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The main component of Apcalis SX Oral Jellyis Tadalafil. In more rare cases low blood pressure, blurred vision and changes in color vision, and abnormal ejaculation may occur.Most usual side effects of Apcalis SX Oral Jelly are facial flushing (reddening), headaches, stomach upset, diarrhea, flu-like symptoms and nausea. If you smoke tobacco and take Apcalis SX Oral Jelly concomitantly this may lead to a condition called NAION (sudden optic nerve-related vision loss). Take Apcalis SX Oral Jelly once daily and do not exceed the recommended dose. It results in relaxation of arterial smooth muscles and blood flow to the tissues of the penis that causes erections. Inform your doctor before to take Apcalis SX Oral Jelly if you have abnormal penis, including curved penis and birth defects of the penis, had coronary artery disease, arrhythmia, angina, heart attack or heart failure, hypo- or hypertension, bleeding, stomach ulcers, diabetes, hyperlipidemia (excess of lipids in the blood), sickle-cell anemia, liver or kidney failure in history. When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Tadalafil leads to increase of cGMP levels in the cavernous body of penis. Tadalafil has no effect when sexual stimulation is absent.It is preferable not to use Apcalis SX Oral Jelly with grapefruit juice, alcoholic beverages, tobacco. Apcalis SX Oral Jelly helps to achieve good erection during sexual intercourse and works improving blood flow in the penis relaxing arterial smooth muscles.The recommended dose of Apcalis SX Oral Jelly is 20 mg it should be taken at least 16 minutes before the sexual activity. If your erection is longer than 4 hours, seek for immediate medical help as it may permanently damage your penis.Apcalis SX Oral Jelly is contraindicated in patients who are using any form of organic nitrate, either regularly and/ or intermittently as it is able to potentiate hypotensive effect of nitrates. Prolonged erections or priapism (painful erections lasting more than 6 hours) are also possible.Apcalis SX Oral Jelly is an effective, reversible, selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). It works only when sexual stimulation is present. The effect persists during 36 hours. Aggravation of heart problems in patients with pre-existing heart disease using Apcalis SX Oral Jelly was reported. Boston, San Diego, FL, Indiana, Alaska, Oregon, Dallas, Delaware, TX, North Carolina, OK, Utah, Massachusetts, Texas, KY, Ohio, Memphis, Oklahoma, ME, AZ, Sacramento, Phoenix, Miami, Long Beach, DE, AL, Wisconsin, Oklahoma, NH, IA, AR, MO, Atlanta, Albuquerque, West Virginia, Jacksonville, CT, New Jersey, New Mexico, District of Columbia, WA, IL, Indiana, Idaho, New York, UT, Kansas City, Tucson, LA, San Francisco, North Dakota, San Jose, Mesa, Austin, Colorado Springs. Arizona, Charlotte, NY, Missouri, NC, WYRI, Maryland, MT, Hawaii, Tennessee, Nashville-Davidson, Missouri, Arkansas, Wisconsin, Hawaii, Louisiana, Maryland, AK, Seattle, Connecticut, MD, Washington, MN, NY, IN, New Orleans, NM, New Hampshire, Mississippi, North Carolina, Nevada, CA, Columbus, VT, SC, Tulsa, Washington, Washington, Minnesota, Kentucky, Colorado, Pennsylvania, Oakland, Maine, MA, Oklahoma City, Nevada, Nebraska, San Antonio, NE, Arizona, ID, Philadelphia, GA, Iowa, Louisiana, Baltimore, WV, Cleveland, ND, Indianapolis, SD, Chicago, Colorado, Alabama, KS, Illinois, DC, Florida, Minneapolis, Portland, Massachusetts, Hempstead, California, Brookhaven, Rhode Island, Las Vegas, Los Angeles, New Mexico, Nebraska, Tennessee, Houston, NV, WI, Florida, South Carolina, Oregon, Georgia, District of Columbia, Omaha, Denver, Virginia Beach, OR, Minnesota, Kansas, Pennsylvania, South Dakota, PA, El Paso, New York, MI, Honolulu, Fresno, TN, Michigan, Milwaukee, HI, MS, Ohio, Virginia, CO, Fort Worth, Georgia, VA, Michigan, Detroit, Illinois, California, Montana, Vermont, NJ, Virginia, OH, Texas, Wyoming,