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What is gynaecomastia and how is it caused by Risperdal?
A BOY who grew boobs “bigger than the girls at school” is joining thousands suing Johnson & Johnson after a fellow Risperdal victim won a £6billion payout.
Eddie Bible, a victim who began taking the drug at the age of 13, had corrective surgery to remove excess breast tissue in the US.
During an interview with CNN about his distressing experience, the Oklahoma man - now aged 26 - recalled feeling shame when seeing his large breasts in the mirror as a teen.
He said: "I had bigger boobs than the girls in (high) school. I thought, 'am I going to have to get a training bra?'"
Bible is among thousands of Risperdal lawsuits awaiting a decision following a landmark £6billion win in punitive damages from Johnson & Johnson in America.
The Sun Online reported yesterday how Nicholas Murray won the massive payout in punitive damages at a court in Philadelphia.
Looking back on it, I feel like an experiment.
The jury this week awarded the money to Murray, who previously won $680,000 (£556,000) over his claims that it failed to warn that young men using Risperdal could grow breasts.
J&J called the sum “grossly disproportionate with the initial compensatory award” and said it was confident it would be overturned.
Murray - like other male plaintiffs in the mass tort litigation over Risperdal - claims he developed breasts after he took the anti-psychotic drug as a child when diagnosed with autism spectrum disorder.
In Bible's case, he was prescribed the medicine as a teen to treat anxiety and bipolar disorder.
But, just 18 months later, he suffered from gynaecomastia - sometimes referred to as "man boobs".
The US Food and Drug Administration approved the drug in late 1993 for treating schizophrenia and episodes of bipolar mania in adults.
Penney & Associates Injury Lawyers said that in 2006, J&J finally put on the drug’s label that one of the major side-effects was gynaecomastia, breast growth in men.
The law firm said: "This condition has affected men of various ages, and persists after the drug is no longer used.
"Breast reduction surgery is often not covered by insurance plans, meaning that many victims would have to pay out of pocket to deal with the condition in this way."
Bible claims that his life was affected considerably by the side-effects.
As his breasts grew, he withdrew from social life whenever possible, because of the humiliation.
While at school, he experienced ridicule and mistreatment that would haunt him years later.
He said: “Looking back on it, I feel like an experiment."
Bible claims that had he known of the side-effect in question he would have never taken the drug to begin with.
Penny & Associates says that "over 13,000 plaintiffs are expected to file a pharmaceutical injury lawsuit against J&J".
Plaintiffs claim that the firm failed to warn of the risk of gynaecomastia, associated with Risperdal, which they say the company marketed for unapproved uses with children.
Jason Itkin, a personal injury lawyer representing victims at Arnold & Itkin, said: "This is a company that’s supposed to help people and instead has gone out of their way to hurt kids.
Representatives at the pharmaceutical giant insist that the drug remains an essential product for its intended users, citing millions who have used the drug without serious side-effects.
However, victims such as Bible still bear the scars of their breast reduction surgeries.
Children grab you to try to figure out what you are.
Many former Risperdal users also continue to suffer social side-effects long after they stopped using the drug.
Arturo Carino was driven out of high school after being allegedly abused by other students.
Now aged 23, he has not graduated from high school, nor can he afford corrective surgery.
Carino recalled: "Children grab you to try to figure out what you are.
"If I have this for the rest of my life, I’m probably not going to have a significant other.”
J&J is also facing lawsuits involving its baby powder , opioids , medical devices and other products.
Gynaecomastia - sometimes referred to as "man boobs" - is a common condition that causes boys' and men's breasts to swell and become larger than normal.
It is most common in teenage boys and older men, says the NHS .
Gynaecomastia can be caused by an imbalance between the sex hormones testosterone and oestrogen.
Oestrogen causes breast tissue to grow.
Risperdal is an anti-psychotic drug - anti-psychotics reportedly cause gynaecomastia by increasing levels of a hormone, prolactin, which stimulates breast growth and milk production in women.
Risperdal is also one of the worst atypical antipsychotics in producing gynaecomastia.
If the condition is not addressed early, it can lead to the growth of permanent breast tissue that remains even after the drug is discontinued.
In many cases, liposuction, breast reduction surgery, and surgical removal of the breast may be required.
Signs vary from a small amount of extra tissue around the nipples to more prominent breasts.
While all men produce some oestrogen, they usually have much higher levels of testosterone, which stops the oestrogen from causing breast tissue to grow.
If the balance of hormones in the body changes, this can cause a man's breasts to grow.
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My son has put on weight and grown breasts and body hair – he's only nine
I don't think our GP is taking this seriously enough – he seems to think I'm to blame for the weight gain. Meanwhile, my boy's confidence is suffering
Original reporting and incisive analysis, direct from the Guardian every morning
© 2022 Guardian News & Media Limited or its affiliated companies. All rights reserved. (modern)
My son was nine earlier this month. About six months ago, he suddenly put on a lot of weight and hair under his arms and his genitals began to grow. He has a fairly healthy diet and does a lot of exercise. I took him to our family doctor, who weighed him and said he wasn't worried; the fact that I had my first period at 10 explained everything.
Six months later, he has put on even more weight. He has breasts and the flab around his stomach leaves me in tears. His father and I are health conscious and go to the gym four or five times a week. We don't know what to do. Our son refuses to go swimming without a shirt on and wants to stop athletics because he can't keep up with the other children.
In July, he complained of aches and pains in his bones. This time, the GP said it could be growing pains or because he's overweight. He said most parents with overweight children simply give their children too much or the wrong food. We kept a food diary for a month and went back but I got the impression that he wasn't convinced. I insisted on a referral to a paediatrician. He agreed but made it clear he thinks my son's weight gain is my fault. This morning, I received a hospital appointment for the weight management clinic.
I feel his weight gain and hair growth is connected, but my GP has made me feel like a neurotic woman. My son, however, is suffering – I see his confidence being eroded. He refuses to eat breakfast and we have resorted to threats, which leaves us all depressed. He's usually an active, happy boy with lots of friends in and out of the house but hasn't invited anyone over since school started in September. He's been invited to five birthday parties and has asked me to make excuses for all but one. Please help.
Your GP is right: early, or late, puberty can run in families. ( Early onset puberty is classed as before the age of nine in boys, eight in girls.) But I wouldn't be so sure that "explains everything". You say you and your husband go to the gym four or five times a week, so I want to check how subjective your view is. And how much weight is "a lot of weight". That said, I do believe in a parent's instinct, and if you think something is not right, you must press for a proper assessment.
I showed your letter to Professor Peter Hindmarsh , who is professor of paediatric endocrinology at University College London, and it is with his help that I am replying. Obviously, I want to make it clear that it would be irresponsible to make a diagnosis in this column and I am not offering one. A doctor needs to see your son and run tests to find out if anything is amiss and, if so, what.
At the start of puberty, a child can start to put a little weight on and grow hair, but in boys, says Professor Hindmarsh, "It is usually an increase in muscle mass, not fat mass".
Growing hair in the places you mention is commensurate with puberty. In boys, growing breasts (if it's not simply a bit of excess fat) is not. I am not happy with your GP brushing off your son's pain as just growing pains, either. Thus I would urge you to go back to your GP (is there another one at the surgery? If you need back up, take your husband with you) and insist on an appointment to see a paediatric endocrinologist (some weight management clinics include one so check to see if the clinic you are going to does. If not, ask for a straight referral).
You are entitled to a referral to a specialist and, really, your GP cannot tell if something needs to be attended to or not, simply by putting your child on the scales.
I can imagine your son is confused and worried, as you are too. Until you have some concrete answers, you need to manage your worries so as to limit how much this filters through to him. Because your son feels out of control of the situation, he is trying to control what he can – in this case, his eating and extra-curricular engagements.
I know it's hard, but you might have to fake a bright and breezy approach.
Obviously you don't want your son to turn into a recluse, so I would talk to him and say something like, "We're going to get you some tests to make sure something isn't out of balance in your body. So until we know, let's eat healthily and try to live normally."
It may help him to get some books on puberty (my favourite is What's Happening to Me? by Alex Frith and Nancy Leschnikoff, published by Usborne) to explain the perfectly normal changes that do happen around his age. Although I would encourage your son to carry on as normal, if he really doesn't want to go out, don't force him and don't punish him. Keep me posted.
Contact Annalisa Barbieri, The Guardian, Kings Place, 90 York Way, London N1 9GU or email annalisa.barbieri@mac.com. Annalisa regrets she cannot enter into personal correspondence.
Follow Annalisa on Twitter @AnnalisaB
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Younger men have a thing for Jennifer Lopez — both on screen and off.
In the upcoming thriller The Boy Next Door , Lopez stars as Claire, a recently divorced teacher who falls for her much younger neighbor, Noah (played by Ryan Guzman).
In the clip above, exclusively on Yahoo Movies, the barely legal Noah makes a move on Claire like a veteran ladies man, offering her a rare copy of The Iliad and complimenting her looks (instead of her shoes). Ultimately, however, their relationship takes a dark turn.
Does Lopez’s art imitate life? A bit. The 45-year-old performer and self-professed “love addict” has defended her past relationship with Casper Smart, 20 years her junior. “ We are desirable older, we can date younger guys and it’s not this big taboo,” Lopez recently told Self magazine . “ Men have been doing this for years, and it’s no big deal.”
Lopez also admitted she relates to her character in Boy . "I've dated a younger guy once in my life," she said, referring to Smart, with whom she split in June . The entertainer, who is single at the moment, added, "I could definitely understand that part, too — the attraction."
You can see if J.Lo’s fictional attraction is of the fatal variety when The Boy Next Door hits theaters Jan. 23.
Crucially, the security official's testimony appears to confirm part of what Cassidy Hutchinson previously testified.
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