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Learn about the medical, dental, pharmacy, behavioral, and voluntary benefits your employer may offer. Ecstasy MDMA is both a stimulant amphetamine-like and mild calming tranquilizing substance. Ecstasy pills often have a logo, such as cartoon characters, stamped on them. This drug is most often taken as a pill, but the powder form is sometimes snorted or, rarely, injected into a vein. This stimulant's effects help a person dance for long periods of time without getting tired. Ecstasy is said to enhance the sense of pleasure and boost self-confidence. Its hallucinogenic effects include feelings of peacefulness, acceptance, and empathy. People who use the drug claim they experience feelings of closeness with other people and want to touch or hug others. Ecstasy causes muscle tension and jaw-clenching, which has led to the use of baby pacifiers to reduce this discomfort. It also causes nausea, blurred vision, rapid eye movement, faintness, and chills or sweating. In high doses ecstasy can cause a sharp increase in body temperature, leading to dehydration, muscle breakdown, kidney failure, or heart failure and death. A person who does not drink fluids can become severely dehydrated. When ecstasy is used with alcohol, the effects can be more harmful. Ecstasy can cause confusion, depression, sleep problems, and severe anxiety that may last weeks after taking the drug. Over time, use of ecstasy can lead to thought and memory problems. If a rash that looks like acne develops after using ecstasy, the person may be at risk for liver damage by continuing use of the drug. Ecstasy usually does not last in a person's system longer than 12 to 16 hours. And many general drug screening tests do not detect it unless it is specifically targeted. Author: Healthwise Staff. This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content. To learn more about Healthwise, visit Healthwise. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. All rights reserved. All insurance policies and group benefit plans contain exclusions and limitations. For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. This website is not intended for residents of New Mexico. Selecting these links will take you away from Cigna. Cigna may not control the content or links of non-Cigna websites. Special Enrollment See all topics Looking for Medicare coverage? Shop for Medicare plans. Member Guide. Find a Doctor. Signs of use Sleep problems Skin rash similar to acne Possession of pills stamped with cartoon or other characters or possession of a powdered substance Personality changes Lifestyle changes, such as staying out all night at parties. Current as of: March 22, Page Footer I want to

MDMA ('Ecstasy') drug profile

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These datasets underpin the analysis presented in the agency's work. Most data may be viewed interactively on screen and downloaded in Excel format. All countries. Topics A-Z. The content in this section is aimed at anyone involved in planning, implementing or making decisions about health and social responses. Best practice. We have developed a systemic approach that brings together the human networks, processes and scientific tools necessary for collecting, analysing and reporting on the many aspects of the European drugs phenomenon. Explore our wide range of publications, videos and infographics on the drugs problem and how Europe is responding to it. All publications. More events. More news. We are your source of drug-related expertise in Europe. We prepare and share independent, scientifically validated knowledge, alerts and recommendations. About the EUDA. MDMA is a synthetic substance commonly known as ecstasy , although the latter term has now been generalised to cover a wide range of other substances. Originally developed in by the Merck chemical company, it was never marketed as such. Although proposed as an aid to psychiatric counselling, therapeutic use is extremely limited. It acts as a central nervous system CNS stimulant and has a weak hallucinogenic property more accurately described as increased sensory awareness. MDMA is under international control. MDMA is an abbreviation for m ethylene d ioxy- m ethyl a mphetamine. MDMA is a member of the larger group of ring-substituted phenethylamines. As with other phenethylamines, and like its close relative methamphetamine , MDMA also exists in two enantiomeric forms R and S. The most common salt is the hydrochloride CAS which occurs as a white or off-white powder or as crystals soluble in water. The phosphate salt is also encountered. Illicit products are seen principally as white tablets with a characteristic impression logo , less commonly as white powders or capsules. MDMA base is a colourless oil insoluble in water. Whereas phenethylamines without ring substitution usually behave as stimulants, ring substitution as in MDMA leads to a modification in the pharmacological properties. Ingestion of MDMA causes euphoria, increased sensory awareness and mild central stimulation. It is less hallucinogenic than its lower homologue , methylenedioxyamphetamine MDA. The terms empathogenic and entactogenic have been coined to describe the socialising effects of MDMA. Following ingestion, most of the dose of MDMA is excreted in the urine unchanged. Major metabolites are 3,4-methylenedioxyamphetamine MDA and O -demethylated compounds. Following a dose of 75 mg, the maximum plasma concentration of around 0. The plasma half-life is 6—7 hours. In animals, MDMA causes neurotoxicity, as evidenced by anatomical changes in axon structure and a persisting reduction in brain serotonin levels. The significance of these findings to human users is still unclear, although cognitive impairment is associated with MDMA use. Some of the pharmacodynamic and toxic effects of MDMA vary, depending on which enantiomer is used. However, almost all illicit MDMA exists as a racemic mixture. Fatalities following a dose of mg have been noted, but toxicity depends on many factors, including individual susceptibility and the circumstances in which MDMA is used. There are four principal precursors which can be used in the manufacture of MDMA and related drugs: safrole, isosafrole, piperonal and 3,4-methylenedioxyphenylpropanone PMK. Safrole is the key starting material in so far as the other three can be synthesised from it. In the original Merck patent of , safrole was reacted with hydrobromic acid to form bromosafrole, which was converted to MDMA using methylamine. Many illicit syntheses start with PMK and use either the Leuckart route or various reductive aminations including the aluminium foil method. All of these methods produce racemic MDMA. MDMA in tablet form is almost always used orally ingested , but the powdered form could also be snorted, inhaled or injected, although the latter route is rarely observed in the context of recreational ecstasy use. As some of the above names suggest, MDMA is a derivative of amphetamine and a member of the phenethylamine family. A number of homologous compounds with broadly similar effects, e. These and many other more distant relatives of MDMA have now been subsumed by the generic term ecstasy. Mitsubishis, Love Doves and many others. Using gas chromatography, the limits of detection in plasma and urine are 1. Iversen, L. King, L. Moffat, A. United Nations , Recommended Methods for the Identification and analysis of amphetamine, methamphetamine and their ring-substituted analogues in seized materials revised and updated , Manual for Use by National Drug Testing Laboratories , United Nations, New York. Homepage Quick links Quick links. GO Results hosted on duckduckgo. Main navigation Data Open related submenu Data. Latest data Prevalence of drug use Drug-induced deaths Infectious diseases Problem drug use Treatment demand Seizures of drugs Price, purity and potency. Drug use and prison Drug law offences Health and social responses Drug checking Hospital emergencies data Syringe residues data Wastewater analysis Data catalogue. Selected topics Alternatives to coercive sanctions Cannabis Cannabis policy Cocaine Darknet markets Drug checking Drug consumption facilities Drug markets Drug-related deaths Drug-related infectious diseases. Recently published Findings from a scoping literature…. Penalties at a glance. 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