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Important: most of our location have visiting hours that you can attend without having an appointment. For some locations, you need to have an appointment beforehand. Pease check carfully what is needed for your location. On the map below you can find the locations and opening times of the DIMS facilities. Note that most of the information on the map is in Dutch, please use a translator if anything is unclear to you. Skip to content Testlocations. What are the rules? Which drugs? Where can I test? Testlocations Extra dangerous drugs. Start typing and press enter to search Zoek …. Close Vergroot lettertype. Clear cookies. Accessibility by WAH. Scroll to Top.
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MDMA 3,4-methylenedioxymethamphetamine or 'ecstasy' is a recreationally used drug with remarkable and characteristic prosocial effects. In spite of abundant attention in the scientific literature, the mechanism of its prosocial effects has not been elucidated in humans. Recently, research in animals has suggested that the neuropeptide oxytocin may induce these effects. In a double blind, randomized, crossover, and placebo-controlled study in 15 healthy volunteers we assessed blood oxytocin and MDMA concentrations and subjective prosocial effects after oral administration of mg MDMA or placebo. MDMA induced a robust increase of blood oxytocin concentrations and an increase of subjective prosocial feelings. Within subjects, the variations in these feelings were significantly and positively correlated with variation in oxytocin levels, and the correlations between these feelings and oxytocin were significantly stronger than those between these feelings and blood MDMA levels. MDMA induces oxytocin release in humans, which may be involved in the characteristic prosocial effects of ecstasy. Abstract MDMA 3,4-methylenedioxymethamphetamine or 'ecstasy' is a recreationally used drug with remarkable and characteristic prosocial effects. Substances Hallucinogens Oxytocin N-Methyl-3,4-methylenedioxyamphetamine.
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Acute neuropsychological effects of MDMA and ethanol (co-)administration in healthy volunteers
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