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My account. Register account. Add to cart. Configure art print. Available as an art print on canvas, photo paper, watercolor board, uncoated paper or Japanese paper. Width Motive, cm. Additional border. Color of the border. Canvas Leonardo satin Canvas Venezia. Canvas Salvador matte Canvas Florenz. Watercolor Cardboard Renoir Museum Watercolor Kozo White, g Mulberry fiber paper, white. Kozo Natural, g Mulberry fiber paper, natural. Inbe White, g Mulberry bark and hemp, white. Unryu, 55g Washi with cloudy kozo fibers. Bamboo, g Smooth bamboo washi. Premio Unryu, g Washi with cloudy kozo fibers. Murakumo Natural, 42g Thin Japanese paper, natural. Bizan Natural, g Handmade washi, natural. Bizan White, g Handmade washi, white. Aluminum composite Aluminum with a polyethylene core. Acrylic glass Waterproof methyl metacreylate. Level of detail. Low details Normal details A lot of details. Canvas frame. No canvas frame. No lamination. Glass including back board. Picture hanger. No picture hanger. No spacer. Produktionszeit: Werktage. Should you desire adjustments to brightness and color, or a custom crop of the motif, we are happy to make these changes at no additional cost to you. Please do not hesitate to contact us. Excerpt from our top sellers. What our customers think about us 4. Anonym ProvenExpert. July 30, Gute Beratung, hochwertiger Druck, prima Verpackung, rasche Lieferung! Meisterdrucke kann ich sehr empfehlen. Michael ProvenExpert. May 17, Monnet dont j'avais vu l'original dans une exposition. January 10, Marc ProvenExpert. September 14, Sono molto soddisfatto dell'acquisto che ha rispettato le mie migliori aspettative. March 28, Ist insgesamt noch akzeptabel, aber wir sind nicht ganz zufrieden. April 17, Auch die freie Wahl des Formates hat mir gefallen. March 19, I ordered a print of a Soutine painting on photo paper and with a 3 cm border. I received an excellent print. I will order from Meisterdrucke in the future and will recommend others to use this company. Jes ProvenExpert. April 3, Genial, dass hier wirklich noch Leute mitdenken! Ich bin restlos zufrieden und werde sicher wieder bei Meisterdrucke bestellen. Danke, danke, danke! March 24, Gratulation Meisterdruckleute! Peter ProvenExpert. March 7, We have ordered a print of a painting we have been looking for for many years. The first print that arrived was a bit too dark, Meisterdrucke sent us a new one, without charge. The communication with Julia was very pleasant and we are very happy with the result. We can recommend Meisterdrucke from the bottom of our heart. Ellen from Ho January 14, Auch die Beratung war sehr professionell. Habe schon meine zweite Bestellung abgegeben und weitere werden sicher folgen. Walter ProvenExpert. March 26, Frequently Asked Questions about Meisterdrucke How does personalization work? Personalizing your art print at Meisterdrucke is a simple and intuitive process that allows you to design an artwork exactly to your specifications: Choose a frame, determine the image size, decide on a printing medium, and add suitable glazing or a stretcher frame. We also offer customization options such as mats, fillets, and spacers. Our customer service is available to help you design your perfect artwork. How can I tell if the picture fits in my room? At Meisterdrucke, you have the fascinating option to visualize the artwork you configured directly in your own space. For a tailored preview, simply upload a photo of your room and let the artwork appear on it. If you visit us via a mobile device, be it a phone or tablet, our augmented reality feature brings the image to life and seamlessly projects it into your space. An experience that uniquely combines art and technology. How do I choose the right medium? Choosing the medium is often a matter of personal taste. To give you a clearer idea, we have provided some images for each medium. For a holistic experience, we also offer you a sample set of all paper variants so you can make a decision not just visually but also haptically. You can take advantage of the sample set free of charge — only the shipping costs will apply. You can order the sample set directly. I'm not sure if I have configured my picture correctly! Do not worry. At Meisterdrucke, we do not proceed mechanically. We manually review each order. If there are any inconsistencies or peculiarities in the configuration, we will immediately contact you. Of course, our courteous and patient support is always at your side to assist you with the configuration. Together with you, we adjust your image by phone or email so that the final result exactly meets your expectations. Do you have any questions? Are you interested in an art print from our manufactory but still unsure? Do you need advice on choosing the medium or help with the order? Our experts are happy to assist you. Add to cart Configure art print. Height Motive, cm.

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A single neurotoxic dose of MDMA increases kynurenine pathway metabolism in plasma and hippocampus of rat. Tryptophan is converted into the first stable molecule of the pathway, kynurenine, through the action of the enzymes tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase. The pathway is divided into two branches, one of which forms kynurenic acid by means of kynurenine aminotransferases, and the other of which, by the action of kynurenine mono-oxygenase, gives rise to 3-hydroxykynurenine, a precursor of the neurotoxin quinolinic acid. Kynurenine, kynurenic acid and quinolinic acid have been implicated in various neurological and neurodegenerative disorders \[1\]. Objective : The aim of this study was to evaluate possible changes in the levels of major kynurenine pathway metabolites following MDMA administration. Plasma and hippocampal concentrations of serotonin, tryptophan, kynurenine and kynurenic acid were measured by high pressure liquid chromatography. Results: MDMA increases hippocampal concentrations of tryptophan 1 h and 3 h after administration, returning to control concentrations at 6 h. No differences in plasma concentrations of tryptophan occur at any of the times measured compared with the control group. Kynurenine concentrations are also raised in hippocampus 1 h, 3 h and 6 h after MDMA as are the plasma concentrations 3 h and 6 h after drug administration. MDMA raises kynurenic acid concentrations at 6 h in hippocampus and at 3 h in plasma. Serotonin concentrations decrease in hippocampus at all the time-points evaluated, and in plasma at 3 h and 6 h. Chen Y, and Guillemin GJ Kynurenine pathway metabolites in humans: disease and healthy states. International Journal of Tryptophan Research 2: Methylenedioxyamphetamine MDA and methylenedioxymethamphetamine MDMA cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity. The Journal of Neuroscience 8: Journal of Neurochemistry. ISSN electronic journal. Some rights reserved. Currently you have JavaScript disabled. In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page. Click here for instructions on how to enable JavaScript in your browser.

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