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Number of children. It lies at the foot of the imposing Sella and Col di Lana massifs. They consist mainly of carbonate rock and were formed in the Triassic period about million years ago by the accumulation of calcareous algae , shells and corals , raised to over 3, m above sea level by Alpine orogeny. They were discovered and studied between and by the French naturalist Deodat de Dolomieu. They were named Dolomites in his honour and are also called 'Pale Mountains' because of the colour of the rock. They first appeared in written sources in in a travelogue by the English naturalists Churchill and Gilbert. Despite the whiteness that distinguishes them from the surrounding rocks, the mineral of which they are composed has a high capacity to reflect light: hence the phenomenon of the 'Enrosadira'. At sunrise and sunset, when colours are more subdued, the rock absorbs them completely, making these vertical walls glow from pink to orange to fiery red , making sunrise and sunset a moment of total ecstasy. But there is also room for those who love peace, quiet and relax : Meadows, forests and pastures that are green in summer, white and snowy in winter and full of nuances in spring and autumn, allow you to completely disconnect from everyday city life and have a unique experience. The 'Setsass' massif consists of two ancient overlapping atolls : the 'Setsass' and the small 'Setsass'. Landmark for the history of geology, is one of the first areas studied in the Dolomites and is also called cliff 'Richthofen' ; the research carried out by this baron allowed to give substance to the theory of plate tectonics. This mountain is very important from a geological point of view because it preserves the geometry of two cliffs with fossil underwater ramps and the connection with the deep sea deposits that surrounded them, the formation of 'S. The most attractive activities start directly from the village. Experience the four seasons.

Volume 616 Issue 7957, 20 April 2023

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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Although currently there is no known threat to Earth from asteroids, strategies to protect the planet from a collision are being explored. A third paper reports observations from the Hubble Space Telescope of the material ejected during the collision. A fourth paper uses modelling to characterize the transfer of momentum that resulted from the impact. And the final paper reports on citizen science observations before, during and after the collision. Influential studies have helped regulators to spot problems at banks and step in before they spread. But, as the events of the past month show, stability must not be allowed to breed complacency. 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An embryo-like ball of cells offers a way to study pregnancy and its complications without the typical ethical dilemmas. Descriptions of lunar eclipses by monks and other scholars help scientists to pinpoint effects of ancient eruptions. The Environmental Protection Agency has released draft regulations that set the stage for a huge transition to electric vehicles. A raft of commercial lunar missions are taking off in The first lander is set to touch down this month, signalling a new era for Moon science and exploration. Perceptions have shifted dramatically in the past few years on the therapeutic value of illicit drugs such as ecstasy. But questions still linger about what FDA approval might look like. Depictions of fetuses have helped to teach safer birthing practices and saved lives — but they can also be used to erase the person giving birth. Multi-genome assemblies called pangenomes can capture genetic diversity in a species, but researchers are still working out how best to build and explore them. Scent sculptor Michael Moisseeff simulates all manner of aromas from the everyday and historical to the extraterrestrial. Assessing the genetic and cellular changes that underlie human lung cancer as it evolves could aid the development of treatments. A strategy for deflecting asteroids on a path towards Earth has passed its first test. The results confirm predictions about how asteroids respond to impact — and offer useful insights. The ability to separate the radioactive element americium from spent nuclear fuel would lower the long-term hazards of nuclear waste. An inorganic molecular cage that selectively binds to americium opens up a separation strategy. Genome sequencing, combined with methods for deducing how genomic regions interact, have now provided insight into how the wings that give skates and rays their characteristic shapes evolved more than million years ago. A protein from Epstein—Barr virus called EBNA1 has been shown to bind to and break human chromosome 11, producing instability in the genome that might cause a predisposition to cancer. The impact of the DART spacecraft on the asteroid Dimorphos is reported and reconstructed, demonstrating that kinetic impactor technology is a viable technique to potentially defend Earth from asteroids. The 33 minute change in the orbital period of Dimorphos after the DART kinetic impact suggests that ejecta contributed a substantial amount of momentum to the asteroid compared with the DART spacecraft alone. The authors report on a determination of the momentum transferred to an asteroid by kinetic impact, showing that the DART kinetic impact was highly effective in deflecting the asteroid Dimorphos. Optical observations of Dimorphos, a satellite of the asteroid Didymos, before, during and after the impact of the DART spacecraft, from a network of citizen science telescopes across the world are reported. By using millikelvin scanning tunnelling microscopy to study atomically flat terraces on U-terminated surfaces of the heavy-fermion superconductor URu 2 Si 2 , the two-dimensional heavy fermions are shown to form quantum-well states on the surface. A two-dimensional field-effect transistor made of indium selenide is shown to outperform state-of-the-art silicon-based transistors, operating at lower supply voltage and achieving record high transconductance and ballistic ratio. Methane can be oxidized to methanol using N -heterocyclic carbene-ligated Fe II complexes, in which the hydrophobic cavity captures the methane substrate from an aqueous solution and releases the hydrophilic methanol product back into the solution. A new strategy to separate radioactive americium from lanthanides based on complexation with polyoxometalates and ultrafiltration technique is highly efficient and rapid, does not involve any organic components and requires minimal energy input. A depolymerization method is described that uses electrified spatiotemporal heating to selectively generate monomers from the commodity plastics polypropylene and poly ethylene terephthalate , allowing control over the pyrolysis of plastic waste and reducing the formation of side products. Skate-specific changes in the epigenome and its three-dimensional organization contributed to the evolution of the batoid fin morphology. Epstein—Barr Virus EBV nuclear antigen 1 is shown to induce breakage of a fragile site on chromosome 11 by binding to a cluster of EBV-like imperfect palindromic repeats. Neurons in the central amygdala contribute to the reward prediction error responses of dopamine neurons to facilitate reward learning, but are not involved in aversive learning. The impact of artificial intelligence in cardiac function assessment is evaluated by a blinded, randomized non-inferiority trial of artificial intelligence versus sonographer initial assessment of the left ventricular ejection fraction. Analyses of multiregional tumour samples from patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome. A longitudinal evolutionary analysis of lung cancer patients with metastatic disease reveals the timing of metastatic divergence, modes of dissemination and the genomic events subject to selection during the metastatic transition. Computational and machine-learning approaches that integrate genomic and transcriptomic variation from paired primary and metastatic non-small cell lung cancer samples from the TRACERx cohort reveal the role of transcriptional events in tumour evolution. Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer. In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy. A proximity labelling-based approach for mapping nuclear protein—protein interactions is described that could advance epigenetic drug discovery. A computational approach is used to design modular proteins that bind to synthetic peptides and disordered regions of human proteins with high affinity and specificity. A structure—function analysis of cystic fibrosis transmembrane conductance regulator shows its two nucleotide-binding domains dimerize before channel opening, and reveals a mechanism through which conformational changes in the channel regulate chloride conductance. One of the most abundant base materials for bioplastics is cellulose, which is responsible for the structural rigidity of plant cell walls. Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily. Skip to main content Thank you for visiting nature. Crash course Although currently there is no known threat to Earth from asteroids, strategies to protect the planet from a collision are being explored. This Week. Strengthen links between science and high finance Influential studies have helped regulators to spot problems at banks and step in before they spread. Editorial 19 Apr Editorial 18 Apr Why open-source generative AI models are an ethical way forward for science Researchers should avoid the lure of proprietary models and develop transparent large language models to ensure reproducibility. World View 18 Apr Hair buried in a cave shows hallucinogen use in ancient Europe Ritually shorn strands suggest that people living some 3, years ago consumed plants with mind-altering properties. Research Highlight 11 Apr That new car smell has a whiff of health hazards Surface temperature drives emissions of chemicals that give a newly manufactured vehicle its signature aroma. Research Highlight 12 Apr Better than Chanel: perfumed male bees draw more mates A daub of floral scent gives male orchid bees a leg-up on fathering offspring. Sunshine is transformed into green hydrogen on an ambitious scale Prototype facility smashes record for converting solar power to hydrogen for its technology category. Research Highlight 13 Apr Lab-grown fat with texture like the real thing could enrich cultured meat Approach could make it easier to scale up production of cultivated meat. News 17 Apr Global scholars decry funding ban on influential Indian research centre International dismay after New Delhi-based Centre for Policy Research funding suspended. News 06 Apr How air pollution causes lung cancer — without harming DNA Studies in mice suggest that tumour growth is triggered by inflammation caused by tiny particles, rather than genetic mutations. News 05 Apr News 12 Apr Death threats, trolling and sexist abuse: climate scientists report online attacks Survey highlights experiences of dozens of climate researchers who have endured online harassment related to their work. Medieval accounts of eclipses shine light on massive volcanic eruptions Descriptions of lunar eclipses by monks and other scholars help scientists to pinpoint effects of ancient eruptions. US aims for electric-car revolution — will it work? News Explainer 12 Apr Private companies are flocking to the Moon — what does that mean for science? News Feature 18 Apr US could soon approve MDMA therapy — opening an era of psychedelic medicine Perceptions have shifted dramatically in the past few years on the therapeutic value of illicit drugs such as ecstasy. News Feature 19 Apr How sketches of the womb have empowered and oppressed women over the ages Depictions of fetuses have helped to teach safer birthing practices and saved lives — but they can also be used to erase the person giving birth. Book Review 17 Apr Justice over environmental murders, and how relationships boost happiness: Books in brief Andrew Robinson reviews five of the best science picks. Book Review 06 Mar Correspondence 18 Apr Stat checkers: make reproducible computer code mandatory Dominic Guitard Sylvain Fiset. Rethink changing species names that honour real people Guilherme S. Leaving academia for industry? Collections: Careers advice from scientists in industry Hiring in science. Career Feature 17 Apr Every base everywhere all at once: pangenomics comes of age Multi-genome assemblies called pangenomes can capture genetic diversity in a species, but researchers are still working out how best to build and explore them. Technology Feature 18 Apr Recreating the fragrance of the Moon in a lab Scent sculptor Michael Moisseeff simulates all manner of aromas from the everyday and historical to the extraterrestrial. Where I Work 17 Apr Molecular portraits of lung cancer evolution Assessing the genetic and cellular changes that underlie human lung cancer as it evolves could aid the development of treatments. Metal-oxide cages open up strategy for processing nuclear waste The ability to separate the radioactive element americium from spent nuclear fuel would lower the long-term hazards of nuclear waste. Genome reveals how the skate got its wings Genome sequencing, combined with methods for deducing how genomic regions interact, have now provided insight into how the wings that give skates and rays their characteristic shapes evolved more than million years ago. Epstein—Barr virus is an agent of genomic instability A protein from Epstein—Barr virus called EBNA1 has been shown to bind to and break human chromosome 11, producing instability in the genome that might cause a predisposition to cancer. Successful kinetic impact into an asteroid for planetary defence The impact of the DART spacecraft on the asteroid Dimorphos is reported and reconstructed, demonstrating that kinetic impactor technology is a viable technique to potentially defend Earth from asteroids. Article Open Access 01 Mar Orbital period change of Dimorphos due to the DART kinetic impact The 33 minute change in the orbital period of Dimorphos after the DART kinetic impact suggests that ejecta contributed a substantial amount of momentum to the asteroid compared with the DART spacecraft alone. Momentum transfer from the DART mission kinetic impact on asteroid Dimorphos The authors report on a determination of the momentum transferred to an asteroid by kinetic impact, showing that the DART kinetic impact was highly effective in deflecting the asteroid Dimorphos. Light curves and colours of the ejecta from Dimorphos after the DART impact Optical observations of Dimorphos, a satellite of the asteroid Didymos, before, during and after the impact of the DART spacecraft, from a network of citizen science telescopes across the world are reported. Quantum-well states at the surface of a heavy-fermion superconductor By using millikelvin scanning tunnelling microscopy to study atomically flat terraces on U-terminated surfaces of the heavy-fermion superconductor URu 2 Si 2 , the two-dimensional heavy fermions are shown to form quantum-well states on the surface. Article Open Access 22 Mar Ballistic two-dimensional InSe transistors A two-dimensional field-effect transistor made of indium selenide is shown to outperform state-of-the-art silicon-based transistors, operating at lower supply voltage and achieving record high transconductance and ballistic ratio. Article 22 Mar Selective methane oxidation by molecular iron catalysts in aqueous medium Methane can be oxidized to methanol using N -heterocyclic carbene-ligated Fe II complexes, in which the hydrophobic cavity captures the methane substrate from an aqueous solution and releases the hydrophilic methanol product back into the solution. Article 05 Apr Ultrafiltration separation of Am VI -polyoxometalate from lanthanides A new strategy to separate radioactive americium from lanthanides based on complexation with polyoxometalates and ultrafiltration technique is highly efficient and rapid, does not involve any organic components and requires minimal energy input. Article Open Access 19 Apr Depolymerization of plastics by means of electrified spatiotemporal heating A depolymerization method is described that uses electrified spatiotemporal heating to selectively generate monomers from the commodity plastics polypropylene and poly ethylene terephthalate , allowing control over the pyrolysis of plastic waste and reducing the formation of side products. Collection: Chemical Engineering Distilled. Article 19 Apr The little skate genome and the evolutionary emergence of wing-like fins Skate-specific changes in the epigenome and its three-dimensional organization contributed to the evolution of the batoid fin morphology. Article Open Access 12 Apr Article 12 Apr Plastic and stimulus-specific coding of salient events in the central amygdala Neurons in the central amygdala contribute to the reward prediction error responses of dopamine neurons to facilitate reward learning, but are not involved in aversive learning. Blinded, randomized trial of sonographer versus AI cardiac function assessment The impact of artificial intelligence in cardiac function assessment is evaluated by a blinded, randomized non-inferiority trial of artificial intelligence versus sonographer initial assessment of the left ventricular ejection fraction. Article Open Access 05 Apr The evolution of lung cancer and impact of subclonal selection in TRACERx Analyses of multiregional tumour samples from patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome. The evolution of non-small cell lung cancer metastases in TRACERx A longitudinal evolutionary analysis of lung cancer patients with metastatic disease reveals the timing of metastatic divergence, modes of dissemination and the genomic events subject to selection during the metastatic transition. Genomic—transcriptomic evolution in lung cancer and metastasis Computational and machine-learning approaches that integrate genomic and transcriptomic variation from paired primary and metastatic non-small cell lung cancer samples from the TRACERx cohort reveal the role of transcriptional events in tumour evolution. Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer. Article 13 Apr Antibodies against endogenous retroviruses promote lung cancer immunotherapy In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy. Tracking chromatin state changes using nanoscale photo-proximity labelling A proximity labelling-based approach for mapping nuclear protein—protein interactions is described that could advance epigenetic drug discovery. De novo design of modular peptide-binding proteins by superhelical matching A computational approach is used to design modular proteins that bind to synthetic peptides and disordered regions of human proteins with high affinity and specificity. Article Open Access 29 Mar Article 29 Mar CFTR function, pathology and pharmacology at single-molecule resolution A structure—function analysis of cystic fibrosis transmembrane conductance regulator shows its two nucleotide-binding domains dimerize before channel opening, and reveals a mechanism through which conformational changes in the channel regulate chloride conductance. Matters Arising 19 Apr Focal Point on Bioplastics in Japan One of the most abundant base materials for bioplastics is cellulose, which is responsible for the structural rigidity of plant cell walls. Focal Point 26 Apr Close banner Close. Email address Sign up. Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing. Search Search articles by subject, keyword or author. Show results from All journals This journal. Advanced search.

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