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Bk mdma

It is a member of the substituted amphetamine , substituted cathinone and substituted methylenedioxyphenethylamine classes. Methylone is the substituted cathinone analog of MDMA and the 3,4- methylenedioxy analog of methcathinone. Methylone does not substitute for amphetamine or for the hallucinogenic DOM in animals trained to discriminate between these drugs and saline. In vitro , methylone has one third the potency of MDMA at inhibiting platelet serotonin accumulation and about the same in its inhibiting effects on the dopamine and noradrenaline transporters. In spite of these behavioral and pharmacological similarities between methylone and MDMA, the observed subjective effects of both drugs are not completely identical. Alexander Shulgin wrote of the former: It has an almost antidepressant action, pleasant and positive, but not the unique magic of MDMA. The two major metabolic pathways in mammals for methylone are N - demethylation to methylenedioxycathinone MDC , and demethylation followed by O - methylation of the 3- or 4- hydroxy group to 4-hydroxymethoxymethcathinone HMMC or 3-hydroxymethoxymethcathinone 3-OHMeO-MC. Analysis of 'Explosion' has confirmed that the active ingredient is methylone. In the Netherlands, methylone is not yet listed under the Opium Law , but is covered under the medicine act. Because methylone is not registered officially, as such, it is forbidden to trade in methylone. The Minister of Health has asked the Coordination point Assessment and Monitoring new drugs group CAM to gather information about this substance, resulting possibly in an official risk assessment. In New Zealand, although methylone is not explicitly scheduled and falls outside the strict definitions of an 'amphetamine analogue' in the Misuse of Drugs Act, it is considered to be 'substantially similar' to methcathinone and is thus considered by law enforcement authorities to be a Class C illegal drug. The product was withdrawn after legal disputes with the government. Before this it was not specifically mentioned in United Kingdom U. In March , plans were announced to make methylone and other cathinones, Class B drugs, 'within weeks'. While delayed by dissatisfaction in the Advisory Council on the Misuse of Drugs , the revision was rushed through by the government with little regard for the views of the Council. The importation of the compounds was banned immediately. Sveriges riksdag added methylone to schedule I 'substances, plant materials and fungi which normally do not have medical use' as narcotics in Sweden as of Oct 1, , published by Medical Products Agency in their regulation LVFS Although not listed as a Schedule 1 \\\\\\\\\\\\\\\\\[17\\\\\\\\\\\\\\\\\] substance, Health Canada reports that methylone falls under the scheduling as an analogue of amphetamine. However, Methylone bears the exact chemical difference between amphetamine and cathinone - and cathinone is listed as not being an analogue of amphetamine, possibly implying that methylone is unscheduled in Canada. As of October 21, the DEA has issued an emergency ban on methylone. It is illegal to possess and distribute. Aside from context, they can be distinguished by the fact that the name will usually be capitalized when referring to the prescription drug. While this nomenclature has not caught on because the name 'methylone' became widely used before the conflicting Methylone trademark was noticed, the analogous names for related chemicals bk-MDEA and bk-MBDB have become the established names for those substances. From Wikipedia, the free encyclopedia. This article may be too technical for most readers to understand. Please help improve it to make it understandable to non-experts , without removing the technical details. March Learn how and when to remove this template message. For other uses, see MDMC disambiguation. Not to be confused with ethylone. Retrieved 17 June European Journal of Pharmacology. Archived from the original on Methcathinone and 2 methylamino 3,4-methylenedioxyphenyl propanone methylone selectively inhibit plasma membrane catecholamine reuptake transporters. Metabolism of methylone in humans and rats. Archived from the original on 9 February Retrieved 23 October Retrieved 3 April Archived PDF from the original on Archived from the original on 10 November Retrieved 28 March Archived from the original on 18 October USA Dept of Justice. Archived from the original on 25 April Retrieved 22 April Placement of Methylone Into Schedule I'. Archived from the original on 17 April Archived PDF from the original on 1 September Archived from the original on 15 December Adapromine Amantadine Bromantane Memantine Rimantadine. Oxiracetam Phenylpiracetam Phenylpiracetam hydrazide. SoRI Adrenergic release blockers: Retrieved from ' https: All articles with dead external links Articles with dead external links from January Articles with permanently dead external links Webarchive template wayback links Wikipedia articles that are too technical from March All articles that are too technical Articles needing expert attention from March All articles needing expert attention Drugs with non-standard legal status Articles with changed CASNo identifier Articles without EBI source Chemical pages without DrugBank identifier Articles without KEGG source Drugboxes which contain changes to verified fields Drugboxes which contain changes to watched fields All articles with unsourced statements Articles with unsourced statements from July Articles with unsourced statements from April All articles lacking reliable references Articles lacking reliable references from May Views Read Edit View history. In other projects Wikimedia Commons. This page was last edited on 7 July , at By using this site, you agree to the Terms of Use and Privacy Policy. IV or IM injection , rectal.

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