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At a party not long ago in Park Slope, Brooklyn, Kaitlin, a year-old senior at Columbia University, was recalling the first time she was offered a drug called Molly, at the elegant Brooklyn home of a cultural figure she admired. At one point, the hostess pulled Kaitlin aside and asked if she had ever tried the drug, which is said to be pure MDMA, the ingredient typically combined with other substances in Ecstasy pills. Since that first experience, Kaitlin has encountered Molly at a birthday celebration and at a dance party in Williamsburg. You just get very turned on — not even sexually, but you just feel really upbeat and want to dance or whatever. Molly is not new, exactly. MDMA, or 3,4-methylenedioxy-N-methylamphetamine, was patented by Merck pharmaceuticals in and did not make much news until the s, when psychotherapists began giving it to patients to get them to open up. Known for inducing feelings of euphoria, closeness and diminished anxiety, Ecstasy was quickly embraced by Wall Street traders and Chelsea gallerinas. Then, sometime in the last decade, it returned to clubs as Molly, a powder or crystalline form of MDMA that implied greater purity and safety: Ecstasy re-branded as a gentler, more approachable drug. And thanks in part to that new friendly moniker, MDMA has found a new following in a generation of conscientious professionals who have never been to a rave and who are known for making careful choices in regard to their food, coffee and clothing. Glatter used to go months without hearing about Molly; now, he sees about four patients a month exhibiting its common side effects, which include teeth grinding, dehydration, anxiety, insomnia, fever and loss of appetite. More dangerous ones include hyperthermia, uncontrollable seizures, high blood pressure and depression caused by a sudden drop in serotonin levels in the days after use, nicknamed Suicide Tuesdays. Glatter said. Payne had not heard of Molly before Since then, the agency has used the term to document arrests in Syracuse and Jackson, Miss. Cat Marnell, 30, the former beauty director at xoJane. Bigelow in the West Village. Marnell said. Weed smells too much and is also sort of low rent and junior high. But Ms. Her publicist said it was white chocolate. MDMA was first classified as an illegal substance in Those claims have since been disproved, according to Dr. In recent years, the Food and Drug Administration has approved studies looking into whether MDMA can be used to treat post-traumatic stress disorder and anxiety in terminal cancer patients. And Dr. Halpern has found no evidence that the drug impairs cognitive performance. But a greater worry for doctors and law enforcement officials is the many substances that people might be ingesting unknowingly when they take Molly. Payne of the D. According to Dr. Payne said. Despite promises of greater purity and potency, Molly, as its popularity had grown, is now thought to be as contaminated as Ecstasy once was. Halpern said. But to some users, Molly still feels like a more respectable substance than others. Prickett, who moved to New York from Toronto last year, added that she could see why the drug might be taking hold in her new habitat. MDMA, which in addition to acting as a stimulant also promotes feelings of bonding and human connection, just might be what people are looking for right now. Doblin said. Home Page World Coronavirus U.

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