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Interpol review of toxicology 2019–2022

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Vitreous humor VH shows excellent potential as a matrix of choice for postmortem analytical toxicology due to the ease of sampling and low metabolic activity. This study demonstrates a simple and rapid analytical method to identify and quantify 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxy-ethylamphetamine in VH. Samples were collected with a simple eye puncture procedure, followed by liquid—liquid extraction and derivatization with heptafluorobutyric anhydride and analysis via gas chromatography—mass spectrometry. Limits of detection and quantification ranged from 1. The validated method was successfully applied to detect methylenedioxyamphetamine derivatives in VH samples collected from victims of fatal car crashes. Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. 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Eduardo Geraldo de Campos. Lucas Blanes. Philip Doble. Bruno Spinosa De Martinis. Author to whom correspondence should be addressed. Email: martinis usp. Revision received:. Select Format Select format. Permissions Icon Permissions. Abstract Vitreous humor VH shows excellent potential as a matrix of choice for postmortem analytical toxicology due to the ease of sampling and low metabolic activity. Issue Section:. You do not currently have access to this article. Download all slides. Sign in Get help with access. Society of Forensic Toxicologists members Sign in through society site. Institutional access Sign in through your institution Sign in through your institution. Get help with access Institutional access Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. 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