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Mnemonic for the Hunter criteria for Serotonin Syndrome some of them are a bit iffy! In the very unwell call for help early and get the patient assessed in the appropriate place, such as resus. C — ECG in all symptomatic patients and repeat this if further concerns such as an initially abnormal trace or new symptoms. Fluid resuscitation if hypotensive. Echo may be needed in severe cases to assess the benefit of vasopressors and inotropes. D — Keep an eye on GCS which can change, check blood sugars and treat appropriately. Ensure you check pupil size and ankle clonus as well. Always check toxbase for treatment in these cases. Barbiturates are recommended second line after benzodiazepines to avoid phenytoin. E — Temperature, treat hyperthermia as a priority. This session considers the three main forms of drug related hyperthermia, malignant hyperthermia, neuroleptic malignant syndrome and serotonin syndrome. Great blog. Great pharmacology. You must be logged in to post a comment. Learning Content Type. Clinical Cases. Learning Sessions. Ear, nose and Throat. Environmental emergencies. Gastroenterology and hepatology. Infectious diseases. Mental Health. Musculoskeletal non-traumatic. Neonatal Emergencies. Oncological Emergencies. Palliative and end of life care. Pharmacology and poisoning. Sexual Health. Surgical emergencies. Other clinical presentations. Non- Clinical. Complex or challenging situations in the workplace. Lead the ED shift. Support, supervise and educate. Participate in and promote acitivity to impove quality and safety of paitent care. Manage, administer and lead. Sign up. All Courses. Member only content. Non members will be redirected to Homepage. Exam Info. SBA Revise. All SBA Revise. SBA Revise 1. SBA Revise 2. SBA Revise 3. SBA Revise 4. SBA Revise 5. SBA Explained. All SBA Explained. Exam Technique. Question Talk Through. Guidelines to Know. OSCE - coming soon. All TERN. About TERN. Current Projects - HED. Got a Research idea? Critical Appraisal. All Critical Appraisal. Critical Appraisal Dictionary. Relative Risk. Positive Values. Academic Careers. Getting Started in Research. Personal Journeys. Top 5 Papers. The Airways 2 Trial. Breaking Evidence. All Breaking Evidence. Non-Trainee Abstracts blog The Rod Little Prize shortlisted abstracts All EC Incubator. EC Incubator Sign-up. Interactive Symposium. Members Content. Shaping Your Future. Write a successful PHD Application. Contact Us. Contact Form. Content Types. Contributing and Feedback. CPD Diary. Induction FAQ. Clinical Case Template. Learning Session Template. SBA Template. Blog Template. Patient Image Consent Form. Privacy Policy. Data request. The Teams. What We Do. Our Mission. Site Structure. Search Search. Originally developed by Merck in , used in by the US Army in psychological warfare tests and in the s as a psychotropic drug to induce disinhibition marriage counselling! Causes release of Serotonin in the brain and some dopamine. Central and peripheral catecholamine release also occurs. Metabolised predominantly in the liver CYP , half-life hours, recreational effect hours, renally excreted. Onset of effect around 30 minutes from ingestion — peak effects at minutes. Pure MDMA is a white, crystalline powder. It is usually stamped into tablets of varying colours and logos extremely useful to ask about the colour and imprint on the tablet for public health surveillance and Police investigation when dealing with patients with ecstasy ingestion but is sold as a white powder. Both powder and pills are usually taken orally, occasionally smoked or snorted, and rarely injected. Pills usually contain mg MDMA higher quantities potentially dangerous, especially if paediatric patient or multiple doses ingested. Class A drug in the UK — illegal to possess, give away or sell. Possession can be punished with 7 years in jail, supplying can result in lifetime jail sentence and an unlimited fine. What is the scope of the problem in the UK? The office of national statistics puts ecstasy use in the year ending March at 1. In the 16 — 24 year old age group use of ecstasy was 2. We do have data that suggests the strength of both pill and powder forms of ecstacy have increased significantly over the last 20 years. Pills range from 3mg to mg. This includes several cathinones which can cause prolonged stimulation and an urge to re-dose quickly. How do these patients present? Related Posts. Drug Induced Hyperthermia This session considers the three main forms of drug related hyperthermia, malignant hyperthermia, neuroleptic malignant syndrome and serotonin syndrome. Drug Related Hyperthermia This session considers the three main forms of drug related hyperthermia, malignant hyperthermia, neuroleptic malignant syndrome and serotonin syndrome. August 12, at pm. Log in to Reply. Dr Syed Shahbaz Ahmer says:. July 10, at pm. Dr Angus James Bowman Perks says:. August 16, at pm. Leave a Reply Cancel reply You must be logged in to post a comment.

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