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When under the influence of this drug, the user feels neither fatigue nor thirst and becomes unresponsive to the alarm bells sent by the body. Toxic effects likely to occur in users who are particularly sensitive or as a result of abuse or prolonged used:. Tolerance to MDMA appears to develop quickly. That said, with repeated use, it becomes difficult, if not impossible for users to experience the same effects they did when they first started. Although some users become dependent, very few cases of MDMA-specific dependence have been reported in the literature. Since most users take this drug only occasionally, dependence is not very prominent. Withdrawal symptoms are caused by a depletion of serotonin and may include depression and anxiety. Other symptoms associated with withdrawal are insomnia, panic attacks, agitation, psychosis and paranoid delusions. During withdrawal, users may also experience fatigue, sadness, bad moods and nightmares. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment. Classification CNS disruptor stimulant and hallucinogenic effect : Agent that causes users to see, hear or feel things that do not exist, while stimulating mental functions and increasing the brain's overall alertness. The emotional and pro social effects of MDMA are likely caused by the release of large amounts of serotonin. Serotonin then triggers the release of the hormones ocytocin and vasopressin, which play an important role in love, trust, sexual arousal and other social experiences. This may explain the feeling of empathy and the increased need for intimacy associated with this drug. Routes of administration Ingested the most common route , smoked, injected or snorted. Effects sought out by the user Desire to communicate with others Distorted perception of time Euphoria Extraversion Heightened sensuality and increased need for intimacy Heightening and distortion of sensory and enjoyment perceptions Intensification of emotions Lowered inhibitions Reduced fatigue Self-confidence Spontaneity. Anxiety and insomnia Back ache, muscle pain and tension Confusion Defensive attitude Dehydration Depressive state when coming down from the high Dilated pupils Disorientation Dry mouth Exhaustion Flushing and excessive sweating Headache Impulsivity Increased heart rate Irrational behaviour Jaw tension Loss of appetite Loss of motivation Mental fatigue Motor tics, gait disturbance Nystagmus involuntary, jerky eye movements and blurred vision Obsessive behaviour Sexual dysfunction: erectile dysfunction; may prevent women from reaching orgasm Tachycardia increased heart rate Teeth grinding Trismus masticatory muscle spasm Urinary retention or urgent need to urinate. Anxiety and persistent fear Hallucination flashbacks Kidney and liver disorders Loss of appetite or decreased appetite and weight loss Major depressive disorder and suicidal thoughts Memory deficits and altered cognitive functions Outbursts of rage Sleep disorder. Corneal erosion Feelings of unreality Hypertonicity and incontinence Nausea and vomiting Panic attacks, suicidal thoughts Paranoid disorder. Many different street drugs are sold under the same name. Furthermore, nothing guarantees the quantity, purity or even the content of a street drug in spite of the fact that it may, in some cases, look like medication. Share This Article. Find a Pharmacy. Newsletter Signup. Expect up-to-date health and lifestyle advice, special promotions, and more! CNS disruptor stimulant and hallucinogenic effect : Agent that causes users to see, hear or feel things that do not exist, while stimulating mental functions and increasing the brain's overall alertness. Blocks the reuptake and promotes the release of serotonin, dopamine and noradrenaline.
Ecstasy (MDMA)
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The chemical name for ecstasy is 3,4-methylenedioxymethamphetamine, or MDMA. The chemical structure and the effects of MDMA are similar to amphetamine a stimulant and to mescaline a hallucinogen. Some of the other drugs include caffeine , ephedrine, amphetamine , dextromethorphan, ketamine , and LSD. Ecstasy sometimes contains highly toxic drugs, such as paramethoxyamphetamine PMA , which can be lethal even in low doses. MDMA was patented in and has been used experimentally, most notably as a supplement to psychotherapy in the s. Ecstasy is made in illegal labs with chemicals and processes that vary from lab to lab. Ecstasy is usually sold as a tablet or capsule that is swallowed. It may also be sold in powder form, or the tablets may be crushed and then snorted. There are also rare reports of the drug being injected. Ecstasy tablets come in different shapes, sizes and colours, and are often stamped with a logo, such as a butterfly or clover, giving them a candy-like look. Tablets that are sold as ecstasy may not contain MDMA. The increased use of ecstasy as a recreational drug began in the s in the United States. Young people at raves all-night dance parties were the group most commonly associated with ecstasy use. While still used by young people in clubs and at parties, ecstasy is now also used by a wider range of people in a variety of settings. A survey of Ontario students in grades 7 to 12 reported a decline in past-year use of ecstasy from six per cent in to 3. In low to moderate doses, ecstasy can produce feelings of pleasure and well-being, increased sociability and closeness with others. Like all stimulant drugs, ecstasy can make users feel full of energy and confidence. Even at low doses, ecstasy can also have strong negative effects. Higher doses are unlikely to enhance the desirable effects, and may intensify the negative effects. These effects include grinding of teeth and jaw pain, sweating, increased blood pressure and heart rate, anxiety or panic attacks, blurred vision, nausea, vomiting and convulsions. After the initial effects of the drug have worn off, users may also experience after-effects such as confusion, irritability, anxiety, paranoia, depression, memory impairment or sleep problems. The effects of ecstasy usually begin within an hour, and may last four to six hours. The duration of the after-effects cannot be predicted as precisely, though they may last for days or weeks. Signs of addiction include strong cravings for the effects of the drug, taking more of the drug than intended, and continuing to use the drug despite the problems it may cause. Tolerance to ecstasy builds up very quickly. This means the more often you take ecstasy, the less effect the drug has. There is little evidence to indicate that MDMA can produce physical dependence or withdrawal symptoms. It can be. Although some people regard ecstasy as a relatively safe drug, a growing number of deaths have been associated with it. As with many illegal drugs, these risks increase with the amount taken and frequency of use. A major factor in many ecstasy-related deaths is the dehydration and overheating that can result when ecstasy is taken in conjunction with all-night dancing. Ecstasy increases body temperature, blood pressure and heart rate, which can lead to kidney or heart failure, strokes and seizures. Ecstasy may cause jaundice and liver damage. People with high blood pressure, heart or liver problems, diabetes, epilepsy or any mental disorder are the most vulnerable to the potential dangers of ecstasy. Part of the danger is that people may not be aware that they have these conditions, and the effects of ecstasy can trigger symptoms. As with all illegal street drugs, the purity and strength of ecstasy can never be accurately gauged. Combining ecstasy with other drugs, whether illegal or prescription, may cause a toxic interaction. Several prescription medications are known to interact with ecstasy, including a type of antidepressant called monoamine oxidase inhibitors MAOIs and ritonavir, a protease inhibitor used to treat HIV. Driving or operating machinery while under the influence of ecstasy, or any drug, increases the risk of physical injury to the user and others. Animal research has established that ecstasy use can damage the brain cells that release serotonin. Research on humans is limited, but there is some evidence to suggest that ecstasy can damage the cells and chemistry of the human brain, affecting functions such as learning and memory. The risk of damage caused by ecstasy use may be linked to the amount taken and the frequency of use. However, some research suggests that even occasional use of small amounts of ecstasy may damage the brain cells that release serotonin, and that these effects may be long lasting. It is not known whether these effects may be permanent. A free tutorial on addictions is available on the Mental Health page. Back to top. Keep your finger on our pulse — latest CAMH news, discoveries and ways to get involved delivered to your inbox. To unsubscribe at any time click the link in our mailing or email: unsubscribe camh. Where does it come from? What does it look like? Who uses it? How does it make you feel? How long does the feeling last? Is it addictive? Is it dangerous? What are the long-term effects of using it? Can we count on your support? Donate to improve mental health care for everyone. Please select a newsletter. Please complete the following:. CAMH Foundation - provides updates on the mental health movement and ways you can get involved. First Name Please input a first name. 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