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These datasets underpin the analysis presented in the agency's work. Most data may be viewed interactively on screen and downloaded in Excel format. All countries. Topics A-Z. The content in this section is aimed at anyone involved in planning, implementing or making decisions about health and social responses. Best practice. We have developed a systemic approach that brings together the human networks, processes and scientific tools necessary for collecting, analysing and reporting on the many aspects of the European drugs phenomenon. Explore our wide range of publications, videos and infographics on the drugs problem and how Europe is responding to it. All publications. More events. More news. We are your source of drug-related expertise in Europe. We prepare and share independent, scientifically validated knowledge, alerts and recommendations. About the EUDA. The content of this summary does not necessarily reflect the official opinion of the European Union, nor the official opinion of the Republic of Kazakhstan, and should be seen as the product of CADAP 5. Further information on drug situation in the Republic of Kazakhstan available on the website of the Monitoring Centre on Alcohol and Drugs. According to the data obtained in that study, the number of people dependent on drugs in the Republic of Kazakhstan was 1. Of these, The study found that 4. In view of the fact that the above study was conducted a number of years ago, currently there are no epidemiological studies that reflect the actual situation associated with drug use among the population. Key measures for the prevention of drug use are identified in the Resolution of the Government of the Republic of Kazakhstan No. In addition, each region approved regional programmes to combat drug abuse and drug trafficking. The performance of these programmes is reviewed annually. Regional programmes, like the national programme, are the basic instruments in the field of drug prevention and drug use among different population groups. In total, during the implementation of the Action Plan Programme for —11, more than 23 measures were organised, aimed at the primary prevention of drug abuse among young people and with a total coverage of over 1 million people. According to the Ministry of Tourism and Sports, particular attention is paid to the development of youth sports as alternatives to drug and alcohol use among young people. The Republican Centre for Healthy Lifestyles, which has branches in all the regions of Kazakhstan, plays an active role in the prevention of drug addiction and other diseases. It supports 17 youth health centres in the country, which provide comprehensive medical and psychosocial services, taking a friendly, accessible approach towards young people. Educational institutions still remain the major social institutions where most of the preventive measures take place. In , with the support of the United Nations Office on Drugs and Crime UNODC , an evaluation of preventive programmes in educational institutions took place in the country for the first time Espenova et al. This programme is now routine, and is carried out throughout the school year in each school. In accordance with the international definition, problem drug use PDU in the Republic of Kazakhstan is attributed primarily to injecting drug use. There are no reliable data on the use of cocaine, amphetamines and methamphetamines among the population of Kazakhstan. It should be noted that the high cost of these drugs in the country significantly limits their availability; most of the substances seized were attributed to the cities of Astana and Almaty. Recently, problems related to the emergence of desomorphine in the country have become apparent. Desomorphine is a home-made product that is manufactured from available codeine medications. Additionally, in there were reports in some regions of Kazakhstan indicating the abuse of tropicamide by drug users. At the end of , the estimated number of people who had injected drugs in the previous 12 months was in the figure was In there were 4 demands for inpatient care stemming from drug dependence, including 2 people who were seeking drug treatment for the first time in their life. The treatment demand indicator data collection covered In the past three years, the number of patients treated in state drug dispensaries has tended to decrease. At the same time, the number of people applying for drug treatment for the first time has shown an increasing tendency. For most cases, treatment is related to mental and behavioural disorders caused by the consumption of opioids F11 in the International Statistical Classification of Diseases and Related Health Problems, 10th Revision ICD , , and the combined consumption of psychoactive substances F19 in ICD, Opioids have been the most problematic drug among patients treated since In opioids were the primary drug for According to the demographic characteristics, the majority of patients treated in were male The average age of patients was Some Many of the patients The average number of hospitalisations among individuals who had been treated previously was 4. In a total of 17 people in Kazakhstan were human immunodeficiency virus HIV positive, of which In recent years the proportion of cases for which injecting drug use was the route of infection among newly diagnosed cases of HIV has been decreasing, while the proportion of cases of sexual transmission is increasing Republican AIDS Centre, a. According to a repeated sentinel bio-behavioural surveillance survey BBS , the prevalence of HIV infection among injecting drug users was 3. The prevalence of HCV was higher in people aged 25 and older The prevalence of syphilis among IDUs in was Over five years the prevalence of syphilis in IDUs was within the range 8. In the Republic of Kazakhstan a forensic medical examination is carried out in accordance with the law for all deaths related to poisoning, including overdoses on narcotics and psychotropic substances. The rate of overdoses on drugs and psychotropic substances per 1 inhabitants fell more than two times from 0. The proportion of the total number of poisonings with narcotic drugs and psychotropic substances who were classed as young people increased from 4. During this period, the proportion of women among the total number of overdoses on narcotic drugs and psychotropic substances also increased, from A comparison was made between the overall mortality rate in the population of the Republic of Kazakhstan in and the mortality rate among drug users except alcohol and tobacco , and the relative risk of death in the population of drug users as compared with mortality in the general population was calculated standardised mortality ratio — SMR. The SMR for men who use drugs was 2. The total SMR, including men and women who use drugs, was 2. The availability of a budget for outpatient treatment in some regions of the country especially in rural areas may be limited by the lack of primary healthcare PHC and a lack of professionals working in addiction treatment. Moreover, budgetary limitations on inpatient treatment result in low accessibility of treatment for people from remote areas and villages. In the public sector, hospital treatment of patients with drug and alcohol addiction is provided by 22 drug treatment clinics, five psychiatric hospitals and nine addiction clinics for compulsory drug treatment RSPC MSPDA, Outpatient drug treatment in was provided in cities by the dispensary departments of urban and regional drug treatment clinics 22 organisations , in small towns by the dispensary departments of psychiatric dispensaries five companies and in rural areas by drug advisory places in PHC organisations RSPC MSPDA, OST was first provided in the country in October Since the start of the OST project, individuals have attended it. No case of death from ingestion or overdose has been identified during the period of the project. Around Regional drug treatment clinics conduct annual monitoring of the proportion of patients in remission among all the patients of the dispensary who are registered as drug users. The purpose of the trust points is to provide safe injecting equipment and promote safe sexual behaviour among IDUs. In some 14 IDUs independently attended trust points, which is The direct coverage of prevention programmes of IDUs was In , the systematic coverage of IDUs by prevention programmes at least once per month was equal to In some Overdose prevention in the country is limited primarily to information and educational activities among drug users. These events are run by drug treatment organisations, AIDS centres, and specialised non-governmental organisations. Naloxone, which is the medicine often used in the prevention of overdoses among drug users, is available in healthcare facilities and has been added to the list of essential medicines in the country. Naloxone is used at ambulance stations and in emergency rooms in hospitals and intensive care units. However, it is not available in pharmacies. The main proportion of drug seizures in the Republic of Kazakhstan are of cannabinoids, which is due to the presence of wild cannabis in large areas country. In the past four years the volume seized from illegal drug trafficking has remained stable. In the total quantity of drugs seized was 33 tons kilograms Ministry of the Interior of Kazakhstan, The operational data of the Anti-Narcotics Committee of the Ministry of the Interior of Kazakhstan indicates that both wholesale and retail prices for all kinds of drugs increased significantly during —10; in prices remained at a similar level to According to the results of examinations conducted by the National Laboratory for the Legal and Scientific Support of State Control of Trafficking in Drugs, Psychotropic Substances and Precursors, it was found that the content of tetrahydrocannabinol in the marijuana that was seized ranged from 0. The purity of heroin varied from 1. During preparation for sale, diphenhydramine, citramon, analgin, aspirin, paracetamol and acetylsalicylic acid had been added, while in some cases, chloramphenicol, streptocid, sugar, baking soda, and citric acid had been used as cutting agents. Eighteen types of medicines containing codeine which is the raw substance for the preparation of desomorphine are registered. Of the reported drugs containing codeine, seven items are under strict control and 11 are not. Since codeine medications such as Solpadein, Yunispaz, Pentalgin-P or Antispazm have only been available by prescription. This measure is due to a sharp increase in the number of cases of abuse of these drugs Ministry of the Interior of Kazakhstan, According to the statistics of the Committee on Legal Statistics and Special Records of the General Prosecutor of the Republic of Kazakhstan, law enforcement authorities registered 4 crimes related to illicit trafficking in narcotic drugs, psychotropic substances and precursors in , as compared with 8 in , which represents a decrease of The crimes committed under Article of the Criminal Code, as a proportion of the total number of registered drug-law offences, was The basic document governing the legal basis of state policy in the field of narcotic drugs, psychotropic substances, and precursors and establishing measures to counter illicit trafficking is Law No. The commission of any acts storage, distribution, etc. Criminal liability for the sale of narcotic drugs or psychotropic substances is irrespective of the amount involved. Drug abuse is not a criminal offence in Kazakhstan. The same acts repeated within a year incur a higher fine. Administrative detention is provided for a person who has been arrested twice within a year for this act. It provides criminal penalties for the illegal purchase, transportation, or storage without the purpose of selling of narcotics or psychotropic substances in large quantities. Since , administrative responsibility has been stipulated for the commission of this act Part p. The main directions of the national drug strategy — a reduction in the demand for drugs, drug supply reduction, a reduction of consumption and harm reduction — are in line with international practices in drug policy. On the basis of Decree No. The main objective of the programme is the further improvement of the system of effective government and public opposition to drug addiction and drug trafficking. The activities of the programme involve the implementation of a number of legislative initiatives that, in general, follow the direction of the previous programmes: the introduction of alternative forms of punishment, which is provided for drug addicts who have committed minor offences, and alternatives to criminal sanctions imprisonment in the form of compulsory treatment of drug addiction. Additionally, on the basis of Decree No. In September an inter-agency committee was formed at the level of the Government of the Republic of Kazakhstan to coordinate the activities of state bodies aimed at combating drug abuse and drug trafficking. The country continues an active policy of integration and cooperation with international partners and other countries, strengthening the international legal framework in the fight against drug trafficking. This strategy sets out the general direction for improving the system against illicit drug trafficking, the prevention of drug abuse and the treatment and rehabilitation of drug addicts. Activities on a number of joint projects aimed at the improvement of the measures taken by governmental bodies to combat drug abuse and drug trafficking were performed. Espenova, M. Lavrentyev, O. Homepage Quick links Quick links. GO Results hosted on duckduckgo. Main navigation Data Open related submenu Data. Latest data Prevalence of drug use Drug-induced deaths Infectious diseases Problem drug use Treatment demand Seizures of drugs Price, purity and potency. Drug use and prison Drug law offences Health and social responses Drug checking Hospital emergencies data Syringe residues data Wastewater analysis Data catalogue. Selected topics Alternatives to coercive sanctions Cannabis Cannabis policy Cocaine Darknet markets Drug checking Drug consumption facilities Drug markets Drug-related deaths Drug-related infectious diseases. Recently published Findings from a scoping literature…. Penalties at a glance. Frequently asked questions FAQ : drug…. FAQ: therapeutic use of psychedelic…. Viral hepatitis elimination barometer…. EU Drug Market: New psychoactive…. EU Drug Market: Drivers and facilitators. Statistical Bulletin home. Quick links Search news Subscribe newsletter for recent news Subscribe to news releases. Breadcrumb Home Publications Overview of the drug situation in Kazakhstan Overview of the drug situation in Kazakhstan Contents Drug use among the general population and young people Prevention Problem drug use Treatment demand Drug-related infectious diseases Drug-related deaths Treatment responses Harm reduction responses Drug markets and drug-law offences National drug laws National drug strategy Coordination mechanism in the field of drugs References.
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Official websites use. Share sensitive information only on official, secure websites. The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Results: Among patients eligible for alcohol screening according to the inclusion criteria patients were screened The majority of physicians did not have difficulties in performing the intervention. However, the implementation depends on the willingness and interest of the PHCU and the physicians. Alcohol consumption is a significant risk to public health and a leading cause of morbidity and mortality \[ 1 — 3 \]. In addition to diseases in which alcohol consumption is a necessary cause e. Given this, implementing effective measures to address health and wider societal consequences of alcohol-related harm is a top international public health priority. Besides policy interventions such as increasing alcohol taxation, the WHO recommend the widespread implementation of brief psychosocial intervention for persons with hazardous and harmful alcohol use \[ 5 \]. A prime example for such an intervention is alcohol screening and brief intervention ASBI which is especially recommended to be offered by general practitioners GPs \[ 6 \]. Most hazardous and harmful drinkers consult their primary health care PHC providers and the greatest impact in addressing alcohol-related harm at a population level can be achieved by focussing on this larger group of hazardous and harmful drinkers. There is large scientific evidence that ASBI is effective and cost-effective in PHC settings \[ 7 — 10 \] and some evidence for small effects of ASBI on alcohol consumption reductions in emergency care settings \[ 11 \]. Screening patients for their alcohol use can be performed via conversation or using a formal screening instrument like the AUDIT-C \[ 12 , 13 \], a modification of the Alcohol Use Disorders Identification Test \[ 14 \]. Often, elements of Motivational Interviewing MI \[ 16 \] are used as part of the brief intervention technique \[ 17 \]. Manuals on brief intervention to support primary care workers have been published by the World Health Organization \[ 18 \]. Brief interventions can be supplemented by information material such as leaflets or brochures on risky alcohol consumption and its consequences. Several studies have demonstrated the importance of providing training to PHC physicians in order to increase their activity in measuring alcohol use and giving brief advice to heavy drinkers to help reduce their consumption \[ 19 — 21 \]. In Kazakhstan, the implementation of a multi-component alcohol prevention policy has been claimed to be a strategic approach in the public health system for over 20 years. It includes age boundaries for sale, taxation and advertisement regulations as well as time and space restrictions on consumption and sale \[ 22 \]. The measure of pure alcohol per capita is regarded as a generalized indicator of policy effectiveness and its reduction to 6. Although the PHC settings are claimed to play a pivotal role within the national preventive initiatives, their current alcohol prevention measures represent only a minor part of the comprehensive national screening programme addressing seven lifestyle risk factors for the population aged 30 years and above. About a half of those persons aged 15 years or older who had reported to use alcohol in , exhibited heavy episodic drinking behaviour \[ 24 \]. According to the official register of the Ministry of Health, the incidence of mental and behavioral disorders due to alcohol consumption in the Republic of Kazakhstan was In most of the cases, people who have hazardous and harmful drinking patterns are registered for dispensary and consultative observation. Compared to the other Central Asian countries, Kazakhstan has exhibited the highest prevalences for both indicators for many years. Brief interventions have been implemented in Kazakhstan in a number of pilot projects with limited sustainability. These observations are in accordance with the main barriers of implementation of ASBI found in the international literature: environmental context and resources, beliefs about capabilities, and lack of skills \[ 27 , 28 \]. The primary aim of this pilot cluster-randomised trial was to assess the feasibility of ASBI implementation in primary health care units PHCU in Kazakhstan and to compare its efficacy against simple feedback as a control intervention \[ 29 \]. The pilot study was designed as a two-arm cluster randomised trial in order to explore feasibility and acceptability in six PHCUs in Kazakhstan. Every PHCU has its own catchment area. Therefore, cross-contamination is negligible. In the 5 participating PHCUs in Pavlodar between 38 and 48 physicians treat about ,—, patients per year. Stratification was based on the assessment of the mean number of patient visits per PHCU per day. Three pairs of PHCUs with comparable doctor-patient ratio were formed. All patients with an appointment in the participating PHCU were eligible for recruitment. Participants had to be aged between 18—69 years, able to follow the study procedures, and have provided written informed consent. Patients with diagnosed lifetime alcohol dependency according to ICD criteria were excluded. The study started in summer , the screening was carried out in Patients of the IG with an AUDIT-C score of three or lower for females and four or lower for males received short verbal feedback based on their alcohol consumption and an information leaflet reinforcing the benefits of low-risk alcohol use. Patients of the CG received simple feedback, including information about their individual AUDIT-C score and the associated alcohol risk level, as well as a patient leaflet with recommendations for low-risk alcohol use. The booster group sessions were conducted within six to 8 weeks after the initial training. The trainers were experienced in Motivational Interviewing MI techniques and in providing training courses for health professionals \[ 29 \]. Patient variables were assessed at two time points, at baseline, concurrently with the screening and brief intervention process, and at 3-month follow-up. This final provider assessment was based on the results of two focus groups with both, participating physicians and physicians who had chosen to decline their participation in the trial. All participating physicians signed an informed consent. The statistical analyses were performed by using SPSS 25 \[ 30 \]. The RE-AIM framework for implementation studies was used to support the evaluation of feasibility and implementation outcomes \[ 33 \]. Outcome measures selected to assess the dimensions Reach and Effectiveness were the rate of eligible patients and the proportions of patients screened and intervened at baseline, and the change in AUDIT-C score between baseline and follow-up. The dimension Adoption included the proportion of staff that participated and their representativeness compared to non-participants. Difficulties and barriers for performing ASBI as well as the acceptance by the patients were the operationalized components of the dimension Implementation. The potential extent to which the intervention package becomes institutionalized and possible facilitators were the factors examined under the Maintenance dimension. The study was approved by the ethical board of the Kazakh National Medical University in Almaty application no. Study participation was based on informed consent. Deviating from the initial concept, five PHCUs took part, two in the interventional arm and three in the control arm. One PHCU dropped out of the study after the randomisation had taken place. The order of the local health authority was insufficient to motivate this facility to participate in the study. Out of physicians who had originally been invited to participate 56 for both, IG and CG , 24 of each group Screening was performed by 31 physicians Screening was carried out on working days between March and October In five different PHCUs 9, patients were treated by the participating physicians during that period. Overall, Thirteen patients in the IG The individual reasons for patient drop-out were not assessed due to loss of contact. At baseline around half of the patients screened in both groups were male Table 1. The patients in the IG were on average 4 years older than the control patients. About half of the patients in both groups were of Kazakh nationality. The patients in the IG had a higher level of education. Experiences with alcohol related questions and advice showed substantial differences between the study groups; they are less pronounced in the control arm. However, there were no significant group differences here. Among the 88 positive screened patients reached 3 months later for follow-up assessment, a marked and statistically significant reduction of AUDIT-C scores was observed Table 2. However, between the IG and CG there was no significant difference as measured by linear mixed-effects models analysis as well as by a comparison of the AUDIT-C change-score between the two groups. This difference also did not reach statistical significance. Time effect and difference between groups. Only a minority of patients followed-up had visited a psychiatrist or narcologist within the past 3 months total 4. Out of physicians originally invited 56 per group, Figure 1 , data were available for 99 persons, 31 participated in the trial The participating physicians did not differ significantly from non-participating physicians with regard to gender participants: If at all, bringing up the topic of alcohol in the presence of the patient and referring a patient in case of severe alcohol problems were the most problematic topics in conducting ASBI Table 3. Thus, these components of ASBI could be implemented in line with the study protocol. This is also true for delivering ASBI in general. One noteworthy difficulty or barrier for performing ASBI was the lack of compensation for additional work and the rejection of some patients Supplementary Table S1. However, too little time for delivering ASBI was viewed as the most significant problem by the physicians. On the other hand, the overall relevance of ASBI was not questioned. Here the instruction material provided to the physicians was rated as the most useful facilitator, closely followed by the patient information leaflet which also proved to be helpful in the consultation process. When asked about the time spent on the screening procedure, the majority of physicians From the patient perspective, nearly all persons who were reached for follow-up confirmed that they had received a personal feedback by the physician IG: Furthermore, The study outcomes indicate that screening for alcohol followed by a standardised brief intervention is feasible and can be implemented in PHC settings in Kasakhstan. Part of the feasibility trial was a follow-up evaluation of changes in drinking behaviour after 3 months which represented the effectiveness dimension of the RE-AIM framework. It was the expressed interest of the participating physicians and facilities to evaluate the effect of the screening and brief intervention within the pilot trial. Both approaches, ASBI and the provision of a standard alcohol leaflet can have the potential to achieve a substantial, positive public health impact. One key domain of the RE-AIM framework is the Reach component, the measure to what extent the target population has been reached. However, among the participating physicians in this trial we found an overall screening rate of Interestingly, the screening rate was more than two times higher in the CG simple feedback plus information leaflet compared to the IG formal ASBI plus information leaflet. Considering that the overall number of patients eligible for screening was less than the half in the control arm, one explanation could be, that the PHCU in the control arm had more time to screen their patients. The differences between the groups in experience with alcohol related questions and advice at baseline examination may be due to a misunderstanding among the patients of the two clinics who belonged to the intervention arm. The given study information and patient consent may have influenced the answer to this question. However, given the small number of PHCUs in the study and the differences between the PHCUs with regard to numbers of patients per unit, we are cautious to draw respective conclusions. Furthermore, the patients of the CG were younger at baseline and to a lesser extent had an academic degree. This can be an important confounder which may limit the comparability of IG and CG. A patient-wise randomisation was not possible in this trial. A future randomised controlled trial with more PHCUs and blockwise randomization instead of clustering is needed to provide further relevant data about alcohol screening and its effects in PHC settings in Kazakhstan. However, no significant differences in the reduction of hazardous drinking could be found between the groups. Both kinds of intervention—brief face-to-face alcohol intervention plus information leaflet vs. Given this, our study outcomes support previous findings that alcohol interventions followed by standardised screening procedures can be very brief \[ 8 , 10 , 36 \]. Out of more than one hundred PHC physicians invited to the training sessions, less than one third eventually took part in the study Adoption. As there were no statistical significant differences between participants and non-participants in terms of gender, work experience, overall job statisfaction, and attitudes towards patients with alcohol use disorders SAAPPQ , our study outcomes indicate that a respresentative sample of PHC physicians took part. However, not all of the 31 physicians participated in the survey on the implementation of ASBI and the study conditions. This applies to a greater extent to physicians of the control arm which could be a sign of limited study compliance in the CG. Previous studies have shown that training is a key component to increase the ASBI uptake and coverage in PHC settings \[ 37 \], also in low-middle income countries \[ 21 \]. With respect of the Implementation dimension of the RE-AIM approach, no major implementation problems in both groups of the participating physicians were observed, with the exception of insufficient time during the patient visit. This particular challenge was also stressed in the focus group discussions, by participating and non-participating physicians alike. Possibly, work overload has also kept individual physicians from attending the training. With regard to the entire project, one could argue that the moderate rate of participating physicians indicates implementation difficulties. Maintenance is the final dimension of the RE-AIM framework which is normally not easy to study within a time-restricted pilot trial. The physicians were asked if they would integrate the procedures of ASBI or simple feedback in their future practice, and the majority agreed to do so. This was even more the case for physicians in the ASBI arm, suggesting that these physicians considered the intervention package as helpful and effective. However, to what extent or if at all ASBI will be part of the routine diagnostic procedure in PHC practices cannot be answered by this pilot study. This study has some limitations. Planned as a pilot cluster-randomised trial the main outcome measure was feasibilty and to a certain extent efficacy of ASBI in PHC settings in Kazakhstan. The non-participation of one PHCU in the ASBI arm after randomisation required a higher engagement of the other two units which might have influenced the study outcomes. Within the framework of the present study it was not possible to substitute the non-participating facility, as the total number of public PHCUs in the closer Pavlodar area had already been included in the trial. Furthermore, it has to be considered, that the number of physicians in the control arm was low and the respective outcomes need to be handled with caution. In the study protocol we assumed that 4, patients needed to be screened to result in a sample size of patients with a positive AUDIT-C score \[ 29 \]. Although we reached the expected number of patients eligible for alcohol screening according to the inclusion criteria, only As a result, the number of patients with positive screening in both groups was low Furthermore, the follow-up rate among screen positive patients at baseline in the ASBI arm was low. Against the background of the by definition short intervention, a follow-up period of 3 months seems comparatively long and is likely to have a negative impact on the participation rate. However, since ASBI is intended to achieve a sustainable change in behavior, the observation period should cover at least a few weeks to reflect such a change \[ 38 \]. Thus, the effect analysis was based on a smaller number of patients than expected which led to a low statistical power, and it was carried out as a per protocol analysis only \[ 29 \]. Finally, the results on adoption were based on the responses of fewer than the invited physicians, and data on implementation were only available from 19 out of 31 physicians trained within the study. A general limitation of proving the effectiveness of ASBI even in a patient-wise randomised study is the fact that screening itself may have an impact on drinking behaviour and the additional effect of BI may be small and therefore not easily demonstrated statistically in a limited clinical trial. In this two-arm cluster randomised pilot trial we found that ASBI is feasible, that it can be implemented into PHC settings in Kazakhstan, and that it has positive effects on drinking behaviour if the intervention is accompanied by training and respective supporting material. Furthermore, the drop-out rate among physicians as well as the non-participation of an entire PHCU indicate that introduction of ASBI requires extensive planning and preparation with stakeholder involvement as well as an adequately financed implementation phase that takes into account the not only study-related additional effort. The identified barrier that physicians worked under strong time restraints could be encountered in a future trial by having specifically trained PHC nurses conduct the screening instead of the physicians. Also, a future trial should allow for substituting potential drop outs on the PHCU level with similar facilities. We would like to thank the participating doctors and patients for their contribution to the study. The studies involving human participants were reviewed and approved by Ethical board of the Kazakh National Medical University in Almaty application no. UV drafted the manuscript. All authors approved the version to be published. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This section collects any data citations, data availability statements, or supplementary materials included in this article. As a library, NLM provides access to scientific literature. Int J Public Health. Find articles by Uwe Verthein. Find articles by Harald Lahusen. Find articles by Marcus Sebastian Martens. Find articles by Mariya Prilutskaya. Find articles by Oleg Yussopov. Find articles by Zhanar Kaliyeva. Find articles by Bernd Schulte. Received Jan 28; Accepted Sep 27; Collection date Open in a new tab. Click here for additional data file. Similar articles. Add to Collections. Create a new collection. Add to an existing collection. Choose a collection Unable to load your collection due to an error Please try again. Add Cancel. Experience with alcohol related questions and advice past 12 months. Explaining the consequences and health risks associated with alcohol use. Referring patients in case of dependence or severe alcohol problems.
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