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mGluR7 Genetics and Alcohol: Intersection Yields Clues for Addiction

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Eur Addict Res 8 January ; 26 1 : 10— These differences are also found in the elevated mortality risk for CUs, higher among subjects with cocaine and heroin use. This study targeted residents in Northern Italy who turned to a public treatment center for drug addiction following problems caused by primary cocaine use between and Objectives: To estimate mortality risk for subjects who have never used heroin CUs compared to that of subjects who have used heroin HCUs. Method: Retrospective cohort study. We selected 1, subjects; 18, Person Years PY. Results: Over time, the quota of subjects injecting cocaine and using heroin decreased, while patients not using heroin increased. Both new patients and crude mortality rates CMR decreased during the years — and increased in the following period. CMRs were 5. Standardized mortality rates were 3. Among CUs, most of the deaths were from injury excluding drug related and tumors; among HCUs, from drug-related causes and diseases of the cardiovascular system. Conclusion: The study results show a change in the characteristics of SERD clients being treated for primary cocaine use, which are reflected both in mortality risk and causes of death. After a long period of a decrease, mortality risk increased in the period after the economic recession. Aspects concerning the effects of the economic recession on the problematic consumption of cocaine and on the risk of death are discussed. Sign In or Create an Account. Search Dropdown Menu. Advanced Search. Skip Nav Destination Close navigation menu Article navigation. Volume 26, Issue 1. Article Navigation. Research Articles October 16 This Site. Google Scholar. Samantha Sanchini ; Samantha Sanchini. Silvia Marani ; Silvia Marani. Elsa Turino ; Elsa Turino. Leonardo Tadonio ; Leonardo Tadonio. Barbara Cantarelli Barbara Cantarelli. Eur Addict Res 26 1 : 10— Article history Received:. Cite Icon Cite. You do not currently have access to this content. View full article. Sign in Don't already have an account? Buy Token. This article is also available for rental through DeepDyve. View Metrics. Email alerts Online First Alert. Latest Issue Alert. Citing articles via Web Of Science 6. CrossRef 6. Karger International S. Karger AG P. Karger AG, Basel. Close Modal.

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