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This is a HealthLine Online content page created by Healthwise. HealthLine Online helps you make better decisions about your health. Cocaine is a powerful stimulant. It is also called coke, snow, C, flake, or blow. It may be mixed cut with other substances, such as cornstarch, talcum powder, or sugar. It may also contain other drugs, such as fentanyl, procaine, or amphetamine. Small amounts of cocaine make a person feel euphoric, energetic, talkative, and mentally alert. It also decreases appetite and the need for sleep. Some people use cocaine and alcohol together, which can cause stronger, longer-lasting effects. When large amounts of cocaine are taken, the high is more intense. But large doses can cause strange or violent behaviour. For example, the person may have tremors or muscle twitches or become paranoid. After using cocaine, the person feels irritable, tired, and depressed. This is called a coke crash. If a person takes the drug at higher and higher doses a binge , they can get more and more irritable, restless, and paranoid. This can cause a person to hear or see things that aren't there hallucinations. Use of cocaine can lead to serious health problems. They include:. Sometimes sudden death can occur, even with the first use of cocaine. Sudden death from cocaine use may occur because of a heart attack or seizure in which breathing stops. Sudden death is more likely to occur when cocaine is used along with alcohol. The effects of cocaine last about 1 to 2 hours. Cocaine can be detected in a urine drug screen up to 6 days after it has been taken. Signs that a person may be using cocaine include:. Author: Ignite Healthwise, LLC Staff Clinical Review Board All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals. Clinical Review Board All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals. This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content. If you have questions about your health, dial on your phone or visit HealthLine Online. Home Your Health Cocaine. Top of the page. Overview Cocaine is a powerful stimulant. Two forms of cocaine are: The white powder form. It can be sniffed through the nose snorted or dissolved in water and injected in a vein intravenous, or I. It can also be taken by mouth or rubbed onto the gums. The rock crystal, or freebase, form. It can be smoked. Freebase cocaine is called crack, chips, chunks, or rocks. They include: Changes in heart rhythm and heart attack. Headache, seizure, and stroke. Loss of smell, persistent runny nose, nosebleeds, hoarseness, and destruction of the nasal separation nasal septum when the drug is snorted. Bowel tissue death. Damage to the kidneys. Serious infections, HIV, hepatitis , or allergic reactions when injected into a vein. Weight loss and poor nutrition from loss of appetite. Developing a stimulant use disorder. Signs of use Signs that a person may be using cocaine include: Having supplies for injecting cocaine. These are called an outfit or rig. It may include syringes, spoons with smoke stains, small pieces of glass, and razor blades. Persistent runny nose and nosebleeds, which may be a sign of snorting cocaine. Going long periods of time without sleeping or eating. Personality changes. Credits Current as of: November 15, Current as of: November 15, Help Information Emergency. If you believe you have an emergency, dial

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J, Biotechnology and Bioprocessing. Sage has been used for centuries as a sacred herb in Roman rituals to extend life, especially in china. The positive effects of the plant on health have been described frequently from the ancient Roman period until the middle ages. It is used for the treatment of bronchial infections, colds and cough. It is also traditionally used to relieve gastraintestinal symptoms such as dyspepsia, gas, indigestion, bloating. In the treatment of excessive sweating in menopause. It has been shown to be effective. Its effectiveness is used as a mouthwash in the irritation of the oral mucosa as well as in pharyngitis, tonsillitis, gingivitis, glossitis infections. These teas used in treatment are prepared as infusion, decoction and cold maceration. Approximately 20 g of dried plant material prepared for analysis. The sample is weighed. The weighed sample is placed in the glass clevenger flask. Approximately 10 times ml of pure water is added to the sample. It is subjected to hydrodistilation process for about 2 hours. Then the reading of the essential oil sample, which accumulates in the graduated part and creates a phase difference with water, is taken and the result is recorded in ml. Then, based on the weight, the amount of essential oil is calculated as a percentage. We think that the differences may be due to differences in geographical regions and precipitation. Ventilatory oil ratios have been shown in course studies that ontogenetic factors can also be affected by many factors. Sage has been used for centuries as a sacred herb in Roman rituals to extend life, especially in China. It is also traditionally used to relieve. Gastraintestinal symptoms such as dyspepsia, gas, indigestion, bloating. These teas used in treatment are prepared as infusion, decoction and cold maceration 1,2,3,4. In this study, we tried to determine the essential oil content of Salvia officinalis grown in Konya for The amount of essential oil is specified as the amount of substance defined as milliliters in g of anhydrous plant obtained by distillation under the conditions specified in this standard. The principle of this method is to distill the aqueous suspension of the sample, collect the distillate in a graduated tube with a certain volume of xylene used to hold the essential oil, wait for the separation of the organic and aqueous phases, read the total volume of the organic phase, and calculate the volatile oil after extracting the xylene volume. Samples were diluted 1: with hexane for analysis. Helium was used as carrier gas at a flow rate of 0. In line with this temperature program, the total analysis time was 30 minutes. Component percentages of the results were made using the FID detector, and the diagnosis of the components was made using the MS detector. Essential oils are the effective ingredients of most of the important medicinal and aromatic plants produced in the world 5. The ratio of essential oils, an important secondary metabolite for plants, varies depending on many factors. On the ratio of essential oils; The genotype of the plants used in production, the climate and soil characteristics of the region where the production is made and the cultivation techniques are effective 6. One of the most important cultivation techniques that affect the rate of essential oil is when the plants are harvested. Studies have shown that the proportion of essential oil that aromatic plants contain varies depending on the growth period of the plant 7,8,9. This is of great importance for manufacturers who want to produce standard quality products. Because even if all the production-related applications are fulfilled completely, the harvest at the wrong time affects the essential oil content of the product negatively. This decreases the market value of the product. In order to eliminate this negativity, it is necessary to determine the most appropriate harvest times of the aromatic plants to be produced according to the production regions. The parts of sage used as drugs are leaves Folia Salviae , flowers Flores Salviae and essential oil Oleum Salviae obtained from leaves and flowers, and the most important bioactive substance is the essential oil they contain While the rate of essential oil in the fresh leaves of the plant is around 0. In the codex, the essential oil ratio is required to be at least 1. The proportion and components of essential oils of medicinal and aromatic plants change under the influence of the environment, genetic factors, and aquaculture practices Likewise, the rate and composition of essential oils of aromatic plants differ depending on the developmental period of the plants. Considering this situation, when cultivating aromatic plants, it is of great importance to harvest the plants at the appropriate time in order to obtain the most essential oils and oils with the essential oil composition that are most suitable for the purpose of production. The leaf drop of Salvia officinalis is registered with the European Pharmacopoeia and has a positive monograph of the German E commission. It contains tujon. Salvia triloba leaf drogu is similar to salvia officinalis leaves in terms of chemical structure and treatment. Salvia triloba is used instead of medicinal sage since it does not grow naturally in Turkey. This strain, which contains traces of tujon, is also included in the European pharmacopoeia. The drug of both medicinal plants is accepted as medicinal sage in the scientific platform. This mixture is cytotoxic. The essential oil is 1. According to the European pharmacopoeia, the whole drug is required to contain at least 1. Essential oil is mainly composed of monoterpenes. It is desirable that it contains essential oil. Essential oil consists mainly of monoterpenes. It contains Effect and use The usage of Dalmatian sage and Turkish sage show the same properties. It is used in colds, tonsillitis, pharyngitis. When using the infusion should be careful not to be hot. It is used as a gargle every 2 hours. It has bactericidal effects as it is herbal relaxing. It has spectrum. The antibacterial effect of Dalmatian tea has been shown that carnosolic acid, which is a diterpene bitter substance, prevents replication by affecting the RNA synthesis in bacteria. Although this effect is also in Turkish sage, the study was made with Dalmatian sage and has an antibiotic effect. Sage, which also has antiviral properties, is especially used in vesiculobullous stomatitis of herpes simplex viruses. According to recent studies, it is known that topical anti-inflammatory effects are mostly caused by ursolic acid in inflammatory diseases of the mouth and throat area. It has antioxidant properties, it shows astringent properties thanks to its chlorogenic acid, ellaganic acid, epicatechin and epiglocatechingallate. The fields of use of Dalmatian sage, approved according to the German E commission, include dyspeptic diseases, feeling of fullness, mild gastrointestinal cramps, treatment of hyperhidrosis and mouth throat mucosa diseases. As approved by the commission E of Dalmatian sage, it has antiperspirant properties, not increasing perspiration, contrary to its traditional use. Infusion of 1 teaspoon of sage leaves with ml of hot water as a medicinal tea is prepared, kept for minutes with the top covered, and infused. The reason for the long duration of this period is to allow the bacteriostatic effective tannin compounds to pass into the water. In this way, it is accompanied by astringent effect; sips are drunk. This medicinal tea is also used as mouthwash for stomatitis and gingivitis. It is especially recommended for mouth and throat infections and herpes viruses. If it is used more than 15g daily dose, it may cause tachycardia, hot flushes, and dizziness, depending on its content. Dalmatian sage is contraindicated in epileptic patients during pregnancy and lactation due to the thujone it contains. It can only be used as mouthwash after the fourth month of pregnancy, not exceeding 2 times a day, and for a total of 4 weeks 4. The chemical compositions of essential oils of aromatic plants differ under the influence of the genotypes of the plants used in production, the ecological conditions of the production area and the cultivation practices. One of the factors affecting the change in essential oil composition is the plant growth period when the harvest is made. The ratio of essential oil components in plants varies greatly depending on the developmental period in which the harvest is made. This change is more noticeable in the main components that make up the essential oil. In this study, the main components of the essential oil of medicinal sage, alpha-thujone, camphor, bornyl acetate, germakrene, and 1. This situation can be explained by the effect of the environmental conditions changing depending on the growth stages of the plant on the physiological state biosynthesis path of the plant and the aging that occurs in the plant organs with the progression of the vegetation period 5, 9. Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. 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Abstract Sage has been used for centuries as a sacred herb in Roman rituals to extend life, especially in china. It contains The usage of Dalmatian sage and Turkish sage show the same properties. Saad B Said O eds commonly used herbal medicine in the mediterranean. World Medicine bookstore. Nobel Academic Publishing, Ankara. Botanica Serbica, 37 2 : Medical and Aromatic Plants Symposium Proceedings , Bayram E. Volume 10 , Issue 1, Pages 73 — 82 European Journal of Science and Technology. Scientia Horticulturae, 2 : View at Publisher View at Google Scholar. Mina Sherif Soliman Georgy. Anthony Kodzo-Grey Venyo. Gomez Barriga Maria Dolores. Maria Dolores Gomez Barriga. Dr Maria Dolores Gomez Barriga. Dr Maria Regina Penchyna Nieto.

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