezoars remaining in the fornix to the upper gastric body and a gastric ulcer Fig. After four days, EGD revealed that the size of the bezoars remained unchanged. However, they had become friable, and we could easily disintegrate the bezoars using a polypectomy snare Fig. A Esophagogastroduodenoscopy revealing two green-to-brown bezoars at the fornix to the upper gastric body, B A gastric ulcer at the antrum, C After ingesting Coca-Cola Zero, D the bezoars disintegrated into small pieces. The analysis of the bezoars that had been removed from the stomach and terminal ileum by infrared absorption spectrometry showed that they were composed of tannin monomers, a component of persimmons, which confirmed our initial suspicion of diospyrobezoars. A diospyrobezoar is a specific type of phytobezoar that is caused by the excessive intake of persimmons and which is currently the most common type of bezoar in Asian countries 4 , 5. Diospyrobezoars are extremely hard; thus, it is difficult to fracture them endoscopically. In contrast, there have been some descriptions of the efficacy of Coca-Cola for the dissolution of bezoars 6 , 7. Lee et al. However, the same investigators also mentioned that Coca-Cola could decrease the size and stiffness of diospyrobezoars. Since the solubility of diospyrobezoars in Coca-Cola Zero and Coca-Cola is reported to be similar 8 , we used Coca-Cola Zero consideration of the patient's underlying diabetes mellitus 9. While a much larger volume of Coca-Cola is recommended for gastric bezoars 6 , there are no reports describing the recommended volume for the treatment of small bowel obstruction. We chose to administer mL through a long intestinal tube for two hours to avoid the development of abdominal pain and distension. The mechanism underlying the effect of dissolution therapy with Coca-Cola is still unknown. In addition, the fine CO 2 bubbles might permeate the microscopically uneven surface of the bezoars 8. Although the components of the bezoars obtained from the terminal ileum and stomach were consistent, the firmness at the time of the initial treatment was different. In other words, the bezoars of the terminal ileum were soft, while those of the stomach were stiff. After the patient consumed Coca-Cola Zero, the bezoars of the stomach become friable. This change suggests that the bezoars of the small intestine also became friable. Consequently, the bezoars successfully moved to the terminal ileum. Colonoscopy revealed that the ileocecal valve had become edematous. We hypothesized that this was caused by an impacted bezoar, which resulted in a blood circulation disorder. There have been few reports on the endoscopic treatment of small intestinal obstruction due to a single bezoar 2 , 3. In contrast, it has been reported that surgical intervention is inevitable for the treatment of small intestinal obstruction with multiple bezoars 1 , Certainly, there have been cases of immobile small bowel bezoars with impaction, massive bleeding, or perforation. Thus, we believe that conservative treatment using Coca-Cola coupled with endoscopic manipulation may be an appropriate choice for treating cases of small bowel bezoars. As a library, NLM provides access to scientific literature. Intern Med. Find articles by Kei Endo. Find articles by Keisuke Kakisaka. Find articles by Yuji Suzuki. Find articles by Takayuki Matsumoto. 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