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Your doctor may occasionally change your dose to make sure you get the best results. Do not take in larger or smaller amounts or for longer than recommended.It may take 4 weeks or longer before your symptoms improve. You may have unpleasant side effects if you stop taking Duzela suddenly. Duzela is commonly used for treating generalized anxiety disorder, major depressive disorder, nerve pain associated with diabetes, fibromyalgia pain and chronic muscle or joint pain. Breaking or opening the pill may cause too much of the drug to be released at one time.Duzela is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. Try to take Duzela at the same time each day. Do not stop using Duzela without first talking to your doctor. The active ingredient present in Duzelais Duloxetine Hydrochloride. Keep using Duzela as directed. Swallow it whole. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourselfCall your doctor at once if you have any of these serious side effects while taking Duzela: nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), feeling like you might pass out, agitation, hallucinations, fever, fast heart rate, overactive reflexes; very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremor; easy bruising, unusual bleeding; painful or difficult urination; headache, trouble concentrating, memory problems, weakness, feeling unsteady, loss of coordination, fainting, seizure, shallow breathing or breathing that stops.Get emergency medical help if you have any of these signs of an allergic reaction to Duzela: skin rash or hive, difficulty breathing, swelling of your face, lips, tongue, or throat.Take Duzela exactly as prescribed by your doctor. Do not crush, chew, break, or open a delayed-release capsule.This is not a complete list of side effects and others may occur. DC, New Mexico, HI, Charlotte, Oklahoma, IN, Miami, Massachusetts, NE, Rhode Island, San Jose, WI, ME, Kansas City, UT, Kansas, Pennsylvania, Kentucky, Oakland, MO, Nebraska, DE, Washington, Ohio, Houston, TX, AR, Missouri, Jacksonville, Indianapolis, Louisiana, Connecticut, CA, Seattle, Vermont, Atlanta, MI, Illinois, Minnesota, Chicago, Nevada, Indiana, South Dakota, Pennsylvania, Alaska, PA, Michigan, WA, WV, Tennessee, Virginia Beach, Iowa, Fort Worth, Dallas, Mesa, Wisconsin, LA, MT, Austin, Tennessee, Milwaukee, South Carolina, California, MA, Cleveland, FL, California, Delaware, Georgia, New Hampshire, Utah, Georgia, Colorado Springs. Arizona, Sacramento, WYSan Antonio, MD, Nebraska, Oklahoma, Portland, ID, Florida, Oregon, Massachusetts, NC, Phoenix, Texas, AL, SD, Virginia, GA, VT, New Orleans, Washington, RI, North Carolina, Detroit, Long Beach, Oklahoma City, OR, NY, NM, KY, Brookhaven, Arizona, Mississippi, Hawaii, OH, San Francisco, Tucson, Louisiana, Oregon, Nevada, TN, Maryland, Idaho, Colorado, IA, North Dakota, Las Vegas, Boston, Philadelphia, KS, North Carolina, Fresno, Wyoming, District of Columbia, New York, New Mexico, El Paso, West Virginia, AZ, IL, CO, NH, Missouri, OK, Nashville-Davidson, Denver, Columbus, MN, District of Columbia, Virginia, MS, Maine, Michigan, Illinois, Minneapolis, Hempstead, Florida, Ohio, AK, Colorado, Washington, New Jersey, Honolulu, Baltimore, Tulsa, New York, Indiana, CT, Maryland, Minnesota, Texas, Albuquerque, SC, Wisconsin, ND, San Diego, Montana, NV, Omaha, Arkansas, NY, Alabama, NJ, Hawaii, VA, Memphis, Los Angeles,