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Jump to navigation. Carbon nanotubes glow brighter in the presence of neurotransmitters. This facilitates the easy and accurate measurement of signals between nerve cells. Dopamine is an important signalling molecule for nerve cells. Its concentration could not be precisely determined with both high spatial or temporal resolution until now. These sensors visualise the release of dopamine from nerve cells with unprecedented resolution. Moreover, the chemical signals are altered by drugs such as cocaine and play a role in substance abuse disorders. This is where the novel sensors come into play. They are based on ultra-thin carbon tubes, about 10, times thinner than a human hair. When irradiated with visible light, they glow in the near-infrared range with wavelengths of 1, nanometres and more. In addition, there are far fewer background signals in this range that can distort the result. This is how his research group has succeeded in turning carbon nanotubes into tiny nanosensors that specifically bind to dopamine and fluoresce more or less strongly depending on the dopamine concentration. In order to do this, the sensors have to be moved into the vicinity of functioning neuronal networks. This allowed the researchers to visualise individual dopamine release events along neuronal structures for the first time and gain insights into the mechanisms of dopamine release. Daniel: A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites, in: PNAS, , DOI: Press release. Physical chemistry. Coating healthy nerve cells with a sensor layer In order to do this, the sensors have to be moved into the vicinity of functioning neuronal networks. Cooperation partners. Original publication. Press contact. Download high-resolution images. The selected images are downloaded as a ZIP file. The captions and image credits are available in the HTML file after unzipping. Selected press releases. English News. German News. A-Z N K. Impressum Kontakt. Seitenanfang y Kontrast N.

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