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Prosecutors say year-old Encarnacion Reyes would buy large amounts of cocaine that he would mix with a cutting agent to increase its volume. People would drive or walk up to the house at all hours and would frequently approach a window adjacent to the garage of the home, authorities said. Officials say they received numerous complaints from members of the community about the alleged criminal activity starting earlier in the year. Authorities say a search of his home recovered around 1. Reyes allegedly took advantage of a supply shortage caused by the pandemic. He is also accused of running illegal dice and card games out of his home. Those gatherings often included more than 20 people throughout the pandemic, officials say. Reyes faces charges of operating as a major trafficker and multiple counts of criminal possession of a controlled substance and criminally using drug paraphernalia. If convicted, he faces a maximum sentence of 25 years to life in prison. Welcome, Mickey. Manage MyDisney Account. Log Out. Man accused of selling cocaine through 'take-out window' of Long Island home. Wednesday, August 26, Man accused of selling cocaine through 'take-out window' of home A man from Long Island is charged with running what authorities say was a major cocaine trafficking operation from a makeshift 'take-out window' at his home. Police want to identify the man caught on camera robbing a woman while she was holding her infant son. Report a correction or typo. Watch Live. Worker trapped after wall collapse at construction site in Bridgeport. Jury selection begins in deadly subway chokehold trial. Liam Payne had multiple drugs in his body at time of death: Sources. The Vessel reopens with new safety features at Hudson Yards. Sean Combs faces new rape allegations alongside unnamed celebrities. Frozen waffle products recalled due to possible listeria See list. Mets eliminated after loss to Dodgers in Game 6.

United States v. Encarnacion, No. 21-1165 (1st Cir. 2022)

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The Journal publishes articles on basic or clinical research relating to nephrology, arterial hypertension, dialysis and kidney transplants. It is governed by the peer review system and all original papers are subject to internal assessment and external reviews. The journal accepts submissions of articles in English and in Spanish languages. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Spain is the country with the greatest incidence of cocaine use in adults, 1,2 and consignments of levamisole-contaminated cocaine has increased in the last decade. According to the series, these may be the most common manifestations. To our knowledge, this would be the first publication with kidney biopsy in Spain. The patient was a year-old male referred for kidney failure and nephrotic syndrome evaluation. In the current admission he reported nocturia for the last few months, choluria, intermittent oedema and arthralgia in the left shoulder, elbow and knee. He denied the use of tobacco, toxins or any medicine. Laboratory test: haemoglobin 9. HLA-B27 negative. Chest X-ray, echocardiogram and abdominal—pelvic CAT scan with no significant findings. Determination of toxins in urine was positive for cocaine. The patient was questioned again and admitted to use of inhaled cocaine in the previous months. The kidney biopsy comprised 27 glomeruli: 3 with ischaemic changes, one with a fibrous crescent and the rest with segmental capillary tuft necrosis Fig. Methylprednisolone 1. After one month, serum creatinine level was 1. Levamisole is an anthelmintic agent that was used as an immunomodulator in humans until It promotes immune manifestations through various mechanisms: 1 it facilitates the actions of macrophages, B lymphocytes and T lymphocytes, and neutrophil chemotaxis; 2 it would alter immune tolerance and 3 it has direct toxicity on neutrophils and endothelial cells. A jumbled or discordant immune pattern may be a key to diagnosis. Discordance between the pattern by immunofluorescence and ELISA may also be seen, 1,6 and indeed was observed in this case. Neutropenia is also common. A genetic susceptibility due to positivity for the HLA-B27 antigen has been shown in certain cases. Given that cocaine use is illegal and patients tend to deny it, it is important to maintain a high degree of clinical suspicion to reach a diagnosis. ISSN: Previous article Next article. January - February Pages More article options. Letter to the Editor. DOI: Necrotizing glomerulonephritis in levamisole-contaminated cocaine use. Download PDF. Ana Esther Sirvent a ,. Corresponding author. This item has received. Under a Creative Commons license. Article information. Table 1. Full Text. Skin impairment a : Retiform purpura and skin necrosis PS: leukocytoclastic vasculitis or thrombotic microangiopathy Typical location on earlobes and pinnae. Khan, R. Cuchacovich, L. Espinoza, S. Lata, N. Patel, I. Vasculopathy, hematological, and immune abnormalities associated with levamisole-contaminated cocaine use. Semin Arthritis Rheum, 41 , pp. Espinoza, R. Cocaine-induced vasculitis: clinical and immunological spectrum. Curr Rheumatol Rep, 14 , pp. Gross, J. Brucker, A. Bahce-Altuntas, M. Abadi, J. Lipoff, D. Kotlyar, et al. A novel cutaneous vasculitis syndrome induced by levamisole-contaminated cocaine. Clin Rheumatol, 30 , pp. Ventura Vilamala, F. Med Clin Barc , , pp. Bermejo Barrera. ANCA-positive vasculitis induced by levamisole-adulterated cocaine and nephrotic syndrome: the kidney as an unusual target. Am J Case Rep, 14 , pp. Curr Opin Rheumatol, 25 , pp. McGrath, T. Isakova, H. Rennke, A. Mottola, K. Laliberte, J. Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease. Clin J Am Soc Nephrol, 6 , pp. Carlson, D. Tuot, K. Jen, B. Butcher, J. Graf, R. Sam, et al. Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. Medicine Baltimore , 93 , pp. Gulati, A. Lupus anticoagulant and ANCA associated thrombotic vasculopathy due to cocaine contaminated with levamisole: a case report and review of the literature. J Thromb Thromb, 34 , pp. Subscribe to our newsletter. Print Send to a friend Export reference Mendeley Statistics. Recommended articles. Epidemiology of Fabry disease in patients in hemodialysis Arterial thrombosis in a patient with nephrotic syndrome This work is licensed under a Creative Commons Attribution 4. Instructions for authors Submit an article Ethics in publishing Language Editing services. Article options. Are you a health professional able to prescribe or dispense drugs? Skin impairment a :. Retiform purpura and skin necrosis PS: leukocytoclastic vasculitis or thrombotic microangiopathy. Typical location on earlobes and pinnae. Also on limbs, trunk and flanks. Serological abnormality: joint presence of multiple autoantibodies:.

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