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Buy 4-BMC online from Chem14.com. Premium laboratory-grade 4-bromomethcathinone with 98% purity, third-party testing, and discreet worldwide shipping available now.
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4-BMC (4-Bromomethcathinone), also known as brephedrone, is a synthetic cathinone research chemical available in laboratory-grade powder form. Our product exceeds 98% purity and comes with third-party certificates of analysis for quality assurance.
Key specifications:
- CAS Number: 486459-03-4
- Molecular Formula: C₁₀H₁₂BrNO
- Molecular Weight: 242.11 g/mol
- Form: Crystalline powder
- Purity: >98%
- Applications: Neuroscience research, analytical chemistry
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How to buy 4-BMC online (the best research chemical vendor in the USA: what you need to know in 2026) 🔬
4-BMC (4-Bromomethcathinone) is a synthetic cathinone research chemical with CAS number 486459-03-4, acting as a serotonin-norepinephrine-dopamine releasing agent for neuroscience studies.
We at Chem14.com understand that sourcing high-quality research chemicals requires trust, transparency, and consistent supply. As one of the leading research chemical vendors in the USA, we provide laboratory-grade compounds that meet the highest standards of purity and reliability.
This comprehensive guide covers everything you need to know about 4-BMC, from its chemical profile and pharmacology to legal status and safe purchasing practices.
What is 4-BMC (4-bromomethcathinone)? 🧪
4-BMC is a synthetic cathinone derivative with molecular formula C₁₀H₁₂BrNO, classified as a psychoactive phenethylamine compound used exclusively for laboratory research purposes.
Also known as brephedrone, this compound belongs to the substituted cathinone family, sharing structural similarities with other para-halogenated cathinones like 4-CMC and 3-CMC [[36]]. The substance acts primarily as a serotonin-norepinephrine-dopamine releasing agent (SNDRA), making it pharmacologically interesting for neuroscience research [[42]].
First identified in forensic reports around 2014, 4-BMC has gained attention from researchers studying novel psychoactive substances and their metabolic pathways [[34]]. The European Union Drugs Agency (EUDA) began monitoring this compound as a new psychoactive substance, noting increased availability across European markets since 2024 [[1]].
Chemical structure and classification
- Chemical class: Synthetic cathinone
- Subclass: Para-halogenated substituted cathinone
- IUPAC name: 1-(4-bromophenyl)-2-(methylamino)propan-1-one
- Core structure: β-ketone phenethylamine analogue
What is the CAS number and chemical profile of 4-BMC? ⚗️
4-BMC has CAS number 486459-03-4, molecular formula C₁₀H₁₂BrNO, molecular weight 242.11 g/mol, and appears as a white to off-white crystalline powder.
Understanding the precise chemical identity of any research compound is fundamental for proper documentation and experimental reproducibility. According to PubChem, 4-Bromomethcathinone carries multiple identifiers across chemical databases [[44]].
What is the pharmacological profile of 4-BMC? 💊
4-BMC functions as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) with secondary reuptake inhibition properties affecting all three monoamine systems.
The pharmacology of 4-BMC centres on its interaction with presynaptic monoamine transporters. Research indicates that this compound interacts with serotonin transporters (SERT), norepinephrine transporters (NET), and dopamine transporters (DAT) [[45]]. This triple-action mechanism distinguishes it from compounds that primarily target single neurotransmitter systems.
Mechanism of action explained
The primary mechanism involves substrate-type activity at monoamine transporters, causing reverse transport and subsequent release of neurotransmitters into the synaptic cleft [[47]]. This differs fundamentally from reuptake inhibitors, which simply block transporter function without inducing release.
Studies on related para-halogenated cathinones demonstrate that the bromine substitution at the para position influences both potency and selectivity compared to chloro or methyl analogues [[40]]. The acute effects observed in research settings share similarities with other synthetic cathinones like mephedrone (4-MMC) [[32]].
Receptor binding characteristics
- Dopamine release: Significant activity at DAT
- Serotonin release: Moderate to high activity at SERT
- Norepinephrine release: Substantial activity at NET
- Reuptake inhibition: Secondary mechanism of action
What are the effects and side effects of 4-BMC? ⚠️
4-BMC produces stimulant effects similar to related cathinones, with documented adverse reactions including cardiovascular complications, anxiety, neurotoxicity, and potential addiction liability.
As with all synthetic cathinones, 4-BMC possesses both neurotoxic and cytotoxic properties that researchers must consider when handling this compound [[36]]. The European Union Drugs Agency notes that acute effects likely mirror those of related substances such as 4-MMC [[32]].
Reported research observations
Based on studies of structurally similar cathinones, researchers have documented several categories of effects:
Stimulant properties:
- Increased locomotor activity
- Elevated alertness
- Enhanced energy levels
Adverse effects documented:
- Cardiovascular issues (tachycardia, hypertension)
- Anxiety and agitation
- Bruxism (teeth grinding)
- Tremors
- Potential for addiction [[37]]
Neurotoxicity concerns
Research published in peer-reviewed journals indicates that cathinones, including 4-BMC, demonstrate neurotoxic potential affecting dopaminergic and serotonergic neurons [[50]]. This property makes proper handling procedures essential for laboratory safety.
"Synthetic cathinones represent the second largest and most frequently seized group of new psychoactive substances globally." [[55]]
For researchers studying harm reduction or toxicity, our research ethics and safety guidelines provide comprehensive protocols.
What is the legal status of 4-BMC in the UK, USA, and EU? ⚖️
4-BMC is classified as Class B in the UK, Schedule I in Virginia (USA), Class F2 in Brazil, and controlled under NpSG in Germany, with EU-wide control implemented in 2026.
The legal landscape for 4-BMC varies significantly by jurisdiction, and researchers must understand their local regulations before procurement. According to Wikipedia, this substance carries specific classifications across multiple countries [[36]].
Important legal disclaimer
We strongly advise all customers to verify their local laws before ordering. Chem14.com sells research chemicals strictly for legitimate scientific purposes. Please review our legal disclaimer for complete terms.
Where to buy 4-BMC online safely in 2026? 🛒
Chem14.com offers premium 4-BMC with 98% purity, third-party testing, certificates of analysis, and discreet worldwide shipping at competitive prices starting from €205.
Finding a reliable research chemical supplier requires careful evaluation of multiple factors. We at Chem14.com have established ourselves as a trusted source through transparency, consistent quality, and responsive customer service.
Why choose Chem14.com for 4-BMC?
- Purity guarantee: Every batch exceeds 98% purity
- Third-party testing: Independent certificates of analysis available
- Discreet packaging: Plain, unmarked shipping materials
- Worldwide delivery: Serving researchers globally
- Competitive pricing: Bulk discounts available
- Secure payment: Multiple payment options
Our quality assurance process
- Raw material sourcing from verified chemical manufacturers
- In-house testing using HPLC and mass spectrometry
- Third-party verification by independent laboratories
- Certificate issuance with every order
- Batch tracking for complete traceability
Visit our stimulants category to view current stock and pricing.
How to order 4-BMC from Chem14.com? 📦
Ordering 4-BMC from Chem14.com requires account creation, age verification, product selection, secure payment, and confirmation with tracking provided within 24 hours.
Our streamlined ordering process ensures a smooth experience from selection to delivery. Follow these steps to place your order:
Step-by-step ordering guide
- Create an account at Chem14.com
- Verify your age (18+ requirement)
- Browse our stimulants collection
- Select 4-BMC and choose quantity
- Add to cart and proceed to checkout
- Choose payment method (cryptocurrency, bank transfer)
- Confirm order and receive confirmation email
- Track shipment using provided tracking number
For detailed instructions, see our how to order page.
Payment and shipping information
- Payment methods: Bitcoin, Ethereum, bank transfer
- Processing time: 24-48 hours after payment confirmation
- Shipping options: Standard (7-14 days), Express (3-5 days)
- Reshipping policy: Free reshipment if package seized
Which other research chemicals are similar to 4-BMC? 🔍
Related compounds include 4-CMC, 3-CMC, 2-MMC, mephedrone, and other para-substituted cathinones available in our stimulants category for comparative research studies.
Researchers studying structure-activity relationships often examine multiple related compounds. Our stimulants category contains several cathinones suitable for comparative analysis.
Similar research chemicals available
CompoundCAS NumberSubstitutionStatus4-CMC80329-57-3Para-chloroAvailable3-CMC1092658-89-7Meta-chloroAvailable2-MMC1235779-09-8Ortho-methylAvailable4-MMC (Mephedrone)186028-79-5Para-methylCheck availability3-MMC1189730-73-3Meta-methylAvailableWe also stock various psychedelic research chemicals, dissociatives, and benzodiazepines for comprehensive research programmes.
Why is 4-BMC popular in neuroscience research? 🧠
4-BMC attracts neuroscience research interest due to its triple monoamine releasing properties, structural novelty as a brominated cathinone, and value in studying structure-activity relationships.
The scientific community values 4-BMC for several reasons that make it particularly useful for specific research applications.
Research applications
Neuropharmacology studies:
- Investigation of SNDRA mechanisms
- Comparison with amphetamine analogues
- Metabolic pathway analysis [[15]]
Structure-activity relationship research:
- Role of halogen substitution
- Potency comparisons across cathinones
- Transporter selectivity studies [[48]]
Toxicology research:
- Neurotoxicity assessment
- Cytotoxicity evaluation
- Comparative harm studies
A 2024 study published in the AAPS Journal specifically examined the human metabolic profiling of 4-BMC alongside 3-CMC and 4-CMC, documenting major metabolic pathways for consumption detection [[34]].
When will 4-BMC ship and how long does delivery take? 🚚
4-BMC orders ship within 24-48 hours of payment confirmation, with standard delivery taking 7-14 days and express options available for 3-5 day delivery worldwide.
We understand that timely delivery matters for research continuity. Our logistics team works efficiently to minimise waiting times.
ur order anytime through our order tracking page.
Discreet shipping guarantee
All packages ship in plain, unmarked materials with no indication of contents. Return addresses use neutral business names. We maintain strict confidentiality throughout the shipping process.
Frequently asked questions about 4-BMC ❓
What is the difference between 4-BMC and 4-CMC?
4-BMC contains a bromine atom at the para position while 4-CMC contains chlorine, resulting in different molecular weights, potencies, and pharmacological profiles for comparative research.
The bromine substitution in 4-BMC (molecular weight 242.11) creates a heavier molecule compared to 4-CMC (molecular weight 211.69). This structural difference influences both the pharmacological properties and metabolic pathways of each compound [[40]].
Is 4-BMC legal to purchase in the USA?
4-BMC lacks federal scheduling in the USA but remains controlled in specific states like Virginia, requiring researchers to verify their state laws before purchasing.
Federal law does not currently list 4-BMC as a controlled substance, but individual states maintain their own regulations. Virginia classifies it as Schedule I [[36]]. Always consult local regulations before ordering.
How should 4-BMC be stored for research purposes?
4-BMC should be stored in a cool, dry place away from light and moisture, ideally at 2-8°C in an airtight container to maintain chemical stability and prevent degradation.
Proper storage preserves compound integrity for accurate research results. We recommend:
- Temperature: 2-8°C (refrigerator)
- Protection from light
- Desiccant packets for moisture control
- Original packaging when possible
What purity level does Chem14.com guarantee for 4-BMC?
Chem14.com guarantees 4-BMC purity exceeding 98%, verified through third-party testing with certificates of analysis provided with every order.
Our quality control process includes both in-house testing and independent verification. Each batch receives a unique certificate documenting exact purity levels and any detected impurities.
Can 4-BMC be used for human consumption?
4-BMC is strictly sold for laboratory research purposes only and must never be consumed by humans, as it remains an unapproved research chemical without safety data for human use.
We cannot emphasise this strongly enough. Chem14.com sells research chemicals exclusively for legitimate scientific research. Our research ethics guidelines outline proper handling procedures.
Key takeaways 📝
- 4-BMC (4-Bromomethcathinone) is a synthetic cathinone with CAS number 486459-03-4
- Acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA)
- Molecular formula: C₁₀H₁₂BrNO, molecular weight: 242.11 g/mol
- Legal status varies: Class B in UK, controlled in EU since 2026
- Chem14.com offers >98% purity with third-party testing
- Store at 2-8°C in airtight containers away from light
- Research chemical only, not for human consumption
Ready to order 4-BMC for your research?
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References
- European Union Drugs Agency. Initial report: 4-BMC. EUDA, 2025.
- PubChem. 4-Bromomethcathinone (CID 10421832). National Library of Medicine.
- Wikipedia. 4-Bromomethcathinone. Wikimedia Foundation.
- SWGDRUG. 4-Bromomethcathinone monograph. Scientific Working Group for the Analysis of Seized Drugs.
- Benchchem. 4-Bromomethcathinone technical guide. Benchchem Corporation.
- Springer. 3-CMC, 4-CMC, and 4-BMC human metabolic profiling. AAPS Journal, 2024.
- UK Government. Synthetic cathinones: updated harms assessment. Home Office, 2024.
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